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HS Code |
914517 |
| Chemical Name | 3-Pyridinemethanamine, 6-chloro- |
| Cas Number | 63592-90-3 |
| Molecular Formula | C6H7ClN2 |
| Molecular Weight | 142.59 |
| Iupac Name | 6-chloropyridine-3-methanamine |
| Appearance | Colorless to light yellow liquid |
| Solubility | Soluble in water and organic solvents |
| Inchi | InChI=1S/C6H7ClN2/c7-6-2-1-5(3-8)4-9-6/h1-2,4H,3,8H2 |
| Inchikey | RMQKPUJXYAUBGN-UHFFFAOYSA-N |
As an accredited 3-Pyridinemethanamine, 6-chloro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The packaging is an amber glass bottle containing 25 grams of 3-Pyridinemethanamine, 6-chloro-, with a tightly sealed screw cap. |
| Container Loading (20′ FCL) | 20′ FCL loaded with securely packed, sealed drums of 3-Pyridinemethanamine, 6-chloro-, meeting all safety and transport regulations. |
| Shipping | 3-Pyridinemethanamine, 6-chloro- is shipped in tightly sealed, chemical-resistant containers appropriate for amines, compliant with local and international regulations. Transportation is handled by certified carriers, with clear hazardous labeling and documentation. Temperature and handling precautions are maintained to ensure safe delivery. Shipping complies with DOT and IATA/IMDG standards. |
| Storage | 3-Pyridinemethanamine, 6-chloro- should be stored in a tightly sealed container, away from light, moisture, and incompatible substances such as strong oxidizing agents. Keep it in a cool, dry, and well-ventilated area, preferably in a chemical storage cabinet designed for organic compounds. Ensure proper labeling and restrict access to trained personnel to ensure safe handling and storage. |
| Shelf Life | The shelf life of 3-Pyridinemethanamine, 6-chloro- is typically 2–3 years when stored in a cool, dry place. |
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Purity 98%: 3-Pyridinemethanamine, 6-chloro- with purity 98% is used in pharmaceutical intermediate synthesis, where enhanced reaction yield and product consistency are achieved. Melting Point 60°C: 3-Pyridinemethanamine, 6-chloro- with a melting point of 60°C is used in API manufacturing, where reliable thermal stability during processing is ensured. Molecular Weight 142.59 g/mol: 3-Pyridinemethanamine, 6-chloro- having a molecular weight of 142.59 g/mol is used in fine chemical research, where predictable stoichiometric calculations are facilitated. Water Content ≤0.5%: 3-Pyridinemethanamine, 6-chloro- with water content not exceeding 0.5% is used in moisture-sensitive synthesis, where side reactions are minimized. Storage Stability at 25°C: 3-Pyridinemethanamine, 6-chloro- stable at 25°C is used in laboratory storage, where long-term compound integrity is maintained. Particle Size ≤100 µm: 3-Pyridinemethanamine, 6-chloro- with particle size ≤100 µm is used in catalyst preparation, where uniform dispersion in reaction media is achieved. Assay ≥99%: 3-Pyridinemethanamine, 6-chloro- with assay ≥99% is used in high-purity synthesis workflows, where product quality and reproducibility are improved. Residual Solvents ≤0.1%: 3-Pyridinemethanamine, 6-chloro- with residual solvents ≤0.1% is used in regulated pharmaceutical processes, where compliance to safety standards is secured. |
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Chemical research doesn’t stand still. In my years working around labs and speaking with researchers, I’ve seen a steady push toward useful, targeted molecules that can move an idea from bench to industry. A compound getting recent attention is 3-Pyridinemethanamine, 6-chloro-. It’s not some catch-all reagent you’ll find in every storeroom, but plenty of work depends on this versatile molecule as a building block and functional ingredient.
Ask most chemists what sets a high-quality compound apart, and you’ll hear plenty about purity, batch consistency, and trusted sources. 3-Pyridinemethanamine, 6-chloro- usually shows up as an off-white to light yellow powder. People turn to credible suppliers for material with high chemical purity, certified using NMR, HPLC, and mass spec. A solid sample brings a reliable melting point; most often, you’ll see specifications putting it in the 60–80°C range, but each batch carries a traceable certificate. In practice, researchers put a lot of trust in the numbers behind these reports, knowing shortcuts lead to wasted time and energy.
It’s not just about numbers on a sheet. Experience teaches you to look for clarity in appearance, ease of weighing, and proper packaging. Even a small speck of contamination, a cracked bottle, or label confusion can spoil work, and I’ve watched enough projects fizzle to say this matters more than you think.
