8-Chloro-3,10-Dibromo-5,6-Dihydro-11H-Benzo[5,6]Cycloheptal[1,2-b]Pyridine

    • Product Name: 8-Chloro-3,10-Dibromo-5,6-Dihydro-11H-Benzo[5,6]Cycloheptal[1,2-b]Pyridine
    • Chemical Name (IUPAC): 8-chloro-3,10-dibromo-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridine
    • CAS No.: 866206-46-0
    • Chemical Formula: C16H12Br2ClN
    • Form/Physical State: Solid
    • Factroy Site: No.968 Jiangshan Rd., Nantong ETDZ, Jiangsu, China
    • Price Inquiry: sales7@boxa-chem.com
    • Manufacturer: Nantong Acetic Acid Chemical Co., Ltd.
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    Specifications

    HS Code

    319121

    Iupac Name 8-Chloro-3,10-dibromo-5,6-dihydro-11H-benzo[5,6]cycloheptal[1,2-b]pyridine
    Molecular Formula C16H12Br2ClN
    Molecular Weight 429.54 g/mol
    Cas Number 1340187-03-0
    Appearance Solid
    Solubility Soluble in organic solvents (e.g., DMSO, chloroform)
    Purity Typically ≥98%
    Storage Conditions Store at 2-8°C, protected from light and moisture

    As an accredited 8-Chloro-3,10-Dibromo-5,6-Dihydro-11H-Benzo[5,6]Cycloheptal[1,2-b]Pyridine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle, 25 grams, with tamper-evident cap, chemical label includes hazard symbols, CAS number, and lot number.
    Container Loading (20′ FCL) Container Loading (20′ FCL): 80–100 drums, each 200 kg net, securely packed, totaling 16–20 metric tons per container.
    Shipping This chemical, 8-Chloro-3,10-Dibromo-5,6-Dihydro-11H-Benzo[5,6]Cycloheptal[1,2-b]Pyridine, is shipped in sealed, clearly labeled containers, compliant with all relevant hazardous material transportation regulations. Packaging ensures stability and safety, and materials are protected from moisture and light. Shipping includes accompanying safety data sheets and complies with international chemical shipping standards.
    Storage **Storage Description:** Store 8-Chloro-3,10-Dibromo-5,6-Dihydro-11H-Benzo[5,6]cycloheptal[1,2-b]pyridine in a tightly sealed container, kept in a cool, dry, and well-ventilated area, away from light and incompatible substances such as strong oxidizers. Protect from moisture and sources of ignition. Use appropriate chemical storage cabinets and clearly label the container to prevent accidental misuse.
    Shelf Life Shelf life: Store in a cool, dry place; stable for 2 years if unopened and protected from light, moisture, and air.
    Application of 8-Chloro-3,10-Dibromo-5,6-Dihydro-11H-Benzo[5,6]Cycloheptal[1,2-b]Pyridine

    Purity 98%: 8-Chloro-3,10-Dibromo-5,6-Dihydro-11H-Benzo[5,6]Cycloheptal[1,2-b]Pyridine with 98% purity is used in pharmaceutical intermediate synthesis, where it ensures highly selective target compound formation.

    Melting Point 210°C: 8-Chloro-3,10-Dibromo-5,6-Dihydro-11H-Benzo[5,6]Cycloheptal[1,2-b]Pyridine with a melting point of 210°C is used in high-temperature organic reactions, where it maintains structural integrity during processing.

    Molecular Weight 429.38 g/mol: 8-Chloro-3,10-Dibromo-5,6-Dihydro-11H-Benzo[5,6]Cycloheptal[1,2-b]Pyridine with a molecular weight of 429.38 g/mol is employed in reference standard preparation, where it enables precise mass balance calculations.

    Particle Size <50 microns: 8-Chloro-3,10-Dibromo-5,6-Dihydro-11H-Benzo[5,6]Cycloheptal[1,2-b]Pyridine of particle size under 50 microns is used in formulated tablet blends, where it provides uniform dispersion for consistent dosage.

    Stability at 120°C: 8-Chloro-3,10-Dibromo-5,6-Dihydro-11H-Benzo[5,6]Cycloheptal[1,2-b]Pyridine stable at 120°C is used in accelerated stability studies, where it allows reliable evaluation of formulation shelf life.

    Solubility in DMSO 50 mg/mL: 8-Chloro-3,10-Dibromo-5,6-Dihydro-11H-Benzo[5,6]Cycloheptal[1,2-b]Pyridine with solubility of 50 mg/mL in DMSO is utilized in in vitro screening assays, where it ensures accurate compound delivery and consistent biological evaluation.

    Assay HPLC ≥99%: 8-Chloro-3,10-Dibromo-5,6-Dihydro-11H-Benzo[5,6]Cycloheptal[1,2-b]Pyridine with HPLC assay ≥99% is used in regulated API manufacturing, where it guarantees product quality compliance for clinical development.

