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HS Code |
854035 |
| Product Name | 3-Amino-5-bromo-2-fluoropyridine |
| Molecular Formula | C5H4BrFN2 |
| Molecular Weight | 207.00 g/mol |
| Cas Number | 183982-14-1 |
| Appearance | Off-white to light yellow solid |
| Melting Point | 98-102°C |
| Purity | Typically ≥98% |
| Solubility | Soluble in organic solvents such as DMSO and DMF |
| Storage Condition | Store at room temperature, in a cool, dry place |
| Smiles | c1c(cnc(c1Br)N)F |
| Inchi | InChI=1S/C5H4BrFN2/c6-3-1-4(8)9-2-5(3)7/h1-2H,8H2 |
As an accredited 3-Amino-5-bromo-2-fluoropyridine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 3-Amino-5-bromo-2-fluoropyridine, 5g, is supplied in a sealed amber glass bottle with a tamper-evident screw cap. |
| Container Loading (20′ FCL) | **Container Loading (20′ FCL):** 3-Amino-5-bromo-2-fluoropyridine securely packed in drums or fiber cartons, maximizing container space, compliant with export regulations. |
| Shipping | 3-Amino-5-bromo-2-fluoropyridine is shipped in airtight, chemically resistant containers, clearly labeled with hazard information. The package is cushioned and sealed to prevent leaks and exposure. It is transported following relevant regulations for hazardous chemicals, ensuring compliance with safety, handling, and documentation requirements for prompt and secure delivery. |
| Storage | Store **3-Amino-5-bromo-2-fluoropyridine** in a tightly sealed container, in a cool, dry, and well-ventilated area, away from direct sunlight and sources of ignition. Keep it separate from incompatible substances such as strong oxidizing agents. Ensure the storage area is equipped for chemical handling and labeled appropriately. Maintain at ambient temperature and protect from moisture to preserve its stability. |
| Shelf Life | 3-Amino-5-bromo-2-fluoropyridine typically has a shelf life of 2-3 years when stored in a cool, dry place. |
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Purity 98%: 3-Amino-5-bromo-2-fluoropyridine with purity 98% is used in pharmaceutical intermediate synthesis, where it ensures high yield and minimal byproduct formation. Melting Point 70°C: 3-Amino-5-bromo-2-fluoropyridine with a melting point of 70°C is used in solid-formulation processes, where it facilitates easy handling during manufacturing. Molecular Weight 208.98 g/mol: 3-Amino-5-bromo-2-fluoropyridine with a molecular weight of 208.98 g/mol is used in agrochemical active ingredient development, where accurate dosage calculations are supported. Particle Size <10 μm: 3-Amino-5-bromo-2-fluoropyridine with particle size less than 10 μm is used in advanced material research, where it enables homogeneous dispersion in polymer matrices. Stability Temperature up to 120°C: 3-Amino-5-bromo-2-fluoropyridine with stability up to 120°C is used in high-temperature organic synthesis, where thermal degradation is minimized. Water Solubility <0.5 mg/mL: 3-Amino-5-bromo-2-fluoropyridine with water solubility less than 0.5 mg/mL is used in heterocyclic compound library screening, where precipitation is avoided in organic solvents. Chromatographic Purity 99%: 3-Amino-5-bromo-2-fluoropyridine with chromatographic purity of 99% is used in medicinal chemistry lead optimization, where analytical consistency enhances screening reliability. |
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3-Amino-5-bromo-2-fluoropyridine stands out as the kind of specialty chemical you hear about in labs, production lines, and industry chatter between chemists always hunting for the next reliable building block. You get a bunch of molecules milling around out there, each with its quirks, uses, and success stories. This one lands itself on the short list for teams developing complex pharmaceutical compounds and advanced materials. I’ve seen plenty of cases where supply bottlenecks or wavering product reliability have left researchers stuck; with a compound like this, those issues start losing ground to consistency and adaptability. What’s inside the bottle shapes how new medicines reach the patients who need them, how novel agrochemicals fight pests, and how next-generation materials come to life in electronics. That matters more in practice than any sales pitch or datasheet gloss.
The backbone of 3-Amino-5-bromo-2-fluoropyridine isn’t complicated to sketch for a trained eye—one fluorine and one bromine atom decorating a pyridine ring, anchored by an amino group. The real story hides in how these groups play together. A halogen like fluorine tightens molecular stability and makes downstream reactions more selective; bromine, on the other hand, opens up options for coupling chemistry, letting chemists plug in new groups like puzzle pieces. Those who’ve worked through nights trying to shoehorn stubborn intermediates into new reactions understand the frustration that a less-versatile molecule creates. This one doesn’t throw up those barriers as often. The interplay between bromo and fluoro substitutions gives rise to a platform for Suzuki, Buchwald-Hartwig, or Ullmann couplings without endless tweaking or running test batches that lead nowhere fast.
Some fine chemicals look good on paper but stumble in actual bench work. You might notice products out there promising easy integration into synthesis steps, but they drag in unexpected side reactions or flake out under reaction conditions. This compound keeps its cool through a range of process environments—meaning, fewer headaches for chemists, lower troubleshooting costs, and less time lost during optimization. Having handled breakdowns in pilot plants and seen budgets balloon from seemingly small inconsistencies, I put a premium on resilience like this. What you want lining your shelves is a molecule ready to pull its weight during late-night experiments, scale-up trials, and regulatory validation—not just a pretty structure on a spec sheet.
Pharmaceutical development is not just about churning out blockbuster drugs; it depends on nimble, reliable intermediates like 3-Amino-5-bromo-2-fluoropyridine that let scientists fail fast and refine faster. From cancer therapies and CNS modulators to emerging antiviral scaffolds, this building block supports synthesis routes that hand over diversity and fine control. Medicinal chemