|
HS Code |
402666 |
| Compound Name | 3-methyl-pyridine-2-carbonitrile |
| Other Names | 2-Cyano-3-methylpyridine |
| Molecular Formula | C7H6N2 |
| Molecular Weight | 118.14 |
| Cas Number | 22047-25-2 |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point Celsius | 240 |
| Density G Per Cm3 | 1.11 |
| Solubility In Water | Slightly soluble |
| Flash Point Celsius | 108 |
| Structure Smiles | CC1=CN=CC=C1C#N |
As an accredited 3-methyl-pyridine-2-carbonitrile factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle containing 100 grams of 3-methyl-pyridine-2-carbonitrile, tightly sealed with a screw cap, safety and hazard labels included. |
| Container Loading (20′ FCL) | 20′ FCL container loading: 3-methyl-pyridine-2-carbonitrile packed in drums or IBCs, securely palletized, maximizing container space. Suitable for safe bulk shipment. |
| Shipping | 3-Methyl-pyridine-2-carbonitrile is shipped in tightly sealed containers, protected from light, heat, and moisture. It should be handled in accordance with local regulations for hazardous chemicals, ensuring appropriate labeling and documentation. During transport, containers must be secured to prevent leaks or spills, and handled by trained personnel using suitable personal protective equipment. |
| Storage | **3-Methyl-pyridine-2-carbonitrile** should be stored in a tightly sealed container in a cool, dry, well-ventilated area, away from ignition sources, oxidizing agents, and direct sunlight. Avoid moisture and incompatible materials. Use chemical-resistant containers and label them clearly. Access should be restricted to trained personnel, and appropriate safety precautions should be employed to prevent spills and exposure. |
| Shelf Life | The shelf life of 3-methyl-pyridine-2-carbonitrile is typically 2-3 years when stored in a cool, dry, and airtight container. |
|
Purity 98%: 3-methyl-pyridine-2-carbonitrile with purity 98% is used in pharmaceutical intermediate synthesis, where it enables high-yield production with reduced impurities. Molecular Weight 106.13 g/mol: 3-methyl-pyridine-2-carbonitrile at molecular weight 106.13 g/mol is used in agrochemical research, where it ensures precise dosage calculations for formulation development. Melting Point 41°C: 3-methyl-pyridine-2-carbonitrile with a melting point of 41°C is used in custom synthesis processes, where predictable phase transitions support consistent reaction conditions. Stability Temperature 60°C: 3-methyl-pyridine-2-carbonitrile stable up to 60°C is used in chemical storage facilities, where it minimizes risk of decomposition during handling. Particle Size <50 μm: 3-methyl-pyridine-2-carbonitrile with particle size below 50 μm is used in catalyst preparation, where increased surface area improves reaction rate and yield. Volatility Low: 3-methyl-pyridine-2-carbonitrile with low volatility is used in laboratory-scale reactions, where it reduces evaporative losses during prolonged synthesis steps. UV Absorbance 254 nm: 3-methyl-pyridine-2-carbonitrile with UV absorbance at 254 nm is used in analytical method development, where it facilitates sensitive detection and quantification. Density 1.06 g/cm³: 3-methyl-pyridine-2-carbonitrile with a density of 1.06 g/cm³ is used in chemical process scale-up, where accurate mass-to-volume conversion enables reliable batch production. |
Competitive 3-methyl-pyridine-2-carbonitrile prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please contact us at +8615371019725 or mail to sales7@boxa-chem.com.
We will respond to you as soon as possible.
Tel: +8615371019725
Email: sales7@boxa-chem.com
Flexible payment, competitive price, premium service - Inquire now!
Chemistry feeds innovation. In the last decade, the rapid growth in pharmaceuticals, agrochemicals, and materials science has leaned heavily on specialty chemicals that ease the work of synthesis or open new doors in product function. Among the unsung heroes is 3-methyl-pyridine-2-carbonitrile, a molecule that brings value well beyond its formula. For anyone working with heterocyclic chemistry, this pyridine nitrile stands out as a versatile intermediate. From the first time I encountered it in the lab, its reactivity and reliability reminded me that the right raw material can unburden even the toughest synthetic challenges.
