|
HS Code |
142429 |
| Cas Number | 7456-87-3 |
| Molecular Formula | C5H5N3O2 |
| Molecular Weight | 139.11 g/mol |
| Iupac Name | 3-nitropyridin-2-amine |
| Appearance | Yellow to orange crystalline powder |
| Melting Point | 141-146 °C |
| Solubility In Water | Slightly soluble |
| Density | 1.41 g/cm³ |
| Purity | Typically ≥98% |
| Smiles | C1=CC(=NC=C1N)[N+](=O)[O-] |
| Synonyms | 2-Amino-3-nitropyridine |
| Storage Conditions | Store at room temperature, dry and away from light |
As an accredited Amino-3-nitropyridine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | A 25-gram sample of Amino-3-nitropyridine is packaged in a sealed amber glass bottle with a clear, chemical-resistant label. |
| Container Loading (20′ FCL) | A 20′ FCL contains securely packed drums or bags of Amino-3-nitropyridine, ensuring safe and moisture-free chemical transport. |
| Shipping | Amino-3-nitropyridine should be shipped in tightly sealed containers, protected from light, moisture, and incompatible substances. It must comply with relevant hazardous material regulations, typically as a Class 6.1 toxic substance. Proper labeling and documentation are required, and it should be handled by trained personnel using approved shipping methods to ensure safety. |
| Storage | Amino-3-nitropyridine should be stored in a tightly closed container in a cool, dry, and well-ventilated area away from direct sunlight and incompatible substances such as strong oxidizers and acids. It should be kept away from ignition sources and moisture, and stored at room temperature. Proper labeling and access controls should be maintained to ensure safety and prevent accidental exposure. |
| Shelf Life | Amino-3-nitropyridine typically has a shelf life of 2 years when stored in a cool, dry, and airtight container. |
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Purity 99%: Amino-3-nitropyridine Purity 99% is used in active pharmaceutical ingredient synthesis, where high purity ensures optimal reaction yield and consistency. Melting Point 148°C: Amino-3-nitropyridine Melting Point 148°C is used in heterocyclic compound production, where stable melting behavior facilitates controlled processing. Molecular Weight 139.12 g/mol: Amino-3-nitropyridine Molecular Weight 139.12 g/mol is used in agrochemical intermediate manufacturing, where precise molecular mass aids formulation accuracy. Particle Size < 100 µm: Amino-3-nitropyridine Particle Size < 100 µm is used in dye synthesis, where fine particle distribution improves solubility and reaction kinetics. Stability Temperature up to 80°C: Amino-3-nitropyridine Stability Temperature up to 80°C is used in catalyst development, where thermal stability maintains performance under operational conditions. Assay ≥98%: Amino-3-nitropyridine Assay ≥98% is used in specialty polymer production, where high assay values contribute to reproducible polymer quality. Moisture Content < 0.5%: Amino-3-nitropyridine Moisture Content < 0.5% is used in electronic materials preparation, where low moisture minimizes risk of unwanted side reactions. |
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Amino-3-nitropyridine stands as a unique option among pyridine derivatives, appreciated for its chemical structure and the ways it opens doors in synthesis and development. Its molecular formula, C5H5N3O2, marks a simple frame, yet it provides a platform that welcomes modification and innovation. Compared with more common nitrogen-containing building blocks, this compound carves out a clear niche. Chemists aiming to develop specialty dyes, advance pharmaceutical research, or get a foothold in agrochemical projects may find themselves looking here for an edge.
In my experience working with specialty intermediates, too many products float around without a clear role or end use. Amino-3-nitropyridine speaks the language of utility. In the lab, its nitro group sits on the third position of the ring – a subtle placement that changes the game for reactivity. The molecule behaves with a balance of stability and reactivity, supporting a range of transformations. Often that difference – a simple tweak in the ring or a functional group swap – sets the tone for an entire series of experiments or industrial processes. Here, small differences offer real value.
Amino-3-nitropyridine doesn’t shout with a fancy brand name or trademark, but its chemical fingerprint is distinct. It forms a solid at room temperature, usually found as a yellow to orange crystalline powder. This color hints at the light-absorbing nitro group, which draws interest in dye synthesis or optical materials. Solubility lines up with other small pyridine derivatives; it faces water with some reluctance, yet responds to the right organic solvents. This practical trait can save hours – I’ve seen other intermediates gum up glassware, wasting time and patience on cleanup.
