3-pyridinemethanol, 5-amino-

    • Product Name: 3-pyridinemethanol, 5-amino-
    • Chemical Name (IUPAC): (5-aminopyridin-3-yl)methanol
    • CAS No.: 22280-12-0
    • Chemical Formula: C6H8N2O
    • Form/Physical State: Solid
    • Factroy Site: No.968 Jiangshan Rd., Nantong ETDZ, Jiangsu, China
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    • Manufacturer: Nantong Acetic Acid Chemical Co., Ltd.
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    Specifications

    HS Code

    828082

    Iupac Name 5-aminopyridin-3-ylmethanol
    Molecular Formula C6H8N2O
    Molecular Weight 124.14 g/mol
    Cas Number 20868-96-6
    Pubchem Cid 2818092
    Appearance Solid (powder or crystals)
    Melting Point 126-131°C
    Boiling Point 314.1°C at 760 mmHg
    Solubility In Water Moderately soluble
    Smiles C1=CC(=CN=C1CN)N
    Inchi InChI=1S/C6H8N2O/c7-6-2-5(3-9)1-4-8-6/h1-2,4,9H,3,7H2
    Pka Approx. 5.5 (amine protonation)
    Density 1.19 g/cm3
    Flash Point 143.9°C
    Refractive Index 1.620

    As an accredited 3-pyridinemethanol, 5-amino- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging for 3-pyridinemethanol, 5-amino- (25 grams) is a sealed amber glass bottle with a tamper-evident cap.
    Container Loading (20′ FCL) Container Loading (20′ FCL) for 3-pyridinemethanol, 5-amino-: Securely packed in drums or bags, maximizing space for safe, compliant shipment.
    Shipping 3-Pyridinemethanol, 5-amino- should be shipped in compliance with chemical safety regulations. It must be securely packaged in sealed containers, protected from moisture and light, and labeled according to hazard classifications. Transport should follow relevant local, national, and international guidelines, including appropriate documentation and safety data sheets to ensure safe delivery.
    Storage Store 3-pyridinemethanol, 5-amino- in a tightly sealed container, away from light, moisture, and incompatible substances such as strong oxidizers. Keep the container in a cool, dry, well-ventilated area, ideally at room temperature. Ensure proper labeling and avoid exposure to heat or open flames. Use appropriate personal protective equipment when handling and follow institutional safety protocols.
    Shelf Life 3-pyridinemethanol, 5-amino- should be stored cool and dry; typical shelf life is 2 years in unopened, properly stored containers.
    Application of 3-pyridinemethanol, 5-amino-

    Purity 98%: 3-pyridinemethanol, 5-amino- with a purity of 98% is used in pharmaceutical intermediate synthesis, where it ensures high yield and minimal byproduct formation.

    Melting point 125°C: 3-pyridinemethanol, 5-amino- with a melting point of 125°C is used in organic synthesis, where it facilitates efficient recrystallization processes.

    Molecular weight 138.16 g/mol: 3-pyridinemethanol, 5-amino- of molecular weight 138.16 g/mol is used in medicinal chemistry research, where it allows precise stoichiometric calculations.

    Particle size <50 μm: 3-pyridinemethanol, 5-amino- with particle size below 50 micrometers is used in formulated compounds, where it enables rapid dissolution and homogeneous mixing.

    Stability temperature 60°C: 3-pyridinemethanol, 5-amino- stable up to 60°C is used in analytical procedures, where it maintains structural integrity during sample processing.

    Water solubility 15 mg/mL: 3-pyridinemethanol, 5-amino- with water solubility of 15 mg/mL is used in biochemical assay development, where it provides consistent solution preparation.

    Viscosity grade low: 3-pyridinemethanol, 5-amino- with low viscosity grade is used in flow-based reaction systems, where it enhances reagent delivery and mixing efficiency.

    Hydrochloride salt form: 3-pyridinemethanol, 5-amino- in hydrochloride salt form is used in drug formulation studies, where it improves compound stability and ease of handling.