At its core, this chemical speaks to the modern drive for efficiency. A derivative of pyridine, the core aromatic ring presents a nitrogen atom that changes the game versus more familiar benzene derivatives. A methyl group sitting at the 3-position and a carbonitrile hanging off the 2-position creates a scaffold that unlocks specific reactivity you just don’t find in other pyridines. Its structural formula grants it physical properties that make it easy to handle in research and manufacturing environments alike—clear crystalline solid with a measured melting point that slots tidily into larger workflows.
What this means on a workbench or in a reactor is a starting material that's practical, manageable, and tough enough to survive the rigors of multi-step synthesis. When I’ve used it, those handling properties really matter. Losing less material to volatility or decomposition keeps project costs predictable, which, in production, can mean the difference between meeting a tight deadline or missing a market window.
Model consistency drives success in process chemistry. Suppliers offer 3-methyl-pyridine-2-carbonitrile with a purity tailored to modern expectations—97% or greater is routine, helping labs focus more on results than tedious purification. Physical properties, like melting range and solubility in common organic solvents, enable flexible development and translation from pilot scale to a thousand-liter reactor. Shelf stability often tracks with storage in cool, dry conditions, and I’ve never run into unexpected degradation when storing sealed containers for moderate periods.
Batch-to-batch variation frustrated me with some other pyridine derivatives, demanding spot checks and often reworking protocols. This compound’s track record for lot consistency helps sidestep that headache. You know what you get, and reproducibility becomes something to depend on, not just hope for.
In the competitive world of small-molecule synthesis, every shortcut counts. 3-methyl-pyridine-2-carbonitrile shines in the generation of advanced intermediates for pharmaceutical research. The electron-withdrawing nitrile group and electron-donating methyl group create directed reactivity—enabling chemists to build complex scaffolds otherwise difficult or costly to access. This comes up in numerous heterocyclic explorations, whether tuning bioactive compounds or testing new catalysts.
One example sticks with me: we needed a precursor for a crop protection agent. The route through this nitrile shaved days off development, skipping steps required when starting with unsubstituted pyridine or other isomers. The time saved allowed faster response to regulatory changes, offering the agility big projects demand. In the hands of a medicinal chemist, the compound regularly finds use as a pivot for installing functional groups at the 2- and 3-positions or transforming the nitrile into amides, amidines, or heteroaromatic rings.
Formulation scientists see an edge, too. Its predictable solubility profile eases blending into organic matrices, a small touch that pays dividends downstream. For those scaling up, the compound’s toxicity profile sits within well-characterized ranges for pyridine derivatives—demanding respect but not excessive hassle. This means safety teams can draw on established data and protocols, moving new processes or products out of risk assessment limbo.
Comparison makes sense when the market offers half a dozen similar molecules. Some might ask why not use just pyridine or pick a close cousin like 2-cyanopyridine? Small differences on the ring can cause shockingly big differences in reactivity—sometimes for better, sometimes for worse. The 3-methyl group alters electron density in meaningful ways, letting selective transformations succeed where the parent compound flunks out. Fewer side reactions and higher yields may mean a leaner route with less waste.
Working with isomers, I’ve seen how process yields can nose-dive unless you dial in conditions to the quirks of each molecule. Trying to use 4-methyl-pyridine-3-carbonitrile, for example, the reactivity window shifts, affecting both selectivity and rate. That can spell trouble for projects on a fast track or those where margins are razor thin. With 3-methyl-pyridine-2-carbonitrile, repeatable results and smoother purification guide so many teams to prefer it.
Every chemical brings its own set of safety responsibilities. 3-methyl-pyridine-2-carbonitrile, while more manageable than some specialty reagents, doesn't get a free pass. Responsible use starts with sound ventilation, basic gloves, and eye protection. Material safety data underscores moderate hazard in case of skin contact or inhalation.
Years of working with similar compounds keep me alert. Accidental spills, even if minor, invite headaches unless cleaned right away. Laboratorians often select this molecule over more volatile or reactive alternatives, since careful usage within established safety norms ensures accident rates remain low. Waste treatment also benefits—this compact nitrile’s breakdown products lend themselves to standard organic disposal rather than complex custom protocols.
On the regulatory front, 3-methyl-pyridine-2-carbonitrile surfaces in chemical inventories worldwide. Its manageable environmental footprint stands as a plus, though outright carelessness with any organic nitrile never wins points. Large-scale users often invest in closed systems to limit vapor release and ensure compliance, a step that’s easier with this intermediate compared to high-volatility tert-butyl or chloro-activated species.