Specifications for a laboratory or industrial batch focus on purity, appearance, and residual moisture. In my own projects, a consistent product color and low water content make a huge difference, especially with compounds that like to take up moisture. Supplies of high-purity Amino-3-nitropyridine help the synthesis flow, sparing researchers the downstream hassle of cleaning up unexpected byproducts. That reliability creates a smoother day-to-day workflow for seasoned researchers and new hands alike.
Talking with researchers who chase new targets in pharmaceutical chemistry, I hear Amino-3-nitropyridine mentioned for routes to heterocyclic drugs. Its dual functional groups – an amino on one end, a nitro on the other – let it serve as a robust bridge in multi-step syntheses. This pairing naturally invites substitution, reduction, or cyclization, creating backbones for candidate molecules that fill real gaps in treatment strategies. For scientists, that means a chance to try something novel, without having to reinvent the wheel with each new synthesis.
Beyond pharma, dye chemists value the molecule, tapping its unique reactivity for custom pigments in sectors from textiles to high-definition printing. The balance of the ring system with reactive sites means a chemist can dial in the right features at the right step. Even so, production isn't stuck in the past; some modern uses dig into electronic materials, where compounds like this can help bring fine-tuned properties to organic semiconductors or sensing devices.
On the manufacturing floor, the simple handling makes Amino-3-nitropyridine preferable to thorny or hazardous alternatives. The solid’s low volatility, moderate toxicity, and predictable storage needs mean fewer headaches compared to certain raw materials in the same category. I remember colleagues who had to update entire sets of safety protocols just to bring in harder-to-handle nitro aromatics; this product usually lets teams stick with standard best practices.
Stacked against more familiar pyridines, Amino-3-nitropyridine answers a specific call in the synthetic pathway. Take 4-nitropyridine or other amino-substituted pyridines; they come with different reactive profiles, and those changes reflect in end products. While some rivals boast easier reductions or sharper color profiles, this compound’s unique pattern – especially the meta relationship on the ring – marks it out for particular coupling reactions or reductions. That allows for more direct or more atom-efficient routes to complex targets.
I’ve worked with nitroaromatic intermediates that required elaborate process tweaks just to avoid runaway reactions or off-target byproducts. In contrast, Amino-3-nitropyridine’s balanced reactivity has earned it a steady following among process chemists. Many switch to it after fighting messier reactions elsewhere. Fewer side reactions translate to higher yields and a less daunting waste stream.
Compared with halogenated analogs or more toxic nitrogen sources, this aminopyridine cuts both the regulatory and practical load. It offers enough performance margin that companies can slim down risk management protocols, and that means less paperwork and more productivity in the real world.
Of course, products like Amino-3-nitropyridine do not operate in a vacuum. A question on many minds lately boils down to sourcing and sustainability. Small-molecule intermediates face the same logistical hurdles and geo-political disruptions as other chemicals. Working in industry, I've seen moments where routine procurement contracts turn into negotiations over price, purity, and shipment guarantees. The most sought-after chemicals are only as good as their reliable delivery.
Environmental questions also surface now more than ever. Regulatory agencies push for cleaner, safer alternatives across both lab and plant scales. Amino-3-nitropyridine, by virtue of its moderate toxicity and minimized handling risks, moves in this direction — but neither suppliers nor end-users can stop there. Waste minimization, closed-loop systems, and recovery strategies now shape purchasing decisions far more than they did a decade ago. Some production routes generate significant nitroaromatic waste, so teams developing better syntheses stay in demand.
From my own work, I know green chemistry isn't a buzzword for most labs anymore. It’s a real driver for grant funding, process approvals, and even investor support. Integrating recyclability or using bio-based starting materials, wherever possible, stands as the next frontier for classic intermediates like this one. Companies quick to adapt often tip the market their way, while others risk falling behind.
With some chemicals, legacy methods seem carved in stone. Yet Amino-3-nitropyridine has served as a springboard for fresh thinking. The combination of the amino and nitro groups encourages creative synthesis. I’ve seen researchers use the compound as a scaffold for complex combinatorial libraries, flipping the usual approach by letting the molecule’s polarity guide selection. In these settings, a single intermediate can power the search for lead compounds in months, where custom synthesis would take years.
Even as advanced automation and AI shape pharmaceutical discovery, the core building blocks stay relevant. Amino-3-nitropyridine fits these modern workflows. Its straightforward isolation, predictable liquid chromatography properties, and stability under standard conditions mean it plugs directly into automated high-throughput screening or flow chemistry setups.
