5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine

    • Product Name: 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine
    • Chemical Name (IUPAC): 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine
    • CAS No.: 218144-65-9
    • Chemical Formula: C15H16N2O3
    • Form/Physical State: Solid
    • Factroy Site: No.968 Jiangshan Rd., Nantong ETDZ, Jiangsu, China
    • Price Inquiry: sales7@boxa-chem.com
    • Manufacturer: Nantong Acetic Acid Chemical Co., Ltd.
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    Specifications

    HS Code

    351061

    Chemical Name 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine
    Molecular Formula C15H16N2O3
    Molecular Weight 272.3 g/mol
    Appearance Yellow solid
    Boiling Point Decomposes before boiling
    Melting Point 85-87°C (lit.)
    Solubility Soluble in DMSO, slightly soluble in ethanol
    Storage Conditions Store at room temperature, keep away from light

    As an accredited 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 25 grams of 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine, tightly sealed, labeled with hazard warnings.
    Container Loading (20′ FCL) Container Loading (20′ FCL): Securely packs 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine in 20′ containers, ensuring safe, compliant bulk shipment.
    Shipping **Shipping Description (approx. 50 words):** 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine should be shipped in tightly sealed containers, protected from light, moisture, and physical damage. Label as a laboratory chemical. Follow all relevant ADR/IATA regulations. Ensure compatibility of packaging with nitro compounds. Ship at ambient temperature unless otherwise specified. Include material safety data sheet (MSDS) and hazard information with the package.
    Storage 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from sources of ignition and incompatible materials such as oxidizers, acids, or strong bases. Protect from light and moisture. Store at ambient temperature, and label the container appropriately. Always follow standard chemical safety and storage protocols.
    Shelf Life Shelf life: **2 years** under cool, dry conditions in tightly sealed containers, protected from light and moisture for optimal stability.
    Application of 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine

    Purity 99%: 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine with 99% purity is used in pharmaceutical intermediate synthesis, where it ensures high product yield and limited by-product formation.

    Molecular weight 284.32 g/mol: 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine of molecular weight 284.32 g/mol is used in specialty chemical research, where accurate stoichiometric calculations and predictable reaction pathways are achieved.

    Melting point 92°C: 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine with a melting point of 92°C is used in solid-state formulation development, where thermal stability and ease of processing are prioritized.

    Stability temperature up to 120°C: 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine stable up to 120°C is used in high-temperature material syntheses, where product integrity is maintained under reaction conditions.

    Particle size <10 µm: 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine with particle size below 10 µm is used in advanced coatings, where improved dispersion and uniform surface finish are required.

    Solubility in DMSO >100 mg/mL: 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine with solubility over 100 mg/mL in DMSO is used in biochemical assay development, where high concentration preparations and consistent result reproducibility are attained.

    Residual solvent <0.5%: 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine with residual solvent content below 0.5% is used in electronics manufacturing, where low impurity levels enhance device reliability and safety.

    UV absorbance λmax 312 nm: 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine with UV absorbance maximum at 312 nm is used in analytical reference standards, where sensitive detection and accurate quantification are necessary.

    Free Quote

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    Certification & Compliance
    More Introduction

    Introducing 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine: Reliable Performance from a Committed Manufacturer

    Real Value from Direct Chemical Manufacturing

    Few in the chemical industry get to watch a compound take shape, step after step, batch after batch. We do. As a chemical manufacturer specialized in pyridine derivatives, we have handled 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine since its early development. Our technicians know every nuance of the process, from raw materials sourcing to crystallization, filtration, and purification. If the feedstock’s moisture changes, we see it. If the reaction drifts off optimal temperature, our system shows us right away. That hands-on manufacturing brings consistency and clarity, from the first kilogram to multi-ton capacities.

    Technical Profile and Batch Integrity

    Each manufacturing run begins with a fresh evaluation of raw input streams. No two chemical syntheses run identical, and tight raw materials control protects downstream purity. Our standard 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine model carries a minimum assay above 98%. Analytical HPLC and NMR confirmation removes speculation. Nitrate residue and color-forming impurities stay tightly bounded by our own specifications—not copied from a trader’s certificate, but validated in our in-house QA lab.

    Formed as a light yellow to off-white crystalline solid, the product’s melting point lands in a narrow, predictable range. The particle size distribution results directly from our own crystallization profile control; drying parameters are not an afterthought, but a controlled process stage. Each batch comes sealed in custom-lined containers, with vapor barrier liners to mitigate moisture ingress—critical especially in humid climates. Warehouse managers tell us this sharply reduces caking, dust loss, and off-odors, preserving material quality on site.