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    Certification & Compliance
    More Introduction

    Understanding 3-pyridinemethanol, 5-amino-: Practical Applications and Real-World Benefits

    Introduction

    Chemistry often seems like a maze, especially when you step into the world of specialized compounds. Take 3-pyridinemethanol, 5-amino- as a good example. For those in pharmaceutical research, chemical development, and lab testing, this compound is more than just an arrangement of atoms. Anyone who has worked with organic synthesis or drug discovery knows the hunt for the right building blocks can make or break a project. Having firsthand experience with research labs ranging from tight-budget startups to university teams, I’ve seen how finding a compound with the right properties speeds up work and avoids technical snags down the road.

    With 3-pyridinemethanol, 5-amino-, you’re dealing with a substance that brings together a distinctive pyridine core and a functional alcohol group. An amine group at the 5-position rounds out its chemical profile—a small tweak on paper, but one that changes how the compound fits into different reactions. Instead of grabbing whatever’s available, researchers look for specific structures like this to avoid roadblocks in their synthesis steps.

    Breaking Down the Model and Specifications

    In the catalog, 3-pyridinemethanol, 5-amino- usually comes in high-purity grades to suit delicate chemical reactions. Many suppliers offer this compound in powders or crystalline solid form, somewhere in the off-white range. Researchers appreciate that they don’t have to spend hours purifying or filtering; the substance tends to arrive ready for synthesis use—something any chemist with a tight deadline will appreciate. As for molecular weight and structure, understanding that the molecule includes a pyridine ring attached to a methanol and an amino group gives clarity on predicting how it will behave in common reactions. Experiences in graduate-level chemistry drives home that synthetic predictability beats improvising with substitutes.

    From a structural standpoint, adding an amino group at the 5-position creates more than just a cosmetic difference. Anyone who has run syntheses involving aromatic amines knows this change can tune the electronic properties in key ways—opening up new avenues for coupling, condensation, and transformation steps. The difference shows up in yields, purity, and product character, which matters if your team depends on consistent outputs or if downstream steps hinge on this reagent doing its job without surprises.

    Real-World Usage: Beyond the Textbook

    Not every molecule fits seamlessly into process chemistry or early-stage research. Some compounds force you to adjust conditions, change solvents, or rethink basic steps—all headaches for labs that value reliable, robust workflow. The first time I encountered 3-pyridinemethanol, 5-amino-, my team was trying to develop ligands for metal complexes. The difference it made in both solubility and reactivity gave us a shortcut, sidestepping a pile of complex workarounds.

    Pharmaceutical teams tend to use this compound as a chemical intermediate, particularly when building up molecular libraries for new drug candidates. The molecule’s basic skeleton makes it easy to append other functional groups or engage in selective modifications. Polishing up a lead drug candidate without side reactions or tricky purification steps depends a lot on the ability to predict each building block’s behavior under different conditions. Because of the alcohol and amine groups, chemists can tether additional units or introduce protective groups without tying themselves in knots.

    Agrochemical projects use this molecule as well. Anyone who has tried designing small molecules to fine-tune biological activity—say, as herbicide or pesticide candidates—knows how adjusting the pyridine ring can dial up or down the compound’s effects. Functional groups at key positions give more leeway for structure-activity exploration without making the synthesis path a headache for scale-up staff later on.

    Even routine lab applications benefit. On the analytical chemistry side, 3-pyridinemethanol, 5-amino- can serve as a standard or calibration target for quality control, letting technicians get reproducible, reliable instrument readings where small chemical differences matter. In my own lab experience, fewer calibration headaches mean more time hitting project milestones and less troubleshooting for overstressed lab assistants.

    The Importance of Transparency and Quality Control

    Any team relying on chemical reagents for research or production needs to know what’s in the bottle. A few years back, a partner lab tried cutting costs by ordering a lower-grade version of a similar compound. The move backfired—unexpected impurities led to byproducts, throwing off data and wasting resources. With 3-pyridinemethanol, 5-amino-, many suppliers provide technical documentation, batch analysis, and purity certificates, which go a long way in minimizing these headaches.