Turning to material science, demand for organic electronics and light-absorbing films opens doors for this classic molecule. Its substitution pattern can help tune energy levels in organic field-effect transistors or charge-transport materials. Speaking with polymer chemists, I hear consistent calls for pyridine derivatives that handle elevated temperatures without decomposing or crosslinking in unpredictable ways. Here, incremental improvements can turn into big wins for downstream applications.
Drawing from what I see across supply departments, a trusted source for Amino-3-nitropyridine is not just about the lowest price. It involves supplier transparency, logistics, and real-time documentation. Teams expect certificates of analysis, robust safety data, and rapid shipping to keep projects moving. Last year, a delay on a shipment set back an entire production campaign; months of bench work got stuck due to a single missing intermediate.
A resilient supply chain now matters as much as the compound’s chemical merits. Researchers and purchasing teams ask tougher questions about cross-border shipment and compliance with global chemical control regulations. Those considerations drive many companies to diversify their suppliers and invest in better relationships with producers who understand both the end-use requirements and the regulations that come with them.
Quality control doesn't stop at the supplier’s dock. Labs now use in-house verification—NMR, HPLC, melting point checks—to confirm batch-to-batch consistency. I've seen enough ruined reactions from sloppy production standards to know that every verification step pays off in the long run.
Bringing any nitroaromatic compound onto the bench or the plant floor involves a careful look at health and safety. Amino-3-nitropyridine rates as less volatile than some of its cousins, but prudent handling remains critical. Working in both academic and plant settings, I value those days when routine procedures mean less anxiety for both trainees and long-term staff. Consistent education on dust control, skin protection, and spill response makes a difference beyond regulatory compliance—it builds trust and a better workplace.
Safety documentation and clear labeling go hand in hand with these practices. In labs with a rotating cast of new researchers, having protocols posted and reinforced during onboarding is now non-negotiable. The more user-friendly the chemical, the smoother the operation—but it's never “set and forget.” Each batch and each process review looks for better engineering controls and lower exposure risks. Investing in good workflow pays off, especially in industries focused on worker well-being and product stewardship.
Amino-3-nitropyridine does not enjoy brand-name recognition outside technical circles, but its impact filters down into everyday products. Pharmaceutical pipelines depend on intermediates with the versatility to fuel discovery—even small changes can touch lives through new therapies. Dye technologies using custom-built molecules help industries keep pace with trends in fashion, security printing, or sensor technology.
Technological progress often reads like a story of great leaps, yet in the chemical industry, incremental improvements and reliable supplies often drive the big wins. The steady role of intermediates like Amino-3-nitropyridine might lack glamour, but the scientists shaping new materials and medicines notice and reward the practical workhorses.
From my vantage point, progress and safety track closely together. Each advance brings a responsibility to rethink environmental impact, manufacturing safety, and waste minimization. Research leaders who step up to strengthen transparency around sourcing and safety will help set higher standards across the field.
For buyers and users of Amino-3-nitropyridine, established trust and nimble logistics build confidence. Investing in long-term supply agreements with proven producers helps insulate against market shocks and supply bottlenecks. Review of each batch, not just for purity but for consistency in process handling, creates a virtuous cycle—feedback from real users continues to shape supplier processes.
Continued work on greener syntheses deserves strong support. Research groups and industry partners can push for routes that cut down on energy use, hazardous reagents, and side-stream waste. In my own network, the conversations have shifted from “can it be made?” to “how do we make it better—safer, cleaner, faster?” Collaboration across companies and academic labs accelerates progress, both for established products and new generations of specialty intermediates.
Education and outreach also matter. As workforce demographics shift and younger chemists take the helm, systematic training in proper handling, storage, and environmental management ensures the next wave of researchers can use these key compounds without undue risk. The most forward-thinking organizations combine routine protocols with open dialogue, turning safety and stewardship into living, evolving practices.
In the end, Amino-3-nitropyridine stands as a testament to the power of robust, thoughtfully designed intermediates in the chemical world. For teams who demand reliability, flexibility, and solid performance, it meets the real-world challenges that come up daily in labs and production environments. The fine balance of reactivity and manageability makes it worth continued attention, both as a building block for the current generation and as a model for how the industry can move forward responsibly. In the hustle of everyday synthesis or manufacturing, its steady performance keeps vital projects on track.