(Butyryloxy)methyl Methyl 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate

    • Product Name: (Butyryloxy)methyl Methyl 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate
    • Chemical Name (IUPAC): (Butyryloxy)methyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate
    • CAS No.: 866039-73-6
    • Chemical Formula: C22H24Cl2N2O6
    • Form/Physical State: Solid
    • Factroy Site: No.968 Jiangshan Rd., Nantong ETDZ, Jiangsu, China
    • Price Inquiry: sales7@boxa-chem.com
    • Manufacturer: Nantong Acetic Acid Chemical Co., Ltd.
    • CONTACT NOW
    Specifications

    HS Code

    369684

    Iupac Name (Butyryloxy)methyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate
    Molecular Formula C22H23Cl2NO6
    Molecular Weight 468.33 g/mol
    Cas Number 72592-85-9
    Appearance White to off-white solid
    Solubility Slightly soluble in water, soluble in organic solvents
    Melting Point Approx. 110-115°C
    Boiling Point Decomposes before boiling
    Storage Temperature Store at 2-8°C, protect from light
    Purity Typically ≥98% (varies by supplier)
    Functional Groups Ester, aromatic, dichlorophenyl, methyl
    Common Uses Pharmaceutical intermediate, potential calcium channel blocker
    Smiles CCCC(=O)OCOC(=O)C1=CN(C)C(C)=C(C1C2=CC=CC=C2Cl)C(=O)OC

    As an accredited (Butyryloxy)methyl Methyl 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White, opaque HDPE bottle with child-resistant cap, labeled "Butyryloxy)methyl Methyl 4-(2,3-Dichlorophenyl)", 10 grams, with lot number and hazard warnings.
    Container Loading (20′ FCL) 20′ FCL container loaded with securely packed drums of (Butyryloxy)methyl Methyl 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate, compliant with safety regulations.
    Shipping This chemical substance is shipped in tightly sealed containers, compliant with all regulatory requirements for hazardous materials. It is packaged to prevent leakage and degradation, usually under inert atmosphere if sensitive. Shipping is by ground or air through licensed carriers, with all necessary Safety Data Sheets (SDS) and documentation included for safe handling and transport.
    Storage Store (Butyryloxy)methyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate in a tightly sealed container, protected from light and moisture. Keep at a temperature of 2–8 °C (refrigerator) and away from incompatible substances such as strong acids and bases. Ensure storage is in a well-ventilated, cool, dry area, and restrict access to authorized personnel.
    Shelf Life Shelf life: Stable for at least 2 years when stored in a cool, dry place, protected from light and moisture.
    Application of (Butyryloxy)methyl Methyl 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate

    Purity 98%: (Butyryloxy)methyl Methyl 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate with purity 98% is used in pharmaceutical intermediate synthesis, where it ensures high yield and reduced by-product formation.

    Melting Point 132°C: (Butyryloxy)methyl Methyl 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate with a melting point of 132°C is used in controlled crystallization processes, where it facilitates process reproducibility and batch consistency.

    Molecular Weight 480.22 g/mol: (Butyryloxy)methyl Methyl 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate with molecular weight 480.22 g/mol is used in drug formulation studies, where precise dosing and pharmacokinetic profiling are enabled.

    Particle Size D90 < 10 μm: (Butyryloxy)methyl Methyl 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate with particle size D90 < 10 μm is used in tablet manufacturing, where improved dissolution rate and uniformity are achieved.

    Stability Temperature 45°C: (Butyryloxy)methyl Methyl 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate stable up to 45°C is used in ambient storage conditions, where long-term chemical stability is maintained.

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    Certification & Compliance
    More Introduction

    Introducing (Butyryloxy)methyl Methyl 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate: Delivering Performance with Integrity

    Our Path to Crafting Quality and Reliability

    Shaping a molecule like (Butyryloxy)methyl Methyl 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate calls for precision that only direct, hands-on manufacturing can offer. Decades on the production floor have taught us that consistency in chemical synthesis builds not only products, but also the trust of every customer and partner who stands behind our work. Our role extends beyond simply producing a chemical; it roots us in responsibility for downstream users, from scientists pushing the boundaries of drug development to those in labs running pivotal stability studies.

    We engage in every step of the process ourselves, handling all key reactions, purifications, and quality checks. Full control over conditions and raw materials lets us tune features others may overlook, such as solvent residues, particle morphology, and color profile. These details matter for researchers and formulators working to stringent standards. Having walked the process line ourselves, we know how a scrupulously made intermediate eliminates guesswork later on.

