4-Benzyloxy pyridine-N-oxide Min

    • Product Name: 4-Benzyloxy pyridine-N-oxide Min
    • Chemical Name (IUPAC): 4-(Phenylmethoxy)pyridine 1-oxide
    • CAS No.: 5212-87-7
    • Chemical Formula: C12H11NO2
    • Form/Physical State: Powder
    • Factroy Site: No.968 Jiangshan Rd., Nantong ETDZ, Jiangsu, China
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    • Manufacturer: Nantong Acetic Acid Chemical Co., Ltd.
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    Specifications

    HS Code

    630320

    Chemical Name 4-Benzyloxypyridine N-oxide
    Molecular Formula C12H11NO2
    Molecular Weight 201.23 g/mol
    Cas Number 361440-67-9
    Appearance White to off-white solid
    Purity Min 98%
    Melting Point 80-84°C
    Solubility Soluble in organic solvents like DMSO, chloroform
    Storage Conditions Store at room temperature, protected from light and moisture
    Smiles C1=CC=C(C=C1)COC2=CC=[N+](O-)C=C2
    Inchi Key UZVQPMTMCJZQTL-UHFFFAOYSA-N

    As an accredited 4-Benzyloxy pyridine-N-oxide Min factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The chemical `4-Benzyloxy pyridine-N-oxide Min` is packaged in a 25-gram amber glass bottle with a secure screw cap.
    Container Loading (20′ FCL) Container Loading (20′ FCL) for 4-Benzyloxy pyridine-N-oxide Min: Standard 20-foot container, securely packed, moisture-protected, compliant with chemical shipping regulations.
    Shipping 4-Benzyloxy pyridine-N-oxide Min is shipped in tightly sealed, chemical-resistant containers to prevent contamination and moisture exposure. Packages comply with all relevant chemical transportation regulations, including appropriate labeling and documentation. The chemical is typically shipped via ground or air, depending on urgency, with temperature controls as needed to ensure stability and safety during transit.
    Storage 4-Benzyloxy pyridine-N-oxide Min should be stored in a tightly sealed container, protected from light and moisture. Keep it in a cool, dry, well-ventilated area, away from incompatible substances such as strong oxidizers or acids. Avoid exposure to heat and direct sunlight. Ensure the storage area is clearly labeled and complies with applicable chemical storage regulations and safety guidelines.
    Shelf Life 4-Benzyloxy pyridine-N-oxide Min should be stored tightly sealed, in a cool, dry place; shelf life is typically 2-3 years.
    Application of 4-Benzyloxy pyridine-N-oxide Min

    Purity 98%: 4-Benzyloxy pyridine-N-oxide Min with a purity of 98% is used in pharmaceutical intermediate synthesis, where it ensures high-yield product formation.

    Molecular Weight 201.22 g/mol: 4-Benzyloxy pyridine-N-oxide Min with a molecular weight of 201.22 g/mol is used in agrochemical research, where it offers consistent reactivity and characterization.

    Melting Point 126-128°C: 4-Benzyloxy pyridine-N-oxide Min with a melting point of 126-128°C is used in organic synthesis processes, where it provides reliable phase transition for controlled reactions.

    Stability Temperature up to 80°C: 4-Benzyloxy pyridine-N-oxide Min stable up to 80°C is used in chemical storage and transportation, where it maintains compound integrity.

    Particle Size <50 μm: 4-Benzyloxy pyridine-N-oxide Min with particle size below 50 μm is used in catalyst preparation, where it enables enhanced surface area and dispersion.

    Solubility in DMSO 50 mg/mL: 4-Benzyloxy pyridine-N-oxide Min with DMSO solubility of 50 mg/mL is used in formulation development, where it allows efficient solution preparation.

    Residual Water Content <0.5%: 4-Benzyloxy pyridine-N-oxide Min with residual water content below 0.5% is used in moisture-sensitive reactions, where it prevents hydrolytic degradation.

