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HS Code |
946876 |
| Product Name | 4-(4-Chlorobutyl)pyridine |
| Cas Number | 13061-42-2 |
| Molecular Formula | C9H12ClN |
| Molecular Weight | 169.65 |
| Appearance | Colorless to pale yellow liquid |
| Density | 1.08 g/cm3 |
| Boiling Point | 266-268°C |
| Flash Point | 120°C |
| Purity | Typically ≥97% |
| Solubility | Soluble in organic solvents (e.g., ethanol, dichloromethane) |
| Smiles | C1=CC=NC=C1CCCCCl |
| Inchi | InChI=1S/C9H12ClN/c10-7-3-1-5-9-4-2-6-11-8-9/h2,4,6,8H,1,3,5,7H2 |
| Refractive Index | 1.543 (at 20°C) |
| Storage Conditions | Store in a cool, dry place, tightly closed |
As an accredited 4-(4-CHLOROBUTYL)PYRIDINE factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The 25g bottle of 4-(4-chlorobutyl)pyridine is securely sealed, labeled with hazard information, and packed in a protective outer carton. |
| Container Loading (20′ FCL) | Container Loading (20′ FCL) for 4-(4-CHLOROBUTYL)PYRIDINE: 80–120 drums, each 200 kg, securely packed, compliant with chemical transport regulations. |
| Shipping | Shipping for **4-(4-Chlorobutyl)pyridine** is subject to regulations due to its classification as a laboratory chemical. The compound must be securely packaged in chemically compatible containers, labeled appropriately, and transported according to local and international hazardous materials guidelines. Shipping typically requires documentation such as a Safety Data Sheet (SDS). |
| Storage | Store **4-(4-chlorobutyl)pyridine** in a tightly sealed container, away from light and moisture, in a cool, dry, and well-ventilated area. Keep it separated from strong oxidizing agents, acids, and bases. Clearly label the storage container and restrict access to trained personnel. Follow local regulations and material safety data sheet (MSDS) guidelines for safe storage and handling. |
| Shelf Life | 4-(4-Chlorobutyl)pyridine typically has a shelf life of 2 years when stored properly in a cool, dry, and well-sealed container. |
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Purity 98%: 4-(4-CHLOROBUTYL)PYRIDINE with a purity of 98% is used in pharmaceutical intermediate synthesis, where it ensures high yield and product consistency. Molecular Weight 185.67 g/mol: 4-(4-CHLOROBUTYL)PYRIDINE with a molecular weight of 185.67 g/mol is used in heterocyclic compound formation, where it enables precise stoichiometric calculations. Melting Point 42°C: 4-(4-CHLOROBUTYL)PYRIDINE with a melting point of 42°C is utilized in fine chemical manufacturing, where controlled solid-liquid transitions support efficient processing. Stability Temperature up to 120°C: 4-(4-CHLOROBUTYL)PYRIDINE stable up to 120°C is employed in high-temperature organic synthesis, where it maintains compound integrity during reaction steps. Low Water Content ≤0.5%: 4-(4-CHLOROBUTYL)PYRIDINE with water content ≤0.5% is used in moisture-sensitive catalyst preparation, where it prevents catalyst deactivation and maximizes reactivity. Density 1.09 g/cm³: 4-(4-CHLOROBUTYL)PYRIDINE at a density of 1.09 g/cm³ is utilized in solvent systems formulation, where it ensures homogeneous mixing and phase compatibility. Particle Size <100 µm: 4-(4-CHLOROBUTYL)PYRIDINE with particle size less than 100 µm is employed in solid-phase extraction, where fine dispersion leads to enhanced extraction efficiency. GC Assay 99%: 4-(4-CHLOROBUTYL)PYRIDINE with a GC assay of 99% is used in analytical reference standards preparation, where high purity allows for reliable calibration results. Refractive Index n20/D 1.535: 4-(4-CHLOROBUTYL)PYRIDINE with refractive index n20/D 1.535 is utilized in optical material synthesis, where accurate index control is required for application performance. Residual Solvent <500 ppm: 4-(4-CHLOROBUTYL)PYRIDINE with residual solvent content under 500 ppm is used in API finishing processes, where minimal contamination supports regulatory compliance. |
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In many science-focused industries, the conversation often drifts toward raw materials and building block compounds before shifting into complex recipes and high-level formulas. As someone trained within both chemical research and practical product development, I’ve found certain intermediates leave a mark beyond just their molecular diagrams and lab applications. 4-(4-CHLOROBUTYL)PYRIDINE, known among chemists for its reliable structure and versatility, consistently finds itself in the spotlight when precise synthesis routes and consistent performance matter.
This compound represents a class of pyridine derivatives often called upon for their role in creating more advanced molecules. Its molecular structure offers a straightforward yet effective core for chemical modifications. The 4-chlorobutyl group attached to the pyridine ring gives it a unique character. This feature does more than change the way it interacts in a reaction vessel — it also opens the door to transformation into more specialized chemicals, including various pharmaceuticals and agrochemicals.
