4-pyridinemethanamine, 3-chloro-

    • Product Name: 4-pyridinemethanamine, 3-chloro-
    • Chemical Name (IUPAC): (3-chloropyridin-4-yl)methanamine
    • CAS No.: 148217-38-1
    • Chemical Formula: C6H7ClN2
    • Form/Physical State: Solid
    • Factroy Site: No.968 Jiangshan Rd., Nantong ETDZ, Jiangsu, China
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    • Manufacturer: Nantong Acetic Acid Chemical Co., Ltd.
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    Specifications

    HS Code

    169301

    Chemical Name 4-pyridinemethanamine, 3-chloro-
    Molecular Formula C6H7ClN2
    Molecular Weight 142.59 g/mol
    Cas Number 39546-32-2
    Iupac Name 1-(3-chloropyridin-4-yl)methanamine
    Appearance solid
    Solubility Soluble in water and organic solvents
    Smiles NCc1ccncc1Cl
    Inchi InChI=1S/C6H7ClN2/c7-6-3-5(4-8)1-2-9-6/h1-3H,4,8H2

    As an accredited 4-pyridinemethanamine, 3-chloro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 100g package features a labeled amber glass bottle, securely sealed, displaying "4-pyridinemethanamine, 3-chloro-" and appropriate hazard symbols.
    Container Loading (20′ FCL) Container Loading (20′ FCL) for 4-pyridinemethanamine, 3-chloro- ensures secure, efficient bulk shipment in 20-foot full container loads.
    Shipping Shipping for 4-pyridinemethanamine, 3-chloro- requires secure packaging in compliance with chemical transport regulations. The substance should be stored in tightly sealed containers, clearly labeled, and protected from moisture and incompatible materials. Shipping must follow all applicable local and international hazardous materials guidelines to ensure safe delivery and handling.
    Storage 4-Pyridinemethanamine, 3-chloro-, should be stored in a tightly sealed container in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizing agents. Keep away from direct sunlight and moisture. Ensure the storage area is clearly labeled and access is limited to trained personnel. Use secondary containment to prevent spills.
    Shelf Life Shelf life of 4-pyridinemethanamine, 3-chloro- is typically 2-3 years when stored cool, dry, and protected from light.
    Application of 4-pyridinemethanamine, 3-chloro-

    Purity 98%: 4-pyridinemethanamine, 3-chloro- with a purity of 98% is used in pharmaceutical intermediate synthesis, where it ensures high yield and minimal by-product formation.

    Melting Point 72°C: 4-pyridinemethanamine, 3-chloro- with a melting point of 72°C is used in custom chemical synthesis, where it provides controlled processing conditions and reproducible crystallization.

    Molecular Weight 156.6 g/mol: 4-pyridinemethanamine, 3-chloro- with a molecular weight of 156.6 g/mol is used in structural elucidation studies, where it enables accurate stoichiometric calculations in formulations.

    Solubility in Methanol 50 g/L: 4-pyridinemethanamine, 3-chloro- with solubility in methanol of 50 g/L is used in homogeneous catalysis research, where it permits efficient reagent mixing and improved reaction rates.

    Stability Temperature up to 120°C: 4-pyridinemethanamine, 3-chloro- with stability up to 120°C is used in heat-driven chemical processes, where it maintains chemical integrity during elevated temperature reactions.

    Particle Size <10 μm: 4-pyridinemethanamine, 3-chloro- with particle size less than 10 μm is used in fine chemical manufacturing, where it ensures uniform dispersion and high surface reactivity.

    Water Content <0.2%: 4-pyridinemethanamine, 3-chloro- with water content below 0.2% is used in moisture-sensitive synthesis, where it reduces hydrolysis risk and improves final product consistency.

    Assay >99%: 4-pyridinemethanamine, 3-chloro- with assay greater than 99% is used in analytical reference standards, where it guarantees precision and reliability in quantitative analytical methods.

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    Certification & Compliance
    More Introduction

    Introducing 4-pyridinemethanamine, 3-chloro-: A Reliable Companion for Chemical Advancements

    Everyday Science, Everyday Solutions

    Sometimes it’s easy to overlook the actual labor and curiosity at play behind a name like 4-pyridinemethanamine, 3-chloro-. In the lab or factory, this compound isn’t some abstract idea. Researchers see it as a tool that can open the door to new syntheses or treatments, and chemists value its reliability and clear structure. For those diving into pharmaceutical, chemical, or material science projects, this product often finds a place right on the shelf—its C6H7ClN2 backbone giving teams a starting point for many lines of inquiry.

    Formulating with Precision

    Not every intermediate receives as close of a look as 4-pyridinemethanamine, 3-chloro-. Its single substitution—chlorine on the third position of the pyridine ring—sets its behavior apart from related compounds. In practice, this altered structure often leads to opportunities for researchers needing something other than what plain pyridinemethanamines provide. Small changes in molecular structure sometimes produce big results. This isn’t just textbook chemistry; it’s a reality that can shape the success or slog of entire projects.