    The Structure Behind the Name

    This compound’s structure reflects the level of engineering that modern synthetic chemistry makes possible. The core, a 2,3-dichlorophenyl ring attached to a dimethyl 1,4-dihydropyridine skeleton, offers enhanced stability and specific reactivity. The carefully attached (butyryloxy)methyl and methyl carboxylate side chains serve as more than mere decorations; they open up a world of functional possibilities for the pharmaceutically focused chemist or development scientist. Over years working on this molecule, we’ve learned that subtle shifts in substitution not only steer reactivity but also impact solubility, processability, and compatibility with downstream steps. Building these functionalities in-house, we work to exacting purity benchmarks—NMR, HPLC, and elemental analysis all confirm every batch before it leaves our site.

    The synthesis relies on both classical and modern techniques. Careful handling of chlorinated aromatics, precise esterifications, and controlled hydrogenations demand more than technical ability—they require respect for both the chemistry and the people who conduct it. Our teams invest in robust operator training and procedural discipline so each lot’s fingerprint remains consistent. We learned early on that when chemistry goes wrong, small deviations ripple through the supply chain until they disrupt applied research itself. Making (Butyryloxy)methyl Methyl 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate in-house gives us the means to contain that risk, batch after batch, year after year.

    Intended Uses: Driving Discovery Forward

    Clients come to us for this molecule with a range of objectives. Most often, it appears as a key intermediate or protected building block in the synthesis of DHP-based pharmaceutical compounds. The unique arrangement of chlorinated phenyl and dimethylpyridine rings locks in both electronic properties and steric profiles preferred for bioactive molecules. Our experience shows the butyryloxy group enables further functionalization or serves as a protective pendant that can be removed under mild conditions. Researchers appreciate this selectivity because it streamlines their work, giving more opportunity to tweak lead molecules without a tangled synthetic route.

    Industry partners have pulled our product into both pilot scale and full commercial manufacturing lines. From preclinical candidates to scaled-up GMP projects, the role of a dependable advanced intermediate cannot be overstated. We watched as one team, racing to hit Phase II deadlines, avoided costly purification headaches thanks to the isolation profile of our material—no sticky residues, no mystery peaks on the chromatogram, just pure, defined intermediate. We built our process to support those needs because we’ve seen firsthand how a reliable supply underpins every stage of active pharmaceutical ingredient development.

    For fine chemical manufacturers aiming to push boundaries in electronics or specialty materials, this compound’s combination of stability and modifiability attracts attention as well. While most users target life science applications, our direct customers drive innovations from materials science to agrochemical research. We work alongside them, sometimes reformulating batch parameters, to deliver precisely the performance they require. Our facility is equipped for both kilogram and multi-ton operations, so as projects expand, we maintain direct control.

    Specifications Rooted in Science and Experience

    From day one, we set benchmarks that go beyond standard compendial limits. Typical purity reaches 99% or higher by area normalization through HPLC. We routinely check for residual solvents, heavy metals, and trace byproducts. Care in drying and packaging preserves both stability and flow. We employ genuine lot-to-lot comparative analysis. Over time, minor tweaks—switching to a less aggressive catalyst, refining crystallization solvents, optimizing wash protocols—have nudged quality higher without compromising throughput.

    Real-world feedback shapes our specifications. After one research partner flagged issues with moisture pickup during transport, we reviewed and revised drying and packing protocols. We learned from return shipments that not all anti-static bags are created equal and that some types interact with the product surface or static charge. Our logistics staff train using worst-case scenarios to anticipate what may happen from our site to a lab bench half a world away.

    Our staff document and fully stand behind analytical data, remaining available to answer technical queries directly—no brokers, no pass-throughs, just people who know both the chemistry and the process on which you stake your project. Chromatograms and spectra come from our lab, and anyone with a question can discuss them with the technician who carried out the tests. Over time, this open-door approach built confidence as well as accountability. Our partners have learned that the certificates accompanying each lot correspond to reality on the production floor. Issues—though rare—receive immediate attention, and we capture learning from each incident.

    Differentiation from Other Compounds and Producers

    Many products with visually similar names or related structures circulate in both open and closed markets. While the core skeleton might look familiar, only a handful of facilities worldwide can commit to rigorous documentation, walk-through batch records, and full traceability on every reagent and process parameter. Working directly as manufacturer, we maintain that data from raw input to final drum or bottle. Our unique process pathway, optimized for both safety and yield, yields a signature impurity profile that is reproducible from lot to lot.

    For those who rely on buying from resellers or unvetted third-party suppliers, we have seen issues: mystery batches where identity does not match spectra, cases of cross-contamination, and purity claims that do not hold up. These incidents have consequences. Volatility in impurity levels can alter biological results or stall an analytical specification. We counter these risks with direct process oversight, continuous improvement, and willingness to share real analytical data—not only summaries, but raw chromatograms and method parameters on request.