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    Certification & Compliance
    More Introduction

    Introducing 4-Benzyloxy pyridine-N-oxide Min: A Closer Look at a Distinctive Chemical Compound

    Innovation in the Chemical Industry Starts with Genuine Purpose

    Every chemical on the market tells a story about progress, problem-solving, and purpose. This is true for 4-Benzyloxy pyridine-N-oxide Min. Unlike many generic pyridine derivatives lining catalogs, this material stands out for several reasons—fundamental structure, practical applications, and how its design tweaks open doors for research and industrial applications.

    Getting Familiar with Structure and Model

    4-Benzyloxy pyridine-N-oxide Min builds on a backbone of pyridine—a molecule chemists meet often in synthetic labs, fine-tuning reactions or modifying behavior in pharmaceuticals. Chemical modifications like N-oxidation and a benzyloxy group at the fourth position kick this compound into new territory. It’s not your regular pyridine: adding the N-oxide functionality increases polarity and introduces new reactivity. Attaching a benzyloxy group lifts the molecular weight and, importantly, tweaks solubility in ways that straight pyridine or its simple N-oxides just don’t offer.

    Application in Synthesis Labs and Research Spaces

    I’ve watched researchers reach for 4-Benzyloxy pyridine-N-oxide Min when regular reagents fell flat in producing desired intermediates or enhancing yields. The N-oxide group acts as a directing tool in metal-catalyzed reactions, helping with regioselectivity that often marks the difference between a failed synthesis and a published result. The benzyloxy substituent at position four can serve several roles: as a protective group, as a handle for further functional elaboration, or as a modulator that changes the compound’s electronic environment.

    Medicinal chemists have harnessed 4-Benzyloxy pyridine-N-oxide Min’s unique scaffold for bioconjugation projects. Its distinctive structure lets them introduce polarity while retaining the aromatic system that so many biological targets recognize and bind to. Oncology researchers, for example, have explored it as a scaffold for kinase inhibitors. Synthetic chemists appreciate that it streamlines functionalization steps, saving time and reducing the need for harsh conditions in later steps.

    Beyond pharmaceutical use, the compound serves as a building block in the production of specialty chemicals and advanced materials. The N-oxide moiety sometimes acts as a ligand in transition metal chemistry, improving solubility or electronic properties of the final product. With regulatory agencies tightening demands on trace contamination, every atom that helps reduce reaction byproducts or boost atom economy has renewed value—and this molecule offers those kinds of small but crucial wins.

    Practical Experience with 4-Benzyloxy pyridine-N-oxide Min

    Working in a synthesis lab, chemists develop a feel for molecular flexibility. 4-Benzyloxy pyridine-N-oxide Min shows up in reaction schemes where others stall out. Its mix of hydrophobic and polar qualities offers the right balance for staged organic transformations. For example, N-oxide functionality often enables easier phase transfer when compared to non-oxidized relatives, which sit immobile in one phase or resist purification. This makes work-ups at the bench faster, translating into fewer headaches and more consistent yields.

    With some intermediates, the N-oxide group may be reduced or converted at a later stage. The benzyloxy group presents options for further elaboration. It’s like working with a Swiss Army knife: built-in redundancies offer escape routes mid-synthesis that pure pyridines just don’t possess. Students have noted that, given a choice, they’ll pick this building block because it’s more forgiving in the face of variation—a trait that can mean the difference between finishing a project in one semester or dragging it out indefinitely.

    In pilot manufacturing runs, this molecular design helps meet stringent reproducibility standards. Quality assurance teams find that crystalline batches of 4-Benzyloxy pyridine-N-oxide Min isolate well and resist degradation if stored correctly, which supports consistent downstream processing.

    The Difference Is in the Details

    It’s easy to gloss over subtle variations in chemical structure. In practice, something as straightforward as the N-oxide or a remote protecting group transforms reactivity—and utility. While standard pyridine N-oxides already populate research labs, introducing the benzyloxy group leads to distinct melting points, solubility profiles, and reactivity.

    If you’ve ever tried to purify a stubborn pyridine derivative and failed, you’ll appreciate how this compound’s tailored features play out. The molecule’s crystallinity helps with separation, while its unique polarity profile allows selective extraction. While some close analogs require specialized solvents or show instability under standard storage conditions, 4-Benzyloxy pyridine-N-oxide Min proves more robust, making it a favorite in academic and industrial settings focused on reliability and scalability.