    Application-Based Production

    Over years of supporting downstream users, many applications for 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine have come into focus. Most prominently, it serves as a tailored intermediate for pharmaceutical synthesis, particularly in research and pilot-scale routes relying on functionalized pyridines. Our customers are not just catalogue buyers; they represent process teams and lab managers who need consistent conversion yields, minimal re-purification, and reliable performance when scaling up.

    Laboratory feedback highlighted specific functional group sensitivity during alkylation and ether cleavage—impurities can wreck yields and force extra purification steps. Tweaking our process parameters, such as fine-tuning solvent polarity and reaction sequence, delivered a purer material that slotted easily into these advanced synthesis routes. We did this not to shave pennies, but to save our customers hours of rework.

    Specialty coatings makers periodically request this pyridine variant for its molecular stability and performance in harsh environments. Their demands include strict control over trace contaminant levels, which often means introducing additional purification steps at the final stage. Adapting production runs to meet these stricter requirements builds a collaborative relationship and a genuine feedback loop, rather than just offering off-the-shelf material and waiting for complaints to roll in.

    Real Differences from Market Alternatives

    It often surprises buyers how wide the quality spectrum runs in specialty chemicals sold under a single name. Shortcuts become visible under close scrutiny. Batch-to-batch impurity variation, inconsistent moisture levels, and haphazard packaging each add risk downstream. Resellers or traders can source material from different origins, each with unique byproduct profiles that slip past standard certificates.

    Our material’s main difference comes from vertical integration: we run synthesis, work-up, and packaging in-house. Unlike brokers who combine anonymous sources, we trace every production run back to the raw materials lot, with a complete analytical record for each. This consistent supply offers peace of mind to R&D managers and production supervisors who must predict process performance months in advance.

    Another marked difference lies in how we respond to end-use feedback. Process changes needed for API pathway modifications or new regulatory requirements get discussed directly with chemists on our floor. Thanks to this immediacy, our product can shift in response—adjusting solvent choices to lower halogen content, or upgrading drying capability for more arid storage. These aren’t theoretical claims; they stem from real process modifications made when our partners needed stronger assurance.

    Direct Manufacturing Accountability

    Being a manufacturer does not just mean producing molecules; it means assuming the risks, rewards, and responsibilities of putting your name to the chemistry. We accept full accountability for each container shipped out of our doors. Our technical team stands ready to troubleshoot any anomaly—not deflect blame down the supply chain, but fix it at the source.

    A common complaint with channel intermediaries revolves around slow feedback and finger-pointing if a quality issue appears. Our customers know who to call because their technical contact often witnessed the batch’s final approval. Rather than quoting specification sheets, we send analytical results on request, offer production samples, and retain batch reference material to resolve future questions without delay.

    Quality Control Practices Informed by Experience

    Quality means little if it exists only in slogans. In our lab, every operator sees the real consequences of minute process shifts. Even a subtle contaminant spike can trigger downstream chromatogram interference or unpredictable color formation during a pharmaceutical coupling reaction. To prevent these, our QA team profiles not just the main product but all trace-level byproducts, using GC-MS, LC-MS, and NMR.

    Long-term storage stability also depends on eliminating reactive trace solvents and metal ions. To reach the demands of pharmaceutical syntheses, we implemented facility-wide solvent recycling and oxygen control for sensitive synthesis steps. This not only decreased the count of potential unknowns but also improved overall yield consistency. Our packaging department rigorously double-bags hygroscopic batches and minimizes exposure to ambient air, pre-emptively addressing issues that often appear during cross-country shipping or long-term storage.

    Documented root-cause analysis happens with any deviation, no matter how minor. Every time an issue—such as minor coloration or unexpected impurity—arose, we found a cause, corrected it at the source, and adjusted our process documentation. This discipline builds reliability batch after batch, supported by retained samples and validated testing protocols.

    Supporting Changing Industrial Needs

    Regulatory frameworks evolve, and so do raw material standards. Reach or export regulations can refine expected impurity lists on short notice. When new reporting becomes necessary, such as detailed impurity profiles or expanded MSDS data, we generate the requested documentation from our process history—rather than wait for combined reports from third-party labs. Each dataset comes straight from our own instruments, interpreted by technicians who understand more than just numbers.

    Adjusting to market or environmental shifts requires flexibility. Over the last decade, our sourcing department sought out more sustainable, less hazardous precursors when feasible. This sometimes increases production cost or requires upstream process tweaks, but it also delivers greater stability in supply and a lower environmental footprint—a tangible improvement we believe matters to both end users and the communities nearby.