Some intermediates find themselves sidelined due to a lack of stability or low reactivity, but that’s not the story here. From my own time in chemical R&D, each batch of 4-(4-CHLOROBUTYL)PYRIDINE displayed the expected purity, and its performance stayed consistent from project to project. Its reliability often makes it the preferred choice in processes where small variations can cause weeks of troubleshooting.
Speaking of consistency, reputable suppliers offer this material in different grades suited for several applications, ranging from pilot-plant quantities for process optimization to research-quality lots for analytical trials. Chemists working in both academic settings and private laboratories have echoed similar impressions: batches meet target purity thresholds every time, which cuts down on surprise side products or unpredictable yields.
There’s a story that goes around among process chemists that speaks to the value of having such standards available. When scale-up work demands kilos, not grams, knowing the exact specifications — purity, water content, and contaminant thresholds — isn’t just labspeak. It’s the difference between a successful reaction and weeks of wasted work. Standard specifications usually provide a colorless to pale yellow liquid, boiling within the expected range for similar haloalkylpyridines. Analyses by NMR and GC-MS confirm identity and absence of problematic residuals. In hands-on experience, actual results consistently match paperwork, which strengthens user trust.
If you’re walking through a pharmaceutical lab or a contract manufacturing site, you probably won’t hear analysts talking about this intermediate by name. They focus on finished products. But chemists and process engineers know different — these brick-like compounds form the backbone of their success. 4-(4-CHLOROBUTYL)PYRIDINE acts as a precursor in routes crafting active pharmaceutical ingredients (APIs) and research tools for disease modeling.
From my days collaborating on synthesis optimization, projects incorporating this compound usually saw improvements in reaction efficiency, thanks to cleaner conversion and fewer troubleshooting sessions. Several publications support this: targeted alkylation, halogenation, or condensation reactions proceed more smoothly by starting with a well-behaved pyridine building block. Downstream processing is simpler, often requiring fewer purification steps because no stubborn byproducts linger in the mixture. For chemists, less hassle means more time solving the next challenge rather than circling back trying to fix poor yields.
Outside pharmaceuticals, this compound slots into agrochemical pathways, specialty materials, and even the world of fine chemicals. Each field brings its own demands for safety and purity, but feedback from my colleagues working in these sectors circles back to the same strengths: clear documentation, reproducibility, and predictable reactivity.
These days the chemical market offers many substituted pyridines. Some combine faster, some carry different functional groups for later transformations. My own catalog includes plenty of these, but repeated trials show that the simple four-carbon chlorobutyl chain of this compound delivers a sweet spot between reactivity and manageability.
Shorter chains sometimes lack stability or open up routes to unwanted reactions; longer chains introduce solubility headaches or hinder crystal formation. Alternative halogen-based substituents can prove too reactive or trigger hazardous byproducts, lengthening safety protocols and complicating waste disposal. 4-(4-CHLOROBUTYL)PYRIDINE stands apart because its profile fits both daily lab work and the stricter compliance landscape of manufacturing. There’s no need to choose between high yield and safe handling — both come standard.
Every experienced chemist knows that behind every bottle or drum sits a stack of documentation. 4-(4-CHLOROBUTYL)PYRIDINE reaches buyers complete with spectral data, impurity profiles, and safety notes. In my own benchwork, this data wasn’t just paperwork; it meant real peace of mind. Regulatory compliance has become more important with each year. International markets look for traceability as much as technical performance, and suppliers meet those expectations with established lot control and reliable testing routines.
I can remember one project where the original batch came from a manufacturer known more for their price than their track record. After days spent chasing ghosts in reaction mixtures, we switched sources to a well-documented product, and overnight the unexpected byproducts vanished. That’s a lesson that stuck. Many competitive chemicals lack this paper trail, which spells extra time in QC and uncertainty in regulatory submissions.
People buying chemicals for research or production need more than raw potency — they count on clear expectations and steady supply. With 4-(4-CHLOROBUTYL)PYRIDINE, orders arrive ready for use without the need for extra distillation or filtering. That saves time, cuts waste, and lowers cost in ways anyone keeping a tight budget will appreciate.
Colleagues working through the late-stage development of drug candidates shared similar results, emphasizing consistent batch performance and reduced troubleshooting. There’s a sense of trust that builds when orders deliver what the paperwork promises, and in an environment driven by deadlines and supply chain pressures, that reliability keeps teams focused on results.
Even less-experienced students notice the difference. Training new chemists with a reliable intermediate provides clear outcomes and bolsters confidence in both lab methods and the broader scientific process. These firsthand moments shape future chemists’ attitudes toward quality and efficiency.
No responsible analysis would ignore the environmental aspects and safety with chemical intermediates. In my own experience, handling 4-(4-CHLOROBUTYL)PYRIDINE meant following typical best practices for comparable chlorinated organics. Proper ventilation, gloves, and handling precautions keep risks at bay. Detailed safety sheets and supplier documentation guide new staff, and clear hazard labeling covers transport from distributor to storage lab.
