6-oxo-1,6-dihydropyridine-3-carboxylate

    • Product Name: 6-oxo-1,6-dihydropyridine-3-carboxylate
    • Chemical Name (IUPAC): methyl 6-oxo-1,6-dihydropyridine-3-carboxylate
    • CAS No.: 5444-92-4
    • Chemical Formula: C6H5NO3
    • Form/Physical State: Solid
    • Factroy Site: No.968 Jiangshan Rd., Nantong ETDZ, Jiangsu, China
    • Price Inquiry: sales7@boxa-chem.com
    • Manufacturer: Nantong Acetic Acid Chemical Co., Ltd.
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    Specifications

    HS Code

    949233

    Iupac Name 6-oxo-1,6-dihydropyridine-3-carboxylate
    Molecular Formula C6H5NO3
    Molar Mass 139.11 g/mol
    Appearance White to off-white solid
    Melting Point 140-145°C
    Solubility In Water Moderate
    Pka Estimated 4.2 (carboxyl group)
    Boiling Point Decomposes before boiling
    Density Approx. 1.4 g/cm³
    Logp -0.7 (estimated)
    Smiles O=C1NC=CC(C(=O)O)=C1
    Inchi InChI=1S/C6H5NO3/c8-5-2-1-4(3-7-5)6(9)10/h1-3H,(H,9,10,7)
    Refractive Index 1.54 (estimated)
    Storage Conditions Store at room temperature, dry, protected from light

    As an accredited 6-oxo-1,6-dihydropyridine-3-carboxylate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White, screw-capped amber glass bottle labeled “6-oxo-1,6-dihydropyridine-3-carboxylate, 5 grams,” with hazard and storage instructions.
    Container Loading (20′ FCL) 20′ FCL container loaded with securely packed 6-oxo-1,6-dihydropyridine-3-carboxylate, ensuring safe, moisture-free, and stable transport.
    Shipping The chemical 6-oxo-1,6-dihydropyridine-3-carboxylate is shipped in sealed, chemical-resistant containers, clearly labeled with hazard and handling information. The package is handled according to safety regulations for laboratory chemicals, protected from moisture and extreme temperatures, and accompanied by appropriate documentation, including a Safety Data Sheet (SDS) for transport compliance.
    Storage 6-oxo-1,6-dihydropyridine-3-carboxylate should be stored in a tightly sealed container, protected from light and moisture. Keep it in a cool, dry, and well-ventilated area, away from incompatible substances such as strong oxidizers. Store at room temperature unless otherwise specified, and ensure proper labeling. Avoid exposure to heat, ignition sources, or direct sunlight to maintain chemical stability.
    Shelf Life 6-oxo-1,6-dihydropyridine-3-carboxylate should be stored cool, dry, and protected from light; estimated shelf life is typically 2 years.
    Application of 6-oxo-1,6-dihydropyridine-3-carboxylate

    Purity 98%: 6-oxo-1,6-dihydropyridine-3-carboxylate with purity 98% is used in pharmaceutical intermediate synthesis, where it enhances reaction efficiency and product yield.

    Melting Point 180°C: 6-oxo-1,6-dihydropyridine-3-carboxylate with melting point 180°C is used in high-temperature organic reactions, where it improves process stability and reproducibility.

    Molecular Weight 153.13 g/mol: 6-oxo-1,6-dihydropyridine-3-carboxylate with molecular weight 153.13 g/mol is used in medicinal chemistry research, where it enables precise formulation and dosing studies.

    Particle Size <10 µm: 6-oxo-1,6-dihydropyridine-3-carboxylate with particle size less than 10 µm is used in solid formulation development, where it increases dissolution rates and bioavailability.

    Stability Temperature 60°C: 6-oxo-1,6-dihydropyridine-3-carboxylate with stability up to 60°C is used in storage and transport of chemical stocks, where it prevents degradation and preserves compound integrity.

    HPLC Assay ≥99%: 6-oxo-1,6-dihydropyridine-3-carboxylate with HPLC assay ≥99% is used in active pharmaceutical ingredient (API) validation, where it guarantees consistency and regulatory compliance.

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    Certification & Compliance
    More Introduction

    6-oxo-1,6-dihydropyridine-3-carboxylate — A Closer Look from Our Factory Floor

    Perspective on Precision and Consistency in Production

    In the chemical manufacturing world, reliability starts with what takes place on the factory floor. We spend thousands of hours each year monitoring, analyzing, and refining our synthetic pathways, especially with sensitive compounds like 6-oxo-1,6-dihydropyridine-3-carboxylate. This compound doesn’t just represent another item on a product list — every kilogram reflects a combination of technical understanding and hard-earned experience that drives reproducibility in downstream applications. Years of batch-to-batch production, under finely tuned reaction conditions, have shown us that minor deviations in temperature control or reactant quality dramatically shift yield and purity. Customers in pharmaceuticals, agrochemicals, and advanced materials notice the difference immediately, especially when trace byproducts interfere with their formulations or test results.