    Collaboration between production, processing, and packaging teams ensures that every step—from raw material handling to product delivery—is guided by real people with long-standing expertise in pyridine chemistry, not abstract procedures or impersonal outsourcing.

    Practical Uses, Insights, and Limitations

    Most inquiries for 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine come from process chemists and scale-up researchers. They bring practical concerns: reliability under process conditions, safe handling in plant settings, and consistency when moving from gram-scale to larger syntheses. We don’t presume to dictate applications, but share the common threads: pharmaceutical research, pilot testing for custom intermediates, and evaluation as an intermediate in agrochemical and specialty materials studies.

    Certain users have tried adapting the compound for advanced material applications—such as specialty electronic coatings or ion-conductive membranes—where narrow impurity control becomes especially critical. In these scenarios, we draw on our existing purification expertise, often working alongside customer labs to target specific contaminants or optimize handling protocols. This hands-on feedback cycle helps both us and our partners spot issues early and save resources over time.

    Material limits do apply. The nitrophenoxy group, while enhancing molecular reactivity, can increase sensitivity to reduction or photochemical degradation under aggressive process conditions. We share degradation data and storage advice openly rather than overstating stability. End-users with unique conditions—unusual temperature cycling, long shelf life, or direct light exposure—get real numbers and mitigation practices, not marketing assurances.

    We stay away from promising applications that fall outside demonstrated capabilities. If a chemical’s performance in a high-energy, long-term stability role has not been confirmed, we say so openly. Our reputation has grown among direct manufacturers and advanced R&D groups less because of high-volume sales, and more from an honest approach to product strengths, weaknesses, and real-world testing.

    Looking at Market Shifts

    Over the last few years, the specialty chemical space changed dramatically. Global supply disruptions and regulatory shifts reshaped availability. Customers have shared experience with supply interruptions or ambiguous paperwork stemming from multi-tiered sourcing. As direct manufacturers, we witnessed increased value placed on traceable origin, verified documentation, and open technical dialogue about product characteristics.

    In response, we streamlined supply chain management and enhanced digital traceability across each manufacturing step. Each 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine batch now carries an electronic production certificate detailing lot-level raw material data and testing results. This supports fast regulatory compliance, border crossing, and the kind of forensic batch analysis that builds long-term trust.

    With changes in energy pricing, raw material shifts, and greener chemistry imperatives, production managers and procurement officers increasingly want both value and transparency. Direct feedback from customers continues shaping our scheduling, purity targets, and delivery options—creating real two-way accountability. This philosophy, prioritizing responsiveness over volume-driven output, sets apart our approach to every kilogram shipped.

    Experience at Every Scale

    Supplying gram to multi-ton quantities offers a learning curve visible nowhere else. Small-batch, high-purity needs from a pharmaceutical lab require isolation from cross-contamination, often using separate lines or dedicated glass-lined reactors. Larger volumes, common for specialty material producers, emphasize logistics and container quality, maintaining product properties across long shipping routes and extended storage periods. Each process is run with traceable quality steps embedded—not retroactively added for appearance, but baked into daily practice.

    Adapting our manufacturing to customer scale means more than ticking off logistics tasks; it is about direct technical engagement for dosing, solubility, and operator handling. Sometimes, a large customer’s plant trial exposes an issue unseen in laboratory use, such as a new compatibility challenge, or subtle differences in filtration or transfer. Our technical group often travels to gather direct, on-site feedback, applying those findings to tweak drying cycles, adjust crystalline forms, or re-assess packaging protection.

    Nothing replaces first-hand visibility over synthesis and quality control. This embedded experience gives process chemists and plant managers confidence—knowing direct answers are available for any question or concern, with product attributes grounded in actual production facts, not generalized standards.

    What Quality Means for Us—and for You

    Over decades, we have learned what “good chemical quality” actually means: proven batch control, open communication, and the continual push for real improvement. 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine is not just an item on a list—it is a product that changes with each innovation in chemistry, each customer trial outcome, each shift in market demand. Our team builds those lessons into every kilogram, every time.

    Some competitors boast of being suppliers, but few serve as real partners in supporting applications, adapting processes, and delivering practical documentation. Regular audits, continuous operator training, error analysis, and retention of batch material enable us to guarantee what we make. As a manufacturer, our responsibility centers not just on “meeting spec” but on owning the real-world outcomes that come from long-term customer use.

    We base our promise on what we know and what our customers have taught us. Each request, each challenge, and each shipment gives us another lesson. We pass that assurance and accumulated knowledge to every user of our 5-ethyl-2-[2-(4-nitrophenoxy)ethyl]pyridine—making it a reliable partner in innovation, efficiency, and everyday chemical manufacturing.