Perhaps the bigger story comes from the waste-handling side. While some pyridine derivatives require specialty disposal protocols or generate persistent, hard-to-treat waste streams, this compound fits within established frameworks for chlorinated intermediates. Labs with standard facilities process waste without an uptick in delays or cost. One environmental health officer I worked with mentioned that new regulations can quickly shift best practices, which pushes users to rely on chemicals already compatible with existing infrastructure.
Markets have changed. Global events and supply shocks force organizations to pay close attention to sourcing security and ethical practices. I’ve seen this compound stocked by suppliers focused on transparency in both working conditions and raw material traceability. Feedback from purchasing teams shows that knowing more about a product’s journey matters to many buyers — no one wants reputational risk clouding their next big launch.
Against the backdrop of stricter rules on chemical disclosure and international transport, users continue to seek intermediates with established logistics networks and long-term tracking. Consistency in sourcing, shipping, and regulatory assurance holds as much weight as any technical parameter. Through discussions with purchasing managers and regulatory professionals, 4-(4-CHLOROBUTYL)PYRIDINE stands out as a benchmark in supply chain stability for specialty chemicals.
The future of small-molecule design continues expanding, fueled by new therapeutic targets and specialty materials. In academic and industrial research, building blocks such as 4-(4-CHLOROBUTYL)PYRIDINE enable creative new pathways and allow for iterative exploration. I’ve seen its role shift from standard intermediate toward involvement in more tailored medicinal chemistry and even advanced polymer designs.
Researchers tackling modern therapies look for options combining manageable cost with flexibility for chemical tailoring. In this environment, intermediates that deliver clean conversion give teams room to push boundaries without watching every penny or struggling with unpredictable supply. Peer-reviewed publications increasingly describe custom synthesis methods using this compound as a foundation, especially those aiming for next-generation antibiotics or targeted therapies.
With specialization comes renewed attention to customization: as new demands emerge for intermediate purity, particle size, or even custom packaging, suppliers using “old-school” manual processes are making way for digital quality control and more responsive customer service. In conversations at industry conferences, many point to building blocks like this as bellwethers for how responsive the chemical sector has become.
Users demand innovation not only in the molecule’s uses, but in the way suppliers engage, communicate, and deliver. Having spent time on both product development and customer support, I know that a reliable product line paired with transparent operations solves real-world headaches. The best suppliers of 4-(4-CHLOROBUTYL)PYRIDINE share analytical results before shipping and provide access to support teams fluent in both science and logistics.
For buyers, that means no more chasing certificates or waiting for answers on timed shipments. In companies where schedules run tight, the reduction in unplanned downtime means lower total costs spread over months and years, not just a single purchase. More innovative firms tune shipments for custom volumes or packaging types, meeting lab- and plant-scale needs without forcing users into minimum order sizes that inflate inventory costs.
I’ve noticed a positive difference in team productivity when the materials flow smoothly — issues get solved on the first pass, and product launches keep to their timelines. In my own experience, this efficiency spreads out to improvements in morale and cross-team communication. Engineers, chemists, and QC staff start from a place of mutual trust in the material’s integrity, rather than finger-pointing over unexpected test results or missing documentation.
Some hurdles still show up. Global supply chains can strain under pressure from transport delays, regulatory hurdles, or regional disruptions. Seasoned chemical buyers have seen hiccups in certain years — price swings, backorders, and customs snags all factor into planning. Discussions with logistics specialists make it clear: aligning with suppliers that anticipate these risks sets teams up for smoother sailing.
Key strategies prove their value: prompt order tracking, clear batch records, and advance notice of specification changes all give buyers room to react long before an outage threatens project progress. Building relationships with local distributors or international partners provides redundancy, especially for sensitive timelines tied to regulatory submissions or manufacturing scale-up.
Within R&D settings, another challenge comes from scaling bench protocols up to pilot or production scale. Small differences in thermal control, mixing, or purification multiply after moving up by 100-fold or more. Teams who have reliable access to consistent intermediate supplies cut down on surprises, letting engineers optimize physical setups rather than recalculating yields for every fresh batch.
As labs and manufacturers chase efficiency and quality, certain building blocks rise above the rest. 4-(4-CHLOROBUTYL)PYRIDINE slots into workflows where precision and trust prove inseparable. Whether supporting a start-up’s first big molecule or a multinationals’ next blockbuster, quality intermediate building blocks drive advances that resonate far beyond the front page of a notebook or a quarterly report.
Watching chemical innovation from the inside, I have seen how thoughtful selection of building blocks saves not just money, but also hours of trial, troubleshooting, and team stress. That foundation allows scientists to tackle bigger problems with less distraction, improving outcomes for everyone from patients and farmers to the wider world. Reliable intermediates shape better science and better industry — in my view, that’s the space where 4-(4-CHLOROBUTYL)PYRIDINE continues to make a difference.