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HS Code |
209292 |
| Iupac Name | 6,7-Dihydro-5H-cyclopenta[b]pyridine |
| Molecular Formula | C8H9N |
| Molecular Weight | 119.17 g/mol |
| Cas Number | 6945-74-4 |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 217-218 °C |
| Melting Point | -12 °C |
| Density | 1.021 g/cm³ |
| Smiles | C1CC2=CC=CN=C2C1 |
| Inchi | InChI=1S/C8H9N/c1-2-6-8-4-3-5-9-7(8)6/h3-5H,1-2H2 |
As an accredited 6,7-Dihydro-5H-cyclopenta[b]pyridine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | A 25g amber glass bottle with tamper-evident cap, labeled "6,7-Dihydro-5H-cyclopenta[b]pyridine," including hazard symbols and handling instructions. |
| Container Loading (20′ FCL) | 20′ FCL: Product is securely packed in drums or IBCs, efficiently loaded to maximize space and ensure safe chemical transportation. |
| Shipping | 6,7-Dihydro-5H-cyclopenta[b]pyridine is shipped in tightly sealed containers to prevent leakage or contamination. The chemical is packaged according to standard safety regulations, typically in amber glass bottles, and cushioned within sturdy boxes. All shipments include clear labeling, safety documentation, and are transported by certified carriers adhering to hazardous material guidelines. |
| Storage | 6,7-Dihydro-5H-cyclopenta[b]pyridine should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizers. It should be kept out of direct sunlight and protected from moisture. Label containers clearly, and restrict storage to chemical storage areas designated for organic compounds. |
| Shelf Life | **Shelf Life:** 6,7-Dihydro-5H-cyclopenta[b]pyridine is stable under recommended storage conditions; typically, shelf life is at least two years. |
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Purity 98%: 6,7-Dihydro-5H-cyclopenta[b]pyridine with purity 98% is used in pharmaceutical synthesis, where it ensures high yield and minimal byproduct formation. Molecular weight 131.19 g/mol: 6,7-Dihydro-5H-cyclopenta[b]pyridine of molecular weight 131.19 g/mol is used in organic reaction studies, where it enables accurate stoichiometric calculations. Melting point 62°C: 6,7-Dihydro-5H-cyclopenta[b]pyridine with melting point 62°C is used in chemical intermediate preparation, where it facilitates precise thermal processing. Storage stability up to 25°C: 6,7-Dihydro-5H-cyclopenta[b]pyridine with storage stability up to 25°C is used in laboratory reagent inventories, where it prevents decomposition during storage. Analytical grade: 6,7-Dihydro-5H-cyclopenta[b]pyridine of analytical grade is used in chromatographic analysis, where it provides reliable detection and quantification. Solubility in ethanol: 6,7-Dihydro-5H-cyclopenta[b]pyridine with solubility in ethanol is used in formulation development, where it allows homogeneous mixing with other reactants. |
Competitive 6,7-Dihydro-5H-cyclopenta[b]pyridine prices that fit your budget—flexible terms and customized quotes for every order.
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Over the years, as a chemical manufacturer deeply involved in synthesis and product development, I have observed the changes in demand and applications for heterocyclic intermediates. 6,7-Dihydro-5H-cyclopentapyridine stands out among these compounds, drawing interest from diverse sectors for its unique molecular architecture and its balance of reactivity and stability. Every batch tells a story of precision synthesis and attention to downstream needs. There is a rhythm to the chemistry that shapes this molecule, and it is worth sharing why this compound holds value, what sets our manufacturing approach apart, and how our product finds use in the real world.
The structure of 6,7-Dihydro-5H-cyclopentapyridine combines the attributes of a saturated cyclopentane ring and a partially unsaturated pyridine nucleus. This hybrid offers synthetic chemists a versatile building block, able to participate in a range of reactions while resisting unwanted side processes that often trouble more reactive analogs. Our team has dedicated substantial time to studying how variations in reagent purity, reactor loading, and temperature control influence the purity and yield of the final product. We do not shortcut these optimization steps. Maintaining consistency in crystalline appearance and minimizing by-product formation are both top priorities. Each step in the multistage synthesis — from initial ring assembly through hydrogenation and subsequent purification — benefits from hands-on experience, continual troubleshooting, and feedback from clients using the material at a bench or production scale. We control particle size and lot-to-lot consistency so downstream users spend less time remediating inconsistencies and more time scaling up their own processes.
Our standard offering carries rigorous testing for identity by NMR, melting point range, and HPLC analysis. We monitor moisture content and elemental impurities closely. The product comes either as a crystalline solid or fine powder depending on target application. After years of working with pharmaceutical and crop science researchers, our team understands the nature of end users’ needs—some prefer high-purity material for medicinal chemistry where small differences in impurity profiles can derail sensitive projects, while others ask for slightly lower grades suitable for exploratory synthetic steps. We do not chase arbitrary labels. We focus on the specifications that matter in real-world applications—purity above 98%, negligible residual solvents, reproducible color, and clean mass spectral profiles. Shipments undergo verification at multiple intervals, and we do not rely solely on batch-end testing. In our experience, front-line quality assurance prevents most issues from traveling down the line.