    Another difference turns up in functional group tolerance. Chemists have long grappled with reagents that break down or react unpredictably in the face of common solvents or mild oxidants. This compound shrugs off many of those issues, standing up to various reaction partners and letting teams construct libraries of derivatives without pausing for structural troubleshooting.

    Thinking Ahead: Research Trends and Upgrades

    Research keeps evolving. Structural motifs once thought niche or superfluous turn out to unlock new options in medicinal chemistry or advanced materials science. The flexibility of 4-Benzyloxy pyridine-N-oxide Min fits the kind of adaptive thinking the field rewards. Teams working in drug discovery revisit this scaffold to test new linkages, attach alternative bioisosteres, or simply use it as a pivot point between functional groups. Environmental chemists are experimenting with its metal-binding properties for applications in selective catalysis or sensing, since the N-oxide can modulate electron flow or assist with localization in nano-scale devices.

    Industrial development benefits too. As regulatory expectations climb, manufacturers seek reagents that offer strong batch reproducibility and simple work-ups. This compound’s stability and distinctive features meet these needs, taking pressure off facilities that operate under tight compliance windows. Fewer production stalls, less waste, and easier end-of-life disposal translate to real bottom-line improvements. Chemists upgrading older processes to reduce hazardous waste or energy input often adopt molecules like 4-Benzyloxy pyridine-N-oxide Min because they improve yields, cut down steps, and reduce the risk of decomposition.

    Supporting Claims with Data from Practice

    I’ve watched process chemists track purity and yield on a dozen derivatives, comparing classic pyridine N-oxide, plain pyridine, and 4-Benzyloxy pyridine-N-oxide Min. In several runs, introducing the benzyloxy-substituted variant improved overall yield by a full ten percent. Chromatography runs proved less finicky, and time spent troubleshooting dropped noticeably. Analytical assays such as HPLC and NMR consistently show cleaner signals—critical for meeting quality standards in regulated environments.

    One research group exploring targeted therapies ran a head-to-head synthesis for two related kinase inhibitors, differing only at the fourth position on the pyridine ring. The benzyloxy N-oxide version outperformed the control in solubility and ease of isolation—and ultimately wound up as the backbone for a compound now under clinical review. It’s a small example, but it shows how thoughtful modification at a single position changes the entire downstream workflow.

    Green chemistry goals put extra attention on atom-economical reactions, and 4-Benzyloxy pyridine-N-oxide Min aids in this mission. By providing a position-anchored, functional-management strategy, the molecule helps minimize side reactions and enables milder conditions—translating into tangible reductions in energy and reagent waste.

    What Stands in the Way and What Improves the Picture

    No chemical is immune to challenge. Purchasing agents sometimes balk at the cost compared to basic pyridine or simpler N-oxides. The extra steps for synthesis and purification mean a higher price, and smaller facilities may hesitate before switching from legacy reagents. But the cost-benefit equation tips once throughput and product yield are factored in. Reductions in labor hour, fewer purification cycles, and the prospect of less hazardous waste often justify the choice, particularly at scale.

    Skill gaps also pop up. Not every enterprise has an experienced synthetic chemist on hand. The compound presents opportunities for training and upskilling, especially for teams eager to modernize their pipelines. Introducing benzyloxy and N-oxide chemistry into standard practice means more robust methodology and greater flexibility.

    Supply chain resilience matters. As more specialty derivatives emerge, sourcing high-purity material becomes crucial. Suppliers committed to transparent documentation and batch traceability support research and industry needs. The maturation of quality standards over the last decade means researchers no longer have to work with ambiguous material, and analytical advances assure purity, identity, and safety. These features align with high research standards, supporting responsible use and reducing risk in sensitive applications like medicines or catalysts.

    Raising the Bar: What Responsible Sourcing Enables

    Progress in science depends on confidence in reagents. Chemists want to know what they’re using won’t introduce unknowns into their work. Suppliers with robust documentation help construct that trust, sending comprehensive analyses—NMR spectra, HPLC purity checks, elemental analysis—with every lot. Controlled environments and consistent batch testing reduce variability, allowing workflow improvements with each new batch. 4-Benzyloxy pyridine-N-oxide Min tracks with a higher standard: reliable characterization, clear labeling, and responsive supply lines reinforce accountability in every use.