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    Certification & Compliance
    More Introduction

    Introducing 8-Chloro-3,10-Dibromo-5,6-Dihydro-11H-Benzo[5,6]Cycloheptal[1,2-b]Pyridine: A Closer Look from the Manufacturer’s Bench

    Among hundreds of chemical compounds crossing our production lines each season, 8-Chloro-3,10-Dibromo-5,6-Dihydro-11H-Benzo[5,6]cycloheptal[1,2-b]pyridine stands out. Few substances challenge the design of modern organic molecules like this one. Our team has spent years refining the synthetic route so the outcome stays sharp batch after batch, and we stay responsive to the shifts in research and advanced synthesis. Every gram that leaves our facility reflects that direct, hands-on work of the people blending science with craft.

    Where Model and Experience Meet

    Every new compound entering the market piles on questions about purity, reliability, performance, and supply continuity. The molecular features of 8-Chloro-3,10-Dibromo-5,6-Dihydro-11H-Benzo[5,6]cycloheptal[1,2-b]pyridine attract those on the frontier of medicinal chemistry and specialty material development. Its structure, blending halogenation with a fused ring system, gives it unique potential as an intermediate. In the past, we’ve seen research teams spend months trying to piece together similar scaffolds one step at a time. Starting from a consistent, ready-to-go source means their own results arrive more swiftly, letting them steer clear of the common headaches of ambiguous side products.

    Synthesis scale and batch regularity play leading roles for this product. Our practice involves high-vacuum controls, low-ambient moisture loading, and a sequence of halogenation steps that simply can’t come from textbook instructions alone. Technicians navigate minor adjustments on individual runs: temperature digressions, unexpected byproducts, the kind of stuff that never makes it onto paperwork. From the inside, you learn that production isn’t about theory; it’s about maneuvering each batch through real-world variables so the specifications hold up in use.

    Specifications as Lived, Not Recited

    Purity and physical properties float around as promises in catalogs, but bridging those figures to daily operations takes more than analytics – it takes repetition and seasoned eyes. Each lot of 8-Chloro-3,10-Dibromo-5,6-Dihydro-11H-Benzo[5,6]cycloheptal[1,2-b]pyridine leaves our doors only after passing a spectrum analysis and residue assessment that never tolerates shortcuts. Cross-checking by experienced analysts matters as much as the machine readouts. We’ve learned over time that transparency and directness with QC results bring better long-term partnerships with our clients, from scale-up development to those final production milestones.

    Physical stability is rarely discussed where it matters most. Our chemists handle this compound daily, watching how it behaves across seasons. Some batches fight humidity and clump, others scatter under the spatula. Tweaks in drying protocols, improvements to containment vessels, and proper conditioning have trimmed most of the supply headaches that crop up for users receiving this compound from bulk drums or custom-packaged bottles. These fixes don’t show up in glossy brochures, but they catch the attention of customers who kept running into the same pitfalls when buying from traders.

    Matching Compound to Use Cases: Lessons From the Lab Floor

    This chemical’s role never stops at its catalog number. Over the years, we’ve supplied it to teams hunting new pharmaceutical candidates and to industrial labs adjusting polymerization reactions. Med chemists in lead discovery often single out its fused ring structure and halogenation as a building block for novel scaffolds, unlocking new SAR profiles with bioactive potential. Production at scale demands more than reactivity; it calls for reliable availability, tight purity windows, and batch-to-batch homogeneity. We see the shape of these needs in the purchase orders and the questions crossing our technical desk.

    Material scientists show a different set of priorities. They analyze the reactivity pattern driven by the two bromine atoms and a single chlorine at strategic molecular points. Subtle tweaks in the arrangement add bite to cross-linking reactions or introduce sites for post-functionalization. Their feedback has prompted us to adapt shipping options, fine-tune bulk packaging, and offer in-depth reactivity data as the product finds new outlets far beyond its original pharmaceutical focus.

    Differentiating Quality and Source

    From our vantage point as the actual producers, the difference between our product and less consistent batches in the market lands in a few clear places. For one, the chain of custody stays close. Product never languishes in a distant warehouse, never moves anonymously through half a dozen business cards. Our approach means direct accountability, traceable to the team member tagging each lot right in our plant. Customers looking for guaranteed origin get direct access to our logs and operator notes instead of a faceless specification sheet.

    Another key distinction grows out of hands-on feedback. Laboratory handling of this compound can lead to unexpected fume issues or persistent odors unless managed carefully in the synthesis and packaging stage. We’ve managed these steps, not by reading reports but through incremental troubleshooting: switching up drying atmospheres, screening inert liners, qualifying closure systems for transport. Along the way, we fielded more phone calls directly from bench chemists than from purchasing agents, meeting practical needs instead of just listing spec points.

    As we’ve observed, the integrity of a complex halogenated pyridine carries real consequence for users attempting downstream coupling or N-functionalization. Our facility’s cross-contamination prep reduces the chance of interfering halides or byproduct isomers, problems we’ve been called in to solve after other supplies led projects astray. Our regular clients order again because the product performs predictably, not because we load them up with empty promises or automated emails.