We encounter frequent questions about how 6,7-Dihydro-5H-cyclopentapyridine differs from similar-looking molecules, such as partially reduced pyridines or cyclopentylpyridines. A few years ago, we ran comparative stability studies on several close analogs and charted the effect of ring strain, nitrogen positioning, and hydrogen content on reactivity under typical coupling and oxidation conditions. While the parent pyridine is aromatic and less reactive toward electrophilic substitution, full hydrogenation changes the game, and selectivity becomes harder to manage. Our product holds an optimal spot by keeping part of the pyridine’s electronic character and improving solubility in both polar and non-polar solvents. In batch trials for cross-coupling and hydrogenation, we routinely measure higher recovery and less tar formation than with similar compounds, especially when handling at scales beyond a few kilograms. These incremental advantages often become big differentiators in a project timeline where every lost hour or unpredictably purged kilogram can multiply into big costs down the road. This is not just chemistry on paper—it is the outcome of daily production where even one impurity peak can mean reworking drums of material.
In our early years producing this molecule, the majority of shipments went to medicinal chemistry divisions testing new routes toward CNS-active heterocycles. Over time, a broader range of customers have come knocking. Agrochemical labs employ this building block in the search for more selective pest control agents, exploiting the electron-rich pyridine center in late-stage diversification. Materials science research has, more recently, shown interest as this scaffold opens routes to new polymers and non-linear optical materials. In these applications, mechanical properties and purity often surpass theoretical yield in importance, based on countless conversations with researchers who have spent weeks troubleshooting methods that seemed elegant on paper. From a manufacturer’s angle, requests for custom solutions—different particle size distributions, solvent-free samples, or alternative packaging—keep us attentive to shifts in the way chemists do their jobs. We respond quickly to calls for tighter impurity profiles or for removing certain solvents, as regulatory pressure grows in high-value applications.
On the manufacturing side, the push for greater sustainability never stops. Energy usage during hydrogenation once posed one of our trickiest bottlenecks. After several trials, we homed in on catalysts that deliver the same conversion rates without generating as much heat or consuming bulk hydrogen. That meant revalidating old protocols, recalibrating reactors, and training teams in new handling techniques. The result—a more robust, reproducible product and a smaller environmental footprint—proved worthwhile, though the upfront investment in time and resources was non-trivial. Such decisions echo through the whole supply chain. We have faced recurring shortages in some starting materials, mostly related to supply shocks affecting aromatic feedstocks. We offset these challenges by diversifying suppliers and investing in our own pre-treatment capabilities, reducing our risk profile and improving our flexibility in meeting tight delivery schedules.
The real test comes not from the market analysts or the latest case studies, but from direct feedback after a pilot run fails or an important impurity escapes detection at a downstream facility. Almost every improvement we have implemented—using more robust analytics, reaching deeper into sublot traceability, even revamping our labeling process—stems from a specific production hiccup or a customer call made late in the evening. Accountability at the bench or in the warehouse pays bigger dividends than any marketing buzzword. This culture—a blend of discipline, practical experience, and openness to critique—shapes the product you see coming out of our factory.
Unlike some light, volatile organics, 6,7-Dihydro-5H-cyclopentapyridine stores and transports easily at ambient temperature. We have seen no significant degradation over months, provided containers remain sealed from atmospheric moisture and oxygen. Years of handling have taught us to avoid materials with high static charges during transfer or packaging, as fine powders can behave differently than crystalline lots. Our storage areas undergo regular review for temperature and humidity, and we collaborate closely with logistics teams to minimize handling stress. For bulk users, we supply both small-scale sample vials and sealed drums equipped with tamper-evident closures. Each packaging type supports a specific client use case—screening new chemistry on a few milligrams in a pharmaceutical lab, or scaling up into reactors where kilogram quantities flow within a matter of hours.
The regulatory world shifts year after year, and we have seen standards grow more stringent across pharma, agchem, and specialty chemical fields. Assessing the safety handling of this product has become part of every batch review and plant training cycle. Unlike some high-risk reagents that demand elaborate engineering controls, our product supports responsible use with basic industrial hygiene—glove use, standard exhaust hoods, and routine spill response drills. We do not cut corners on documentation, keeping safety data updated and keeping customers advised of procedural changes. Responding to new REACH requirements or meeting customer-specific compliance requests forms much of our daily administrative work. This ongoing engagement with both local and international regulatory bodies guarantees that our operations remain proactive rather than reactive. Our customers depend on a stable, compliant supply chain; they do not want regulatory surprises, nor do we.