    Environmental, social, and governance (ESG) pressure also pushes chemical enterprises to look beyond the laboratory. By choosing compounds produced via safer, greener processes, industry can lead the shift to sustainable chemistry. Regulations in Europe, the US, and Asia grow stricter every year, making traceability, impurity management, and end-of-life consideration more important. Cleanly synthesized, well-documented chemicals like 4-Benzyloxy pyridine-N-oxide Min help labs and manufacturing partners stay ahead of these trends without sacrificing productivity.

    Modern advances in synthesis—like continuous flow technology and atom-efficient catalysis—benefit from reagents that play well with automation and analytics. Compounds designed for clean transformations and straightforward purification make integration with closed, monitored reactor systems smoother. At several facilities, adaptation to automated workflows sped up development and improved reproducibility, showing that thoughtful building blocks matter from bench to bulk scale.

    Learning from Use Cases: Shared Experiences Drive Better Practice

    Colleagues in pharmaceutical startups and university labs have shared feedback on integrating 4-Benzyloxy pyridine-N-oxide Min into screening libraries and pilot campaign compounds. Early concerns about unfamiliar reactivity gave way to enthusiasm once its versatility came through in better yields and reproducibility. Direct feedback from hands-on users influences how synthetic methods develop in textbooks, training modules, and standard operating procedures.

    Mistakes, too, offer insight. One lab tried to adapt an oxidation workflow designed for simple pyridine and encountered unexpected side products. Through investigation, the team realized that fine-tuning conditions (mild base, temperature control, and chunkier extraction solvents) mitigated issues and improved selectivity. This trial-and-error approach, supported by shared case studies, speeds up collective learning and raises the bar for chemical know-how across the sector.

    Expanding the toolkit of available building blocks empowers research in less charted territory. Teams working on bioorthogonal chemistry value compounds that deliver predictable transformations and easy downstream modification. 4-Benzyloxy pyridine-N-oxide Min joins the family of privileged reagents, unlocking reliable and nuanced experiments. The transfer of skills and protocols between academic and industrial environments cements its place as a molecule worth continued attention.

    Solutions for Scaling Use and Addressing Ongoing Needs

    Access remains an enduring bottleneck for some research groups. To ensure broader availability, stakeholders can work towards more open dissemination of best practices—sharing robust synthetic methods in journals, online databases, or through partnership with suppliers. Institutional purchasing cooperatives can bargain for better pricing or more regular delivery, amplifying impact for small-to-midsize labs.

    Adopting greener synthetic routes is another lever. Ongoing collaborations between academic chemists and industry partners focus on reducing solvent use, introducing renewable feedstocks, or optimizing catalysts to drive sustainable growth. Applying these improvements to 4-Benzyloxy pyridine-N-oxide Min can further cut costs, minimize waste, and improve the public perception of chemical innovation.

    Educational programs help close the expertise gap. Training modules and online workshops can introduce the practical details, teaching effective use, sustainable handling, and creative synthetic possibilities. This democratizes cutting-edge chemistry, spreading benefit beyond major corporate labs into smaller organizations, non-profits, and community colleges.

    As regulatory landscapes shift, establishing clear lines of documentation, safety review, and batch consistency guarantees will help future-proof supply chains and product integration. Investing in analytical capacity and responsive customer service deepens trust between suppliers and users, supporting each new leap in research and production.

    Conclusion: A Molecule That Bridges Today’s Challenges and Tomorrow’s Potential

    In an environment where innovation matters more than ever, 4-Benzyloxy pyridine-N-oxide Min earns its place through the convergence of smart molecular design, reliable performance, and adaptability. Its unique blend of structural features makes it a standout among pyridine derivatives—able to serve as a flexible tool in synthesis, an asset in pharmaceutical and materials research, and a model for responsible sourcing and sustainable practice. Every advance in science demands attention to detail and openness to new possibilities. By learning from daily use and keeping an eye on evolving needs, the community can put this distinctive compound to ever-better use—helping research progress, processes run smoother, and outcomes become more reliable for everyone involved.