    Our 6-oxo-1,6-dihydropyridine-3-carboxylate comes directly from our reactors, never outsourced or repackaged from another source, removing the hidden surprises that can frustrate end users. From the earliest stages of design, we focus on moisture levels, temperature profiles, and the careful choice of catalysts, favoring precise kinetics over shortcuts. Integrating inline analytical tools, like real-time HPLC or NMR monitoring, lets us catch off-spec product before it leaves the reactor, so the powder in your drum matches the technical data you see with your own equipment.

    Detailed Model and Specification Insights

    We manufacture the compound in several targeted grades, which come from direct demand in process chemistry and core research. Our primary models differentiate based on purity thresholds and residual solvent levels, as requested by partners who scale up processes for drug, crop protection or specialty polymer synthesis. Because every reaction step influences downstream isolation, paying attention to process solvent removal and drying stages makes a measurable difference in the stability and storage life of the finished material.

    Our most requested grade offers over 99.5% purity, measured by calibrated chromatographic techniques tied to ISO-accredited standards. Customers in analytical labs confirm that trace metals from glassware or reactor surfaces, including iron, copper and zinc, stay consistently below 10 ppm. That level is possible through months of equipment qualification and rinse validation in our own workstations, not through third-party certificates.

    Particle size control can sway results in both solid-phase and solution-phase experiments. Our standard product runs in the low-micron range, with targeted sieving so that dissolution profiles are reproducible, especially in sample prep workflows. Granularity and dry flowability stem from the time taken during vacuum tray drying and careful product handling, not last-minute blending or anti-caking agents.

    Usage Experiences and Process Demands

    Researchers and process chemists tell us they choose 6-oxo-1,6-dihydropyridine-3-carboxylate because of its versatility as a building block. We’ve seen orders spike from medicinal chemistry groups seeking new heterocyclic frameworks. In those environments, side products or inconsistent melting points create headaches during purification, so our emphasis on minimal impurities pays off. In scale-up environments, the focus is on reliable supply and a product that dissolves swiftly without clogging reactors or forming stubborn slurries. Our drying parameters maintain a low residual moisture content, keeping the material free-flowing and compatible with automated dispensers.

    Seeing our customers’ successes drives our own standards. Some use the compound for amide couplings; others for cyclization steps to form more complex pyridine derivatives. Variability in reactivity, which we’ve linked mainly to trace impurities and subtle tautomeric shifts, decreases dramatically once the material leaves our plant, so their time is spent on product discovery, not troubleshooting supply issues.

    How Our 6-oxo-1,6-dihydropyridine-3-carboxylate Stands Apart

    Markets tend to offer similar-sounding products at first glance, but feedback from repeated use brings the truth into focus. Many competing samples arrive with gradients in color, granular size, or off-odors from incomplete drying or cross-contamination. Several clients have sent us competitor samples for side-by-side comparison, where extra peaks and baseline drift on their chromatograms show higher levels of unreacted precursors or persistent solvents. Strong chemical odors signal insufficient purification; variability in color intensity often tracks with oxidized byproducts picked up in exposed or poorly sealed storage. Our internal policy insists on shipment directly from production flats into tamper-evident packaging, where temperature excursions are tracked and CO2 blanketing maintains integrity on the shelf.

    We invest in closed-system transfer for the most reactive intermediates, then follow up with batch-level analytics using UV, MS and trace-level microanalysis so shipping samples show no significant difference from our master QC retains. This approach has drawn in partners who previously faced dropped yields and stalled project timelines due to inconsistent input materials. Patents and publications citing our product document the exact spectra and batch info, not vague supplier codes.

    Real-World Value vs. Commodity Offerings

    Commodity-grade samples make their way through the market, but they introduce risks that don’t become apparent until a process enters scale-up. Moisture traps, glass residue, or uneven pH adjustment in their work-ups introduce small but nagging sources of error, translating into rotting inventory or unusable byproducts. Every time an order leaves our plant, we’ve signed off down the chain — from reactor operator to warehouse checker — so researchers can rely on their own methods rather than adjusting to unknown variables. We keep parallel production logs so issues reported in the field can be traced to a source and corrected, not swept under the rug.

    Because many resellers rely on relabeling outsourced lots, they can’t offer batch-level traceability or informed troubleshooting, which becomes essential during larger campaigns. Our clients often share case reports about stalled campaigns that find new life once raw material variability drops. One pharmaceutical partner reported time savings of over 15% across three preclinical projects after switching to our in-house produced 6-oxo-1,6-dihydropyridine-3-carboxylate, citing a virtual end to re-ordering or mid-synthesis corrections.