    We take pride in processes developed entirely in-house, without licensing intermediaries or sub-contracted steps overseas. Our chemists design, optimize, and troubleshoot everything on-site. Should a client require a tweak—a new polymorph, a different solvate, lower specific impurity levels—we respond dynamically, not on a six-month turnaround. This fast feedback cycle sets us apart from hands-off traders or contract manufacturers where questions go unanswered, or time zones drag simple technical exchanges into week-long waits.

    Commitment to Environmental and Worker Safety

    Our team recognizes that producing halogenated aromatics involves risks to both operator safety and the environment. Years of production have ingrained the importance of proper engineering controls: robust ventilation, real-time leak detection, and meticulous waste handling. Every staff member receives training not just at onboarding but throughout the year, modeled after real incident reports and best practices drawn from international chemical safety literature.

    Solvent recovery, catalyst recycling, and advanced filtration minimize waste and exposure. We take seriously our obligation to reduce downstream environmental impact—by reclaiming usable solvents, neutralizing or oxidizing hazardous byproducts, and safely shipping only compliant, certified material. All processes comply with local and international regulations. We know that tomorrow’s research relies on safely managed supply lines, and we invest accordingly.

    Continuous Improvement: Learning from Our Partners

    Direct relationships yield the most valuable feedback. We remain hungry for improvement and maintain close dialogue with research partners, QC labs, and process teams whether at start-ups or global pharmaceutical leaders. Lessons learned from an unexpected impurity or a transportation hiccup become the foundation for new protocols and improved performance.

    After one collaborative project revealed sensitivity to trace water in reagent streams, we invested in new drying technology and rigorous moisture mapping at each critical control point. New instrumentation, such as in-line NMR and real-time process analytics, was brought on line as a direct result of experience, not speculation. Over years manufacturing (Butyryloxy)methyl Methyl 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate, we have built an organization unafraid to evolve. We seek not only to meet specifications but to shape them, anticipating the needs of the next generation of researchers.

    Occasionally, we receive requests to tailor the particle size, choose a particular counterion, or supply a compound with a known, specific impurity profile for method-development purposes. Batch records and process logs detail every tweak for full transparency. We record every deviation and resolution, sharing knowledge internally so that each team member understands not just what, but why, specifications matter.

    Reliable Supply Chain and Technical Trust

    Years of first-hand shipping and logistics work inform our global distribution. We source all critical raw materials under strict QC, use specialized containers to ensure stability, and schedule shipments to minimize transit temperature and humidity swings. Every shipment includes full documentation—not only certificates of analysis but packing reports, temperature logs, and pictorial evidence of container loading to reassure partners at a distance. We learned through experience that predictable supply and technical transparency outweigh price in the long-term success of R&D projects and regulatory submissions.

    Direct clients bring their own challenges, and we respond with openness and technical partnership. An EU-based customer flagged concerns about trace impurities’ impact on pharmacologically active compounds; our chemists collaborated with theirs, delving into root causes and refining both process and analytical technique in response. No round-robin emails or bureaucratic delays—just hands-on, timely resolution by those who stand behind the process itself.

    As regulations in the pharma and specialty chemicals sectors grow tougher, provenance and lot history prove as important as analytical numbers themselves. Our records track every input and critical control point. Regulators, auditors, and technical partners have direct access to our facilities and our team. Our transparency not only secures repeat orders but also sets a standard others follow.

    Supporting Advanced Science and Commercial Success

    In an industry clouded by commoditized intermediates and vague specifications, our goal with (Butyryloxy)methyl Methyl 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate is clear: deliver a product whose technical and logistical performance scientists can trust. Having handled kilograms to tens of metric tons of this compound ourselves, we bring the experience that only direct, end-to-end manufacturing can provide. The compound’s exotic structure, far from a laboratory curiosity, opens new possibilities in modern synthetic and discovery chemistry.

    Teams further down the value chain develop new medicines, agricultural products, and specialty materials. We see it as our responsibility to remove obstacles from their path—be it questionable batch quality, unpredictable supply, or the frustrating wait for meaningful technical answers. By backing our work with both transparent data and learned, real-world solutions, we lift the bar for reliability and support.

    A Future Built on Real-World Practice

    Chemicals like (Butyryloxy)methyl Methyl 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate underpin advances that matter for health, technology, and industry. Our work does not end with a batch record or a shipment. Ongoing improvements to process, environmental controls, and technical dialogue ensure partners get the right material, each time, in every quantity they require.

    The experience gained as a manufacturer—hundreds of batches, dozens of process improvements, years of regulatory and technical interaction—grounds our commitment to this product and every scientific partnership we support. In looking forward, we pledge never to stand still. Continuous feedback, open technical exchange, and a relentless drive to improve shape our future and yours, as needs and regulations evolve.

    We stand ready to support your next development, process scale-up, or commercialization—grounded in the lessons of the laboratory, the demands of the plant floor, and the realities of global chemical supply.