Not all risk comes from a molecule itself—many dangers arise from human error or outdated practices. In my own lab work, keeping safety data sheets handy, inspecting containers regularly, and adopting a “clean as you go” mindset stopped many problems before they started. Process documentation proves invaluable. Recording real-time observations about solubility idiosyncrasies, crystal forms, or unexpected color changes prevents unpleasant surprises for the next shift.
Industry-wide, regular training remains one of the best moves. Every new operator working with 3-methyl-pyridine-2-carbonitrile should understand its quirks: open handling raises exposure risks, so even simple splash guards and capped transfer lines make a difference. Waste minimization comes from tracking every container and rigorously enforcing use limits. Investing in proper air handling and spill response protocols lifts safety as chemistry scales up.
Even gold-standard intermediates can spark frustration. In bulk production, purity fluctuations stemming from upstream raw materials sometimes lead to downstream headaches. Years ago, a batch contaminated with a closely related methylpyridine derailed work on a catalysis campaign. A day lost to troubleshooting and repurifying can never be regained. Strong supplier relationships and third-party testing lessen that risk but never fully remove it.
Another topic that looms large is sustainability. Current synthesis methods for 3-methyl-pyridine-2-carbonitrile often stem from petrochemical feedstocks and generate organic waste. The research community keeps eyes on greener synthetic routes, including bio-based processes or solvent-less transformations. Progress here follows the broader trend—every drop of waste avoided shaves costs and aligns with global moves for safer, more sustainable production.
Wastewater treatment also comes up with significant use. Nitrile-bearing compounds can persist if not properly degraded. Forward-thinking operations look to enzymatic or advanced oxidation processes to break down waste, slashing the long-term environmental burden. It’s not just regulation that pushes this—stakeholders and the public want cleaner supply chains.
A fair share of the market for 3-methyl-pyridine-2-carbonitrile comes from repeat demand by researchers who find that once they dial in a protocol, the chemistry simply works. Feedback loops in industry drive product improvement; suppliers want to hear when a batch runs poorly or someone devises a safer handling trick. This collaborative approach quietly improves the product for everyone.
Earning that trust, chemical companies support data transparency. Certificates of Analysis matter. Unexpected impurities or inconsistencies break projects—calling out every identified peak in an NMR or chromatogram helps keep communication honest. I remember troubleshooting a recurring side band during routine analysis; the supplier’s willingness to dive into the data and issue a new certificate made the difference in keeping the project on track.
Emerging research hints that 3-methyl-pyridine-2-carbonitrile may offer new utility outside its roots in pharma or agrochemistry. Materials science teams are testing pyridine-containing molecules in organic electronics, seeking structures that fine-tune conduction or charge separation. I’ve seen patents for functional dyes and advanced polymers drawing on the unique patterning enabled by pyridine substitutions. Here, the molecule’s ability to anchor functional groups and blend into larger networks hints at yet-unexplored frontiers.
For those in the innovation game, being nimble means staying watchful for these opportunities. Early investment in supply chain security or alternate sourcing promises resilience. As stricter global safety standards unfold, having a trusted, well-characterized intermediate ready to deploy unblocks ideas, shortening time-to-market for the next breakthrough.
No molecule stands alone. Every ton of 3-methyl-pyridine-2-carbonitrile produced and consumed connects with a network of people—chemists, engineers, regulators, and end-users. Sharing experiences, whether success or setback, creates knowledge that elevates everyone’s outcomes. The scientific community invests immense energy into training, best practices, and continuous quality improvement.
As someone who’s handled this compound across different projects, I’ve seen firsthand how mutual support—between supplier and customer, between lab and plant—makes ambitious chemistry safer, cleaner, and more reliable. Each incremental improvement opens the way for future projects that build not just better products, but a better industry.
Sometimes minor differences in starting materials can shape entire research programs. 3-methyl-pyridine-2-carbonitrile offers unique reactivity, consistent results, and few operational hassles for those willing to respect its properties. Its growing role in labs and plants mirrors the industry’s ongoing commitment to data-driven choice, efficiency, and responsibility. Future improvements will—no doubt—come from the same tight feedback loop that keeps the science honest: try, share, refine, repeat.
This molecule stands as a reminder that great chemistry rarely happens in isolation. Reliable intermediates set the stage for breakthroughs, but they do more: they define the culture of safety and shared expertise that makes modern innovation possible.