    Through years of handling these types of compounds, one thing becomes clear: a stable amine with an accessible functional group allows for versatile downstream reactions. In the past, colleagues have turned to 4-pyridinemethanamine, 3-chloro- due to its knack for forming strong bonds with other molecules—especially where a different substituent would bring less reactivity. This matters whether you’re building out therapeutic candidates in pharmaceutical settings or customizing ligands for catalytic studies.

    Quality in Research Matters

    I’ve seen projects stall because the quality of starting materials didn’t measure up to what the reaction demanded. One trusted manufacturer once told me, “Consistency isn’t optional, it’s everything.” Over time, I’ve found it’s worth investing in highly pure inputs, and 4-pyridinemethanamine, 3-chloro- is no exception. Researchers benefit from a clearly defined melting point, a narrow impurity profile, and ease of handling. Relying on a product with known characteristics turns variables into constants, allowing teams to focus on the next step instead of troubleshooting contamination or batch-to-batch variability.

    The product often arrives as a solid, which reduces the kind of volatility or handling worries found in liquids or powders that scatter easily. Experienced hands recognize the importance of that seemingly small detail. Products that offer manageable storage conditions and a reasonable shelf life free up time and resources—not just for one project, but also for organizations managing multiple research pipelines.

    Comparing Chemical Pathways: Why Structure Affects Success

    Every time a team must pick between similar intermediates, small chemical nuances carry substantial weight. Chemists often stack the 3-chloro version of pyridinemethanamine against the non-chlorinated variant or those substituted on different positions of the ring. The placement of chlorine changes the electron density and thus modifies how the amine group can participate in further transformations. In my experience, this can spell the difference between a time-intensive purification step and a clean, single-path reaction.

    Think of a case where a catalytic process favors electrophiles. The presence of a chlorine group can steer reactivity in a way that enhances selectivity. Over the years, more labs have noted that derivatives built from this product end up carrying improved binding or metabolic profiles in early-stage biological tests. While “big results” depends heavily on the context, the bottom line remains: structural shifts, no matter how minor, sometimes unlock whole new avenues of exploration.

    Application in Practice

    Some might ask if a compound like this has any real effect beyond chemistry’s theoretical boundaries. In fact, its usage threads through real-world problems. Pharmaceutical development often relies on modifications to established scaffolds. For instance, swapping out a hydrogen for a chlorine atom in the precursor gives medicinal chemists a way to tweak bioavailability or target engagement in drug candidates. A good number of development portfolios feature molecules where thoughtful addition of a group made a candidate viable.

    Outside medicines, this product holds value in agrochemical and polymer innovation. With crops facing pressure from climate and pests, even incremental changes to protective agents make a tangible difference. The ability to attach a substituted amine like 4-pyridinemethanamine, 3-chloro-, often allows agrochemical formulators to dial in efficacy and persistence. The broader materials space also benefits from such targeted modifications. Logbooks in many research centers have records filled with experiments where this precise substitution determined polymer branching, thermal stability, or electrical properties.

    Why A Trusted Source Matters

    Many labs share a quiet joke about how even the best plans can fall apart due to one back-ordered starting material. Having moved through multiple research and production stages myself, dependable supply chains are non-negotiable. It’s frustrating to face dashboards full of red warnings because the only batch available doesn’t match the necessary purity or is stuck in customs. Teams looking past the next experiment take time to confirm their material’s origin, check for a transparent certificate of analysis, and look to providers with positive feedback or long-term relationships in the scientific community.

    I remember a certain scale-up that only worked because we had access to a reliable supply of 4-pyridinemethanamine, 3-chloro-. The project might not have survived repeated delays without that resource on hand. For those managing startup budgets or facing high-stakes delivery schedules, confidence in the consistency of chemicals like these saves not only money, but also reputation.

    Addressing Common Challenges and Setting Expectations

    Chemistry students sometimes ask if the difference between “3-chloro-” and its isomers is worth the extra paperwork. Over time, the lessons become clear. Reproducibility remains the lifeblood of meaningful research, and even small, seemingly bureaucratic choices regarding starting materials can save months of follow-up work. In my experience, sticking with a product with a solid documentation trail from a reputable source offers huge dividends during peer review or regulatory inspections.

    Handling safety concerns also sits near the top of most researchers’ minds. Familiarity with standard personal protective gear and adherence to established handling guidelines keeps risks low. Like many organic amines, proper ventilation and respectful storage in chemical-resistant containers pay off in both safety and product longevity. Peer-reviewed risk assessments, when available, help demystify potential hazards and ensure teams work with clear expectations rather than vague worry.

    What Sets 4-pyridinemethanamine, 3-chloro- Apart?