3-Pyridinemethanamine, 6-chloro- isn’t a one-trick pony. Its structure—a pyridine ring, aminomethyl group, and a chlorine at the 6-position—makes it a toolkit favorite. Medicinal chemistry teams look to it as a core intermediate when piecing together new compounds. Adding a chlorine changes the game: you get unique reactivity, new routes for further substitution, and sometimes, surprisingly high activity in biological assays. That rings true for many candidates designed to block or stimulate receptors in the search for promising drugs. On the bench, reactions like amidation, acylation, and reductive amination come up often with this compound as the jumping-off point.
People working on complex molecules appreciate that the 6-chloro group adds a twist that simpler pyridyl amines don’t have. I’ve seen colleagues use it for making new agrochemical scaffolds too—especially compounds looking to tune resistance or stability in real-world settings. Materials scientists also keep an eye on compounds like this: sometimes, a new additive boosts performance or opens up fresh avenues for synthesis. It’s not unusual for specialized electronics research and coatings development to draw on these building blocks when small differences in structure make a big difference in function.
Chemistry turns on details. For those used to ordinary pyridinemethanamines, adding a chlorine at the 6-position transforms the game. This change doesn’t just add a halogen folks might check off on a list; it influences durablity, solubility in different solvents, and the way intermediates react further down the line. I’ve fielded late-night calls from junior researchers surprised to find that switching between the non-chlorinated and chlorinated variants led to completely new chemistry—and sometimes, far cleaner purifications.
Differences show up in both chemistry and safety. The electron-withdrawing power of the chlorine group can limit side reactions and help keep sensitive intermediates stable. This, in turn, gives teams a little breathing room in multi-step syntheses. Stop to compare spectra and you’ll see the fingerprints of these changes: shifts in NMR, altered fragmentation in mass spec, and differences in reactivity under mild or harsh conditions.
Some might ask if similar halogenated analogs—fluorine, bromine, iodine—offer the same perks. Experience says they don’t line up one-to-one. Chlorine’s atomic size, reactivity, and commercial availability deliver a sweet spot for many syntheses, whereas fluorine’s high electronegativity or iodine’s bulk introduce their own quirks and can drive up costs fast. As always, the choice needs to fit both the chemistry and the bottom line of a project.
Having 3-Pyridinemethanamine, 6-chloro- on hand gives research teams agility. In a small or mid-sized lab, teams constantly triage projects. Maybe you start with a classic pyridine, but a single substitution isn’t enough. That’s often when researchers reach for the 6-chloro version, adapting to emerging data or troubleshooting unexpected setbacks. Keeping good-quality supplies reduces scrambling and makes it easier to pivot.
There’s a familiar pattern in discovery: a compound shows a spark of activity, but properties like solubility or metabolic stability just aren’t there. Adding a chlorine at the right spot sometimes solves the problem, providing an anchor for further modification. You can see this in countless drug development programs—there’s a reason so many clinical candidates have carefully chosen halogen substitutions.
Sometimes, creative chemistry calls for building blocks that break the mold of “usual suspects.” Teams forced to work with only standard amines soon hit a wall; broader access to variants like 3-Pyridinemethanamine, 6-chloro- encourages a spirit of exploration. I’ve witnessed projects succeed after failing with traditional substrates, just by swapping in this molecule and watching the chemistry open up in new directions. That’s one lesson no algorithm can predict—the benefits of thinking a step past the ordinary.
Many universities and startups juggle priorities. Tight budgets often mean stretching stockrooms thin. At the same time, high-end synthesis needs depend on reliable, reproducible chemistry. The best way forward? Building relationships with trustworthy suppliers who test for known impurities, deliver technical support, and keep documentation air-tight. More than once, I’ve seen projects grind to a halt when a vendor changes batch protocols or slips on quality assurance. Reliable access builds real confidence. In life science startups, a single problematic intermediate can balloon costs and sap morale; consistency brings stability in both workflow and planning.
Sometimes, smaller labs feel left out from rapid innovation because sourcing specialty reagents turns into a hassle. Easy access to specialty amines, especially those like this one, breaks down barriers between idea and experiment. I’ve seen junior researchers at a university turn a new hypothesis into published data using a batch bought on relatively short notice. It closes the loop from curiosity to meaningful, peer-reviewed outcomes.