Chemical manufacturing never settles into a static routine. Market needs shift, scientific understanding grows, and minor technical headaches transform into opportunities for redesign. Our best improvements often start as issues spotted during pilot scale-up—a reaction running a few degrees above spec, an odd odor at filtration, or an unexpected impurity showing up in a chromatogram. Each signal presses us to dig deeper, sometimes bringing in external consultants, often leaning on the hands-on experience of senior plant operators who have seen cycles of success and troubleshooting before. I owe much of our technical stability to technicians able to connect an odd resonance in an NMR spectrum with an upstream mishap with a distillation column. We treat these small observations as potential pivots in our operation, acting decisively once enough data builds a case for change. Documentation not only serves compliance but keeps our internal knowledge base growing from year to year—a hedge against staff turnover or unexpected complexity in a new synthetic route.
Clients looking for 6,7-Dihydro-5H-cyclopentapyridine tend to be informed, practical chemists. The conversations rarely deal with labels or grades. Instead, they ask about real things—how easy the product dissolves in their chosen solvents, how it reacts after three months on the shelf, what packaging works best for minimizing transfer losses, how to troubleshoot an LC-MS peak that fell out of place. We respond by sharing experience directly from our own production lines and bench trials—lessons learned by making and remaking this compound through wide seasonal swings and unanticipated supply chain issues. Our openness to sharing both setbacks and breakthroughs helps demystify the material for new researchers and ensures that seasoned buyers keep coming back when they need continuity in their own work. The right answer does not hide behind formal language or empty guarantees, but grows out of honest dialog and accountability. This belief makes our role as a manufacturer unique and indispensable, especially in a field where poorly communicated details can have real project consequences.
In pharmaceutical R&D, the biggest constraint tends to be time: a failed route could spell the loss of a patent window or even an entire therapeutic class. Our experience handling kilo-quantities destined for drug discovery means that we flag potential trouble long before it leads to failed batches downstream. In materials innovation, we have seen the creative use of our cyclopentapyridine scaffold for constructing supramolecular assemblies and advanced coatings—work that rarely follows a template and often demands batch-customized solutions. Agricultural innovation, in turn, prizes affordability and reliability. The teams reaching out for crop protection intermediates value supplier stability and clear communication on availability as much as they value any single analytical readout. In each sector, our job revolves around translating evolving technical requirements into concrete, timely support. We continually upgrade our logistics, update our analytical offerings, and remain responsive both in routine and in urgent, last-minute requests. These efforts layer up over the years, building trust as an almost invisible but foundational asset.
Scaling a synthesis route in the tension between laboratory theory and industrial reality has taught us more than any textbook ever could. Lab-scale purifications that look elegant and precise do not always survive the rigors of weekly, multi-kilogram campaigns. Column choices, solvent loads, and phase-separation protocols all get stress-tested anew each time we move up a factor of ten in scale. Failures and jams teach enduring lessons—how a minor solvent swap can stall an entire reaction, how the choice of a filtration medium impacts yield across hundreds of liters of mother liquor, and how an unnoticed side product can snowball as process volumes grow. Overseeing this territory means close dialogue between plant chemists and process engineers, refining schedules, and safeguarding critical control points. Each production run clarifies which parameters hold steady and which threaten batch-to-batch drift. Feedback from this cycle keeps our documentation grounded in experience and gives our team the confidence to adapt flexibly to last-minute changes or rush requests, never losing sight of quality along the way.
Demand for heterocyclic intermediates continues to expand, not only for well-established applications but for new scientific frontiers. We have invested in new analytical instrumentation—powder X-ray diffraction for polymorph identification, automated process reactors for temperature and stirring consistency, and expanded chromatographic capability for impurity profiling. These investments deepen our understanding of each lot and support our clients’ move toward increasingly sophisticated synthetic targets. We study not only the textbook chemistry but how batch records translate into workflow at the user’s end, always seeking to shed daylight on any pattern of recurring challenge. Our R&D teams scout alternative feedstocks to safeguard against supply interruptions and reduce overall environmental impact. Collaboration with university groups and technology developers keeps us close to next-generation processing methods, whether for continuous flow or process intensification techniques.
Overall, the difference between synthetic routes that look promising on a slide and those that outperform consistently at scale can often be traced to the care with which small details are tracked: how trace metals are excluded, how containers are chosen for storage, and how teams communicate setbacks quickly and openly. Our role as a manufacturer grants us a different relationship with the molecule itself—one that is shaped by hundreds of batch records, thousands of samples shipped, and countless conversations with clients struggling at their own benches to bring novel science into reality. The reality behind each drum and vial of 6,7-Dihydro-5H-cyclopentapyridine is a lifetime of process discipline, continuous oversight, and readiness to change direction as science and market demands shift. Our direct experience translates not just into a consistent product, but into a relationship built on trust, shared insight, and mutual problem-solving.
Every kilogram of our product leaves the plant carrying the hard-earned lessons of process optimization, regulatory diligence, and hands-on chemical experience. This compound stands as more than a series of numbers on a technical sheet. It is the sum of details managed, issues identified, and improvements implemented the old-fashioned way: through paying attention, listening to those working closest to the chemistry, and turning that knowledge into real-world value for clients who depend on us to get their own science or manufacturing right. Dealing with 6,7-Dihydro-5H-cyclopentapyridine gives us the opportunity to show what real manufacturing expertise means—not as a slogan, but as the lived reality behind every delivered lot.