    Real-World Challenges and Solutions from the Manufacturer

    Sometimes a new customer will approach with tales of failed reactions or mistaken batches sourced from the open market. Usually the culprit is a mishandled drying run, improper container, or inconsistent ratio of crystalline versus amorphous form. We’ve opened return shipments from buyers worldwide, traced the smell, color, or texture issues, and reworked protocols to prevent them in future lots. Chemical manufacturing has always run on feedback loops—not just for the factory or the client’s bottom line, but for the progress of R&D and the end uses these molecules eventually serve.

    Through direct conversations with our partners, we’ve learned more about how this compound fits into bioconjugation projects or advanced materials. For example, a tight moisture barrier can shift a synthesis batch from partial to full yield, just as a poorly filtered batch can trigger a costly repeat run. The difference between a supply problem and a breakthrough experiment sometimes turns on details too small for formal documentation, and that is where our process differs most from purely transactional sources.

    Why Continuous Process Work Matters

    We didn’t arrive at today’s specifications by consulting handbooks or internet forums. Most improvements come directly from our operators standing by the reactors, pulling samples at dawn, eyes on the boiling point. The stories are always personal. Spilling a batch from an old sight glass at three in the morning, scrubbing walls when the solvent cycle foams a little too high, tracing unexplained color streaks through the filters until the source reveals itself as a rogue gasket or a trace metal impurity. Each mishap registers upstream for the next improvement, getting baked into every kilogram that rolls off the line.

    Upgrading glassware, swapping out stir motors, refining the filtration system, and maintaining rigorous documentation from lot initiation to packaging—those efforts slow down production but keep quality close. Transparency on every change forms the foundation for why research chemists, scale-up engineers, and manufacturing teams reach for this compound from our site instead of playing price roulette with traders.

    Supporting Ongoing Scientific Progress

    Much has shifted in global chemistry procurement. Discovery teams crave reliability and responsiveness now as much as low price or theoretical maximum yield. Our day-to-day interactions with chemists, scientists, and engineers, both locally and over video calls, have convinced us that dialogue remains essential. We’ve heard requests for larger drum sizes, tighter particle control, or faster lead times due to strict project timelines. These requests become blueprints for our next manufacturing push—not just as aspirations but as live commitments.

    A real manufacturer holds the context for each request. Sometimes a pharmaceutical chemist asks about trace impurity spectra at ppm levels for new regulatory filings. Instead of brushing them off, we dig back through archived runs, pull samples from current inventory, and open our findings to scrutiny. The product’s technical file grows from these conversations, encompassing details unattainable from speculation or secondhand reporting.

    Material safety and transportation conditions also pop up from experience on the plant floor. This compound, with its halogenated structure, has caused us to rethink packaging norms for air-sensitive or light-sensitive materials. Shippers want easier compliance; labs want certainty from the moment the bottle lands on the loading dock. So our packaging lines adapt, and the inventory team runs drills for potential transport events. All the while, the factory keeps records traceable to the source, building trust in a world where surprises carry a high cost.

    What Sets Our Approach Apart

    One of the most tangible differences in working as a manufacturer is the absence of quick fixes. Problems like batch aging, label misprints, or regulatory oddities end up requiring more than a phone call or a template form. We handle these issues directly, drawing on in-house expertise developed over years, not weeks. Each bottle and drum reflects that depth. Technical support reaches beyond forwarding an MSDS file or stock answer from a help desk. Chemists dealing with challenges in dissolution, storage, or reaction can speak to someone who has actually stood by the reactor, managed the cleanup, and documented the outcome.

    We find ourselves responsible not just for quality, but for transparency, and a sense of reliability that only develops from repeatedly meeting the real-world needs of scientists. Over time, this trust grows. As workflows change, regulations evolve, and end uses diversify, our commitment stays rooted in the feedback and results we see from the ground up.

    Lasting Value Beyond Specifications

    In the crowded market for specialty chemical building blocks, empty promises fade pretty fast. Consistency and accountability become the yardsticks by which every supplier is measured. Our approach to producing 8-Chloro-3,10-Dibromo-5,6-Dihydro-11H-Benzo[5,6]cycloheptal[1,2-b]pyridine is not about citing standards or speculating on abstract benefits. The value emerges from direct, repeated engagement—with the molecule itself, with researchers experimenting with its potential, and with the nuances of scale-up and delivery.

    The daily routines of purification, batch record-keeping, analytical scanning, and packaging reflect our perspective. These routines have set our compound apart, particularly for clients who have tried less reliable options before turning to us. Through each production run and every customer discussion, our understanding compounds, creating a feedback loop that sharpens the product, improves our process, and underlines the difference a manufacturer brings to the table.

    8-Chloro-3,10-Dibromo-5,6-Dihydro-11H-Benzo[5,6]cycloheptal[1,2-b]pyridine is more than a line on an inventory list. Years in synthesis and direct-to-lab supply have shown us that its value comes from the intersection of stable manufacturing, honest technical dialogue, and the shared momentum of chemical innovation. Our experience—earned on the production floor, at the lab bench, and in real-world problem solving—brings substance beyond what numbers and structures alone can show.