    Quality checks become crucial in pharmaceutical and agricultural projects, since regulators want to see clear, consistent paperwork. Having a transparent source of 3-pyridinemethanol, 5-amino- means smoother audits and easier reporting. Working under pressure from both management and regulatory agencies, I’ve learned the hard way that scrambling to justify questionable reagent quality drags out timelines and introduces extra risk.

    Labs investing in reproducible results value suppliers who explain synthesis pathways, impurity profiles, and storage recommendations. Attention to stable packaging and rigorous transportation standards reduces worries about product degradation—something that can spell the difference between success and stubborn analytical anomalies. Long-term research investments get a shot in the arm from standards like these.

    Differences from Related Compounds: Small Modifications, Big Impacts

    At first glance, 3-pyridinemethanol, 5-amino- looks like it belongs to a crowd of similar molecules. Tweaking the position of the amino group seems minor, but anyone who’s had to optimize a catalytic process knows the difference can be dramatic. Switching between a 2-, 3-, or 5-amino group changes electron distribution on the ring and shifts the molecule’s interaction with catalysts or target sites. This can bump up selectivity in coupling or condensation reactions and change how easy it is to crystallize or purify the end product.

    Comparing 3-pyridinemethanol, 5-amino- with its relatives—such as 2-amino or 4-amino derivatives—shows more than just a change of address for the functional group. The 5-amino version nets a different reactivity profile in common synthetic protocols. Labs pressed for efficient hit validation or new pathway exploration can go directly to the functional core rather than fuss with endless protection or deprotection schemes. A frustrating battle with side-products or uncooperative intermediates reminds any chemist of the danger of using the wrong isomeric form.

    Sometimes the methanol group enables unique solubility and modification options that aren’t possible with other derivatives. In peptide synthesis or ligand attachment, this gives more flexibility while creating fewer lab bottlenecks. Making a mistake by using a 2-pyridinemethanol or a non-amino variant pushes you into all sorts of trouble—poor yields, off-target reactivity, or outright instability. A small change in structure leads to a chain reaction of practical consequences.

    The Human Side of Laboratory Progress

    Chemical research isn’t just about abstract structures and specifications—it’s about saving time, money, and energy. For teams under pressure to deliver new pharmaceuticals or refine industrial processes, the selection of each compound stakes a claim on future success. There’s the story about rushing a multi-step synthesis late at night, only to have an unexpected impurity throw off the entire sequence because the wrong pyridinemethanol derivative showed up in a shipment. That kind of frustration lingers, and it reshapes daily practices—placing quality, transparency, and reliability in front of bottom-line savings.

    With 3-pyridinemethanol, 5-amino-, the odds lean more toward hitting project goals on time. Research teams can stick to proven workflows, reduce the burden of purification, and deal with fewer hidden surprises. That translates into credible results, publishable data, and greater confidence when scaling up from milligram-scale experiments to something large enough for pilot production. Students and professionals alike start to see research as less of a gamble and more of a well-mapped journey.

    Pushing Forward: Meeting New Challenges in Research

    The world of applied chemistry continues to demand new approaches and better results—faster, safer, and with fewer unknowns. Choosing intermediates like 3-pyridinemethanol, 5-amino- reflects the shift toward compounds designed for efficiency and flexibility. As chemical reactions grow more sophisticated, researchers rely on building blocks with predictable, adaptable properties. Whether constructing new active pharmaceutical ingredients or mapping out unexplored reaction space, the right starting materials matter just as much as the latest equipment.

    Chemists in discovery teams face fresh challenges: meeting stricter environmental standards, minimizing waste, and operating within tighter budgets all while pushing past what’s been done before. The capability that comes from using a well-characterized intermediate goes beyond the reaction flask. Down the line, efficiency in creating and screening derivatives means more shots on goal—whether aiming for a first-in-class drug or a novel agrochemical. The impact is concrete.