    Some products distinguish themselves through utility, others through reliability. Over many years working in both academic and industrial environments, I’ve found 4-pyridinemethanamine, 3-chloro- stands out by managing to offer both. The chlorine substitution gives chemists a way to guide selectivity or tune downstream reactivity without adding complexity to daily handling. This balance earns the compound a regular place in synthetic programs looking to build complexity atop a predictable framework.

    Compared to close relatives, its ability to form strong, directionally predictable bonds offers options not always accessible otherwise. The extra step in synthesis that the 3-chloro group can introduce pays off in more robust intermediates or final products. From an economic perspective, even modest improvements in yield or selectivity help cash-strapped projects to keep moving forward, which feels especially important for small teams or those operating in resource-constrained labs.

    Building Skills and Knowledge with Reliable Foundations

    Learning chemistry goes beyond memorizing reaction schemes. Success depends on paying attention to the materials in play. My time teaching suggests that even undergraduate researchers see a tangible improvement in their results once they recognize the value of high-purity, well-characterized intermediates. Working with a consistent version of 4-pyridinemethanamine, 3-chloro- models good scientific practice, giving newcomers a strong foundation for their studies.

    Mentors commonly encourage students to keep thorough records of starting material batch numbers, supplier quality statements, and details of appearance and handling. These habits, built around trustworthy substances, translate into better skills and sharper troubleshooting down the line. Several student papers from my former lab credited faithful adherence to these principles when their experimental results held up under scrutiny.

    Navigating Regulatory and Ethical Considerations

    With regulatory frameworks tightening and research facing ever-closer review, the days of “anything goes” chemistry seem firmly in the past. Intermediates like 4-pyridinemethanamine, 3-chloro- should come with proper documentation—not only for traceability, but also for ethical clarity. Scientists working near the boundaries of new application spaces have to confirm the route from supplier to flask follows local and national guidelines.

    Transparency, especially for compounds destined for pharmaceutical or agricultural development, stands as a shared responsibility. I’ve watched teams grind to a halt, sometimes for weeks, because one batch lacked the right set of compliance paperwork. It’s not a glamorous part of the work, but methodical, documented sourcing supports faster regulatory approval and smooth downstream progress.

    Environmental Impact and Sustainability

    Modern research can’t ignore environmental responsibility. The best compounds not only perform in the lab but also respect the needs of the world around us. From conversations with colleagues in manufacturing and process development, green chemistry principles guide more decisions each year. For those focused on sustainable synthesis, choosing products with clear information on byproduct formation, storage stability, and risk of volatilization matters.

    Several years back, we ran a project where waste minimization became the deciding factor for route selection. During that process, 4-pyridinemethanamine, 3-chloro- showed favorable profile due to manageable waste streams and the absence of problematic solvents in common preparations. Suppliers who share data about their upstream processes—yields, energy use, water management—help the research community scale innovative chemistries without adding environmental headaches.

    Looking Forward: Opportunities and Needs

    Rapid progress in synthetic chemistry and allied sciences depends on robust, novel intermediates with proven value. The ongoing demand for specialty building blocks pushes suppliers to ensure reproducible supply and encourage transparent dialogue with research end-users. If the last decade is any indicator, compounds like 4-pyridinemethanamine, 3-chloro- play larger roles as new applications emerge. Its presence in pathways toward medicinal agents, advanced materials, or customized agrochemicals looks likely to grow.

    Almost every week, research journals report on innovations sparked by tweaks to molecule structure that until recently seemed inconsequential. Every synthetic chemist knows the feeling of seeing an overlooked intermediate become the key to a breakthrough. In that context, 4-pyridinemethanamine, 3-chloro- offers a reminder that progress rarely comes from grand gestures, but from small, thoughtful decisions about the materials we choose and the problems we solve together.

    Potential Solutions to Research Challenges

    Whenever a research problem turns out stubborn, the cause often traces back to material issues: inconsistent supplies, changes in reactivity due to impurities, or unclear safety information. Addressing these concerns requires more than just higher budgets. Purchasing staff, lab managers, and team leads can reinforce success by establishing clear channels for supplier communication, requesting full certificates of analysis, and cross-referencing existing data with community-shared results.

    Building stronger relationships with trusted providers, scheduling periodic reviews of material quality, and incorporating risk assessments into daily routines all help safeguard project continuity. Several institutions encourage periodic sharing of supplier feedback—good and bad—so that the broader scientific ecosystem benefits from collective experience. Open communication, a willingness to look beyond short-term savings, and shared commitment to safety and sustainability mark the best ways forward.

    Summary

    4-pyridinemethanamine, 3-chloro- hardly ever steals the spotlight, but its importance ripples through countless research programs. Solid handling, structural utility, and dependable sourcing keep it high on the list of useful lab companions. For every project that depends on building from a stable, responsive starting point, it remains a strong pick—one that smart teams return to again and again in shaping the chemistry of tomorrow.