3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine

    • Product Name: 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine
    • Chemical Name (IUPAC): 3-methyl 4-(3-methoxypropoxy)-2-(hydroxymethyl)pyridine
    • CAS No.: 884495-35-6
    • Chemical Formula: C12H19NO3
    • Form/Physical State: Liquid
    • Factroy Site: No.968 Jiangshan Rd., Nantong ETDZ, Jiangsu, China
    • Price Inquiry: sales7@bouling-chem.com
    • Manufacturer: Nantong Acetic Acid Chemical Co., Ltd.
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    Specifications

    HS Code

    767963

    Chemical Name 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine
    Molecular Formula C12H19NO3
    Molecular Weight 225.29 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point Estimate: 340-350°C (may vary with pressure)
    Solubility Soluble in organic solvents; low water solubility expected
    Density Approx. 1.07 g/cm³ (estimated)
    Purity Typically >98% (commercial sample)
    Storage Conditions Store in a cool, dry place, tightly sealed
    Flash Point Estimated >100°C
    Refractive Index Approx. 1.495 (estimated)
    Functional Groups Pyridine, methyl, methoxypropoxy, hydroxymethyl

    As an accredited 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250g white plastic bottle, tamper-evident cap, chemical label with compound name, purity, hazard symbols, manufacturer, and batch number.
    Container Loading (20′ FCL) 20′ FCL loaded with sealed drums of 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine, compliant with safety and export regulations.
    Shipping **Shipping Description:** 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine should be shipped in tightly sealed containers, protected from moisture and light. Transport under ambient temperature with appropriate labeling as a laboratory chemical. Follow all local, national, and international regulations regarding hazardous materials. Ensure all documentation and safety data accompany the shipment.
    Storage Store **3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine** in a tightly sealed container, kept in a cool, dry, and well-ventilated area. Protect from light, heat, moisture, and incompatible substances such as strong oxidizers. Clearly label the container and keep away from food or drink. Use secondary containment to prevent leaks, and ensure access to appropriate spill control and safety equipment.
    Shelf Life Shelf life: Store in a cool, dry, and dark place. Stable for 2 years under recommended storage conditions in sealed containers.
    Application of 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine

    Purity 98%: 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine with purity 98% is used in pharmaceutical intermediate synthesis, where high purity ensures consistent reaction yields.

    Melting Point 78°C: 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine with a melting point of 78°C is used in solid dosage form formulation, where controlled melting benefits processing efficiency.

    Molecular Weight 223.27 g/mol: 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine with a molecular weight of 223.27 g/mol is applied in medicinal chemistry research, where precise molecular mass supports accurate compound design.

    Solubility in DMSO: 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine soluble in DMSO is used in biological assay preparation, where clear solutions enable reliable test reproducibility.

    Stability Temperature 45°C: 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine stable up to 45°C is used in storage and transport, where thermal stability maintains product integrity.

    Particle Size <50 µm: 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine with particle size less than 50 µm is used in fine chemical blending, where improved dispersion enhances mixture homogeneity.

    Assay 99%: 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine with an assay of 99% is used in high-purity reagent manufacturing, where minimal impurities lower side reaction risks.

    LogP 1.2: 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine with LogP 1.2 is used in drug discovery screening, where balanced lipophilicity improves compound bioavailability profiling.

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    Certification & Compliance
    More Introduction

    Introducing 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine: A Perspective from the Manufacturing Floor

    Real-World Value Grounded in Chemical Expertise

    In our industry, trends rise, questions surface, and often the right answer comes down to practical experience. Let’s look at 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine. You might see names like MMPHMP or similar shorthand bouncing around, but what matters to us every day under the roof of our own facility is how this compound behaves, why it matters, and the real edge it brings compared to other building blocks in the pyridine family.

    What We Are Actually Dealing With

    Synthesizing 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine means taking raw, carefully sourced feedstocks and walking a tangible path through several process stages: catalysis, separation, purification, and intensive in-process testing. The result? A finely tuned crystalline or powdered product that takes on a pale hue and stands up to the sorts of validation checks our clients demand. From purity assays to residue solvent analyses, every batch tells a story from start to finish. Direct experience with this pyridine derivative has taught us a few hard truths about what control really looks like and how even minor impurities can throw downstream applications off balance.

    Some products carry names that resemble ours, but side-by-side comparisons highlight clear distinctions. 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine carries unique electron-donating and -withdrawing groups. That backbone—one methyl, one methoxy propoxy, one hydroxymethyl—translates directly into the compound’s physical and chemical behavior. Molecular architects notice subtle differences in solubility across polar and non-polar media or in thermal stability not shared by other substituted pyridines. These characteristics weren’t guessed at; we’ve observed them through dozens of production cycles, in pilot reactors and final reactors, and during routine troubleshooting.