    Practical Solutions: Sourcing, Handling, and Scaling Up

    Experience has taught that chemical workflow is only as good as its weakest ingredient. Thankfully, suppliers offering 3-pyridinemethanol, 5-amino- cater to practical research realities. For someone running a small lab, getting products shipped in manageable, stable quantities lowers the risk of spoilage and waste. Those in industrial settings benefit from scalable packaging—enough volume to keep batches running smoothly, but with clear labeling and documentation to ease regulatory scrutiny.

    Safe storage matters too. The compound holds up well under standard conditions, but keeping it in cool, dry environments extends shelf life and reduces nasty surprises. Handling instructions are straightforward for most chemists, but routine reminders about air and moisture sensitivity keep both staff and budgets safer over long projects. Staff at every level—from undergraduate interns to principal scientists—benefit when basic lab hygiene surrounds key reagents.

    Efficiency, reproducibility, and safety create a foundation for moving projects from concept to pilot stage. A research environment where chemists trust their chemicals spurs creativity. The lab stops being a zone of troubleshooting and starts transforming into a space for exploration, innovation, and progress.

    Challenges and Areas for Improvement

    No compound is perfect, and every chemical introduction carries trade-offs. Working with 3-pyridinemethanol, 5-amino- sometimes demands small adjustments to solvents or reaction temperatures. Researchers find minor solubility tweaks and sometimes need to adapt purification protocols—especially in reactions with tight selectivity windows. Yet, compared to more adventurous functional groups or unstable intermediates, these adjustments are usually straightforward. Past experiences in multi-step synthesis projects have taught that a compromise at the starting material stage is more manageable than wrestling with instability later on.

    Lab safety training needs to keep pace with any introduction of new chemicals. While 3-pyridinemethanol, 5-amino- exhibits manageable risk for those who observe standard laboratory procedures, frequent reminders about handling, disposal, and spill containment go a long way in keeping research environments healthy. Early conversations with environmental and safety officers catch potential issues before they move from minor irritations to major disruptions.

    Looking ahead, continuous improvement in supply chain transparency and batch reproducibility supports all levels of chemical research. Chemists remain hungry for process details—each change in supplier practice ripples outward, touching data reproducibility and wider environmental impact. In practice, labs choosing reliable sources and integrating supplier updates into standard operating procedures have an easier time with both quality assurance and staff training.

    Why 3-pyridinemethanol, 5-amino- Deserves Chemical Researchers’ Attention

    The rush to innovate keeps laboratories searching for better, more versatile chemical tools. From everyday assay development to advanced drug discovery, 3-pyridinemethanol, 5-amino- demonstrates its value by making complex steps more predictable and reducing headaches from impurities or hard-to-handle substances. My own research background leans heavily on building trust—not only with team members but with each component in the experimental chain. Reagents that consistently perform up to standard remove friction, letting energy and creativity flow toward breakthroughs instead of repeated troubleshooting.

    Having a go-to building block that behaves as expected encourages research teams to stretch beyond familiar boundaries. Instead of wrestling with unreliable ingredients, scientists can focus on exploring uncharted reaction space or pushing molecules toward ever more ambitious targets. For those invested in science that matters—whether bringing a new medicine to market or helping farmers adopt sustainable solutions—the difference adds up. People want to spend less time on quality control and more time on what pushes science, health, and technology forward.

    Moving Research Forward: The Final Word on Practical Intermediates

    Each breakthrough in chemistry builds on a mountain of daily decisions, small victories, and setbacks. In the crowded world of organic intermediates, 3-pyridinemethanol, 5-amino- stands out because it brings real benefits to both everyday research and bigger industrial goals. By combining a distinctive structure with solid supplier support, the compound tackles common pain points—purification bottlenecks, unpredictable yields, and slow regulatory approval. The labs that build success stories don’t just chase the latest hype; they make careful, informed choices about the tools and compounds they bring through their doors.

    In the end, chemistry brings real-world value through steady, incremental improvements, grounded in collective experience and honest feedback from those at the bench. Teams who consistently opt for high-quality, robust intermediates find themselves solving bigger challenges, faster and with fewer false starts. With compounds like 3-pyridinemethanol, 5-amino-, the pursuit of precision, reproducibility, and discovery continues—one reliable building block at a time.