    Direct Connections Between Production and Application

    As a manufacturer, every adjustment in our synthesis protocol gets validated in a real application. If recrystallization time increases or particle size shifts, we measure that effect not just in the lab, but with partners running pilot plants or screening hundreds of derivatives. Maintaining stable crystallinity, for example, improves both compounding and filtration. In a pilot batch for a polymer additive, a simple tweak to our drying filter cut off 20% of fine powder residue, which had been showing up as haze in film-forming applications.

    By focusing on customer-reported endpoints — solubility in proprietary solvents, reaction yield in low-temperature couplings, or even shelf stability under tropical warehouse conditions — we optimize the process to fix actual workflow problems. Major differences from third-party sources come to light in blinded trials, where real users describe improvements in clean-up or variance reduction just from their starting material switch.

    Experience-Driven Solutions for Downstream Issues

    In the world of precision chemistry, input quality can save weeks of troubleshooting. Whenever an issue arises, whether a drop in yield or an unusual side product, we don’t deflect it to a distant technical support line. Our QC and process teams map back every deviation to a batch record, shipping log or even drum seal integrity, and trace root causes down to exact shifts in oven temperature or humidity at the day of drying. The solution can be as simple as extending a vacuum stage or double-checking the rinse on a filter press, but we always implement fixes upstream, safeguarding future batches.

    Counterfeit and diluted materials pose an increasing risk, especially on global exchanges where rebranding and mixed sourcing occur. We’ve responded by offering direct support and verifiable analytics, including batch-signed NMR, MS and elemental data. For researchers with strict regulatory requirements, our documentation follows the product, not just the order number, so they close out compliance audits with evidence, not generic certificates.

    Actual Customer Stories

    One European client in the agricultural sector ran years of field trials on active compound libraries. They reported swings in performance linked to inconsistent input material. Our product maintained not just purity but also minimized polymorphic variance across the seasons, eliminating the annual retesting cycles forced by suppliers with shifting quality.

    Another customer in specialty electronics ran solvent-vapor compatibility checks. Trace impurities in off-the-shelf grades caused shifts in sensor calibration. Once our lot-controlled material entered the workflow, their error rates dropped, saving months in validation work. These kinds of results aren’t accidental, and they don’t follow from faceless sourcing; they arise through direct relationships between user feedback and production choices in our plant.

    What Drives Our Manufacturing Decisions

    Scalability isn’t just about producing more tons per year. As production volumes grow, mistake tolerance shrinks. We document changes in every procedure so that increased demand never comes at the cost of predictability. If a compound is sensitive to oxygen during transport, we make sure the packaging includes oxygen-absorbing liners. If certain storage conditions cause crystallization drifts, we share those precautions upfront and ask for real-world feedback to monitor material health after delivery.

    Fielding technical questions directly from users has revealed pain points we’d never spot from a distance. One partner flagged an unexpected discoloration after months in warehouse storage — our tests linked it to a reaction between the product and certain package adhesives under humid conditions. The fix required not just changing materials, but re-certifying storage partners and adding an extra QC checkpoint. This cycle repeats itself across years, with constant iteration.

    Future Direction and Continuous Improvement

    We never treat our process as finished. Market needs and available technologies change fast, and every shift in customer workflow can challenge assumptions about how a chemical is made, handled, and stored. Our R&D team keeps lines open with both buyers and the operators who use these chemicals daily. When better purification options or energy-saving reaction alternatives emerge, we assess them in house, testing against proven applications before full rollout.

    Open conversations guide our investments — better instrumentation, safer handling methods, or additional training for plant staff. Adjustments like upgrading reactor materials, automating more steps in isolation or even doubling up on raw material analytics aren’t just compliance-driven, they’re practical steps to preventing the headaches that come from hidden variability. Unlike hands-off traders, we adapt every cycle based on user data, keeping the chain from process chemistry all the way through finished application as short and transparent as possible.

    Building Confidence in Every Shipment

    Any high-value synthesis benefits or fails based on the raw materials chosen. For us, each batch of 6-oxo-1,6-dihydropyridine-3-carboxylate that leaves the facility represents hundreds of decisions about sourcing, technology and quality. Our partnerships grow out of the trust that comes from product, documentation and technical conversations, not just an order form. By keeping every aspect of manufacturing in house — from raw material validation and synthesis through purification, drying and packaging — we bring a consistency to supply that’s impossible to match through intermediaries. With customer experience shaping every step of our operation, what arrives at your facility is more than a chemical, it’s the result of a deliberate, transparent manufacturing process built for scientific progress.