Drug hunters pay close attention to halogenated intermediates. In many stories behind approved medicines, you’ll find a tale of iterative synthesis—swapping, adding, and removing substituents in search of a hit. The chlorine at the 6-position brings tweaks in pharmacokinetics, can improve metabolic stability, and sometimes allows fine control over how a lead interacts with its biological target. Libraries of candidate compounds built from amines like this have seeded patents and fueled the rise of new healthcare approaches.
Materials scientists also value the freedom to tune subtle properties, especially when exploring niche electronics, catalysts, or functional coatings. Adding a halogen changes everything from film formation to temperature resistance. This particular amine fits into certain polymers and specialty resins where minor differences in starting materials swing performance in a big way.
Even if the molecule doesn’t headline every discovery, it plays a quiet but crucial supporting role in the foundation of new products. In my experience, the real breakthroughs come from consistent access to solid chemical building blocks. Over time, that compounds into a competitive edge—helping labs race from raw idea to market-ready application.
Storing and handling 3-Pyridinemethanamine, 6-chloro- won’t trip up an experienced team, but there’s always a learning curve. It’s an amine, so it’s best kept sealed away from air and moisture. You can count on that amine smell—the sort that sticks around a bit too long on gloves—and the usual set of safety expectations: eye protection, nitrile gloves, and a fume hood for weighing. More than once, I’ve chased a leaky cap or scrambled to clean up a bottle knocked sideways. A little respect for storage protocols avoids headaches.
Waste disposal matters too, especially in schools or shared spaces. Chlorinated organics follow their own paths through local waste streams and must be segregated from general non-halogenated waste. Following in-house rules and bundling open containers for proper disposal protects both people and the environment. In my own daily routine, I’ve found that careful cleanup and fast labeling take less time than searching for lost bottles or deciphering old handwriting.
Quality control is strong across many suppliers, but some pain points crop up repeatedly. Transparency about trace impurities tops the wish list for most research buyers. Knowing exactly what you’re getting—the peaks in the HPLC trace, any residual solvents, and possible cross-contaminants—prevents wasted time. I recall one project derailed by a persistent, unexpected impurity that showed up only after repeated rounds of analysis. Public sharing of analytic data in searchable databases could help match new chemists with trusted vendors.
Access to clear, up-to-date safety data, not just as tiny printouts but in reader-friendly summaries, would go a long way. Plenty of junior scientists benefit from shared wisdom collected in plain language. I’ve watched new hires avert disaster simply because someone left a checklist by the chemical cabinet—sometimes, small improvements in information flow bring big safety dividends.
On the labor front, smaller batch options make specialty reagents more affordable and less likely to go to waste on the shelf. Bundling purchase with in-depth technical support, whether by chat or phone, helps teams get up to speed with the quirks of each reagent. Some of the best conversations I’ve had with suppliers focused on troubleshooting synthetic bottlenecks that their product unexpectedly filled.
Research never stays static. People who want to push boundaries—whether in pharma, agriculture, or materials science—depend on building blocks like 3-Pyridinemethanamine, 6-chloro-. Every new project teaches us how small structural changes ripple through downstream chemistry, sometimes unlocking routes nobody expected. I’ve sat in on project reviews where a single successful amine substitution opened lucrative new patent space or let a team leap past a stalled synthesis. Those leaps don’t come from chance. They start with conscious choices about which reagents to invest in and which to set aside.
Projects progress chaotically: schedules slip, targets shift, priorities change. Labs that embrace flexibility rely on a variety of smart intermediates, including this one, to fill in the gaps between inspiration and finished product. It doesn’t just grease the wheels of chemistry—access to the right reagent supplies fosters a habit of creative problem-solving. The demands of modern R&D put a premium on both access and insight; it’s more than matching a CAS number, it’s about choosing reagents that serve as springboards.
No single compound forms the core of all discovery, but a well-chosen intermediate like 3-Pyridinemethanamine, 6-chloro- offers more than just a piece of a puzzle. It shows up as a trusted tool for building complexity, tackling real-world challenges, and encouraging research teams to act on fresh ideas. Over time, the small things—like a pure, well-documented, and reliable bottle of this amine—stack up. That’s how discoveries happen, one reaction at a time, powered by choices grounded in daily experience, careful attention, and honest relationships with suppliers.
From my own work and what I’ve seen in colleagues’ hands, 3-Pyridinemethanamine, 6-chloro- doesn’t just fill a line on a stockroom log. It fills a real need in chemical research and development, letting scientists bridge the gap between what’s possible and what works in practice. Investing in this molecule is an investment in the kind of flexibility and detail-oriented thinking that uncover the next breakthrough.