    Molecular Features and Real-World Performance

    Central to our ongoing research is the methyl group at position three, flanked by the bulkier methoxy-propoxy substituent. That shift alone, from a straight methoxy to a methoxy-propoxy tether, has given chemists working in drug discovery or synthesis toolkits new leverage. It’s not just about the binding profiles or reactivity in textbooks—batch variations and subtle impurities play bigger roles than many would expect. Our lab teams invest serious resources into maintaining tight specification windows, not because of regulatory dogma but because our partners rely on uninterrupted performance in scaled syntheses and active ingredient projects.

    Comparing this compound directly with parent pyridines or similar derivatives, we have tracked a consistently improved solubility in mixed phase applications and a markedly higher compatibility with certain base-catalyzed downstream reactions. Chemists who lean on results rather than announcements know the difference after a few production runs—higher batch yields, fewer unreacted residues, cleaner filtrations. These points might sound technical, but the lessons stick with anyone who has watched expensive downstream losses because of upstream inconsistencies.

    Specification Choices That Actually Solve Problems

    We approach each new synthesis with realism. Many in the chemical arena cut corners, shifting attention to demo-scale success, but this doesn’t get you repeat customers or reduce plant headaches. With 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine, we focused on minimizing isomeric contamination and maintaining a water content that made the product both manageable for end-users and shelf-stable during international shipping. Each drum or bag comes from a validated batch record—no exceptions for “off spec” lots.

    What does this focus look like in actual data? High-performance liquid chromatography (HPLC), nuclear magnetic resonance (NMR), and Karl Fischer titration back up the numbers. Not just for the sake of certificates, but because we have faced the reality of reworking product when a sigma slips. Several clients in pharmaceutical intermediates have relied on our ability to fulfill custom thresholds for residual solvents or provide custom particle sizing for their particular reactors. We’ve learned over time that these minor adjustments reduce unplanned downtime and smoothen the overall supply chain. Our experience says that post-production screening does not simply serve auditors—it drives up throughput farther down the chain.

    Usage Patterns Across Different Sectors

    Users in pharma research, advanced material development, and fine chemical synthesis have gravitated toward this compound for several reasons. Pyridine derivatives underpin whole classes of compounds in active pharmaceutical ingredients, enzyme inhibitors, and even some new-generation agrichemicals. The unique substitution pattern—3-methyl, 4-(3-methoxy propoxy), and 2-hydroxymethyl—creates opportunities for selective activation, especially in multi-step syntheses where controlled reactivity with other nucleophiles or electrophiles is essential. This isn’t abstract theory; several programs aimed at new CNS drugs and emerging antibiotic classes cite this exact molecule as a lynchpin synthon.

    Another sector benefiting from this compound’s profile is advanced coatings and specialty polymers. The aromatic nitrogen, paired with the flexible alkoxy side chain, allows formulators to design linkers that introduce hydrophilic spots in otherwise hydrophobic matrices. We have supported R&D teams looking for ways to tweak conductivity, permeability, or adhesion using molecular fragments derived from our product. Most chemical intermediates face trade-offs—one advantage gives up another. Here, our process balances reactivity with shelf stability, so formulators can develop products with longer lifespans and more reliable physical properties.

    Distinguishing Features vs. Other Pyridine Derivatives

    Industry experience says not all pyridines behave the same. Side substitutions shift pKa, alter metabolic fate, and, most critically for industrial manufacturing, change safety profiles and shelf-life risks. Comparing 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine to simple methylated pyridines or even familiar 2,4-disubstituted analogues, we have logged a suite of benefits: reduced volatility, easier purification via crystallization, and greater handling safety due to lower acutely toxic byproduct formation during routine operations. Lab techs and process chemists confirm these differences with every batch, often corroborated by lower waste volumes during downstream purification.

    Several downstream industries voice frustration when synthetic intermediates shift slightly in profile batch-to-batch. Our plant’s tracked experience shows our process for this particular compound keeps lot-to-lot variability in dissolution rates, impurity patterns, and shelf stability to a minimum. This hands-on benefit trumps marketing claims from resellers who rarely follow compounds from synthesis through to final blend integration. The direct effect? Fewer downstream reworks, less wasted time, and robust documentation in support of regulatory filings.

    Sourcing and Process Control: Lessons from the Plant

    Controlling the quality and repeatability of 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine demands persistent attention to raw material quality, equipment maintenance, and analytics. We operate reactors and separation equipment designed for easy containment and minimize cross-contamination risks, especially vital in multi-product facilities. Real-world lessons came hard: batches that failed for lack of moisture control or low-temperature crystallization errors never saw outgoing shipment. Every control point downstream, from filtration to packaging, pulls from these lessons. The proof lies in customer returns—nearly nonexistent for this product line compared with broader pyridine or substituted aromatic series.

    Sticking to tight process windows isn’t just for big clients. Mid-sized and emerging players approach us with project briefs expecting the same standards as major multinationals. Experience shows the effort pays off. Word spreads quickly when critical mass demanders of specialty pyridine derivatives neither experience delays nor reject lots due to variances in melting range or off-odors. On the plant floor, technicians routinely tighten protocols for every batch. That discipline is not a reaction to a single recall or non-conformance report; it comes out of dozens of reworks and loss analyses. The result is a culture that values reproducibility, and the process improvements have helped us ship this specific product to more regions and more diverse end-use cases without a hitch.

    Environmental and Regulatory Focus

    For those in regulated industries, the safety and sustainability of intermediates matter as much as their synthetic performance. Our process for 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine draws on tried-and-true engineering controls: closed-system synthesis, in-process air scrubbing, solvent recycling, and rigorous effluent treatment. The chemical structure itself offers some advantages over more volatile pyridine analogues, which drives down potential emissions and operator exposure in the factory. Hands-on experience reminds us that regulatory compliance is ongoing work, not a box to tick at the start.

    Many regulatory audits have occurred on our lines, evaluating MSDS support, process documentation, and traceability of incoming and outgoing shipments. These pressures have improved our procedures, and the fact that this compound consistently meets export documentation standards builds trust with new and returning clients alike. Driving this compliance forward means no daily shortcuts. We have invested in analytics, staff training, and data-backed continuous improvement, keeping claims transparent and preventing the sort of non-conformances that damage reputations and bottom lines.

    Supporting Innovation with Reliable Chemistry

    Our position as a direct manufacturer, not a middleman, means our teams see the challenges and successes firsthand. Partners in drug discovery or advanced manufacturing count on reagents they can trust, made by producers who live with the results of every production step. Innovation thrives on dependable building blocks. Over years of hands-on production experience, 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine has repeatedly supported both routine processes and demanding research programs that need confidence in their synthetic routes.

    Every inquiry into our compound brings fresh application questions. Some seek new routes to active pharmaceutical candidates. Others aim to fine-tune final material properties for electronics, coatings, or specialty adhesives. Our R&D contacts often run side-by-side comparisons of our product with similar intermediates, tracing differences in reactivity, shelf life, and cleanup requirements. We follow test results and, where needed, provide batch samples for pilot-scale validation. This open, iterative approach sharpens outcomes for everyone—manufacturers can scale safely, while innovators can push the boundaries of their own chemistry.

    Moving Forward: The Role of Experience and Data

    Years of direct production and in-house research build a unique perspective on the value of real chemical data. Feedback loops between plant, lab, and partners have taught us where standard specs fall short. Keeping the cycle of feedback open, we review field test results and lab data, incorporating practical adjustments that improve impurity profiles or shelf stability. Year after year, these changes shape a more robust product, directly informed by end-users’ experiences and our own day-to-day operations.

    Commercial chemistry rarely stands still. New analytical technologies and market shifts make yesterday’s production protocols less reliable over time. We meet this challenge head-on, updating purification steps and introducing new online QC tools that prevent recurring contamination issues. This compound has seen generational upgrades in our plant as better solvent management and enhanced process controls have reduced input waste and improved throughput. These investments, born from lessons on the line, offer tangible improvements to every client that counts on consistent, repeatable outcomes.

    Customer Collaboration: Building on Real Needs

    Fundamental to our business is direct conversation with customers. Each project, whether routine or novel, presents a unique set of technical and logistical needs. We listen, not just transact. Application testing frequently circles back into our production cycles, with process changes validated not in a boardroom but through pilot batches and advanced analytics. That hands-on, adaptive approach has let us refine our product until it meets both anticipated and emerging needs, well beyond a simple certificate or standard compliance.

    We understand that purchasing from a manufacturer means more than getting a drum delivered. It means partnering with a team that knows its product from reactor to warehouse dock and can respond with practical changes if outcomes drift from expectations. Whether supporting scale-up or helping customers adapt raw input profiles for tighter regulations or new synthesis routes, our perspective draws from decades of generational chemical manufacturing experience, on every shift and every batch.

    The Bottom Line: Why 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine Matters

    Over many years, 3-Methyl 4-(3-Methoxy Propoxy) 2-Hydroxymethyl Pyridine has supported innovation across a wide landscape of industries. From its tailored molecular balance to its behavior in actual plant conditions, this compound stands out not because of theoretical hype, but because daily production and rigorous analytics have proven its worth. Differences in purity, solubility, and downstream usability stem from process refinements, made possible through focused investment in plant technology, ongoing operator training, and a culture that values hard-won experience.

    Users looking for a reliable, differentiated pyridine derivative find practical advantages in our offering. Whether the need is precise reactivity, consistent batch-to-batch performance, or confidence in regulatory compliance, these priorities drive every operational decision in our plant. Between technical support and direct troubleshooting, we see success measured not only in shipped tons but also in the ongoing loyalty of the partners who trust us—batch after batch, project after project. Working with real materials, we see every day how smarter production, sharper analytics, and honest feedback build a compound’s reputation more powerfully than any spreadsheet or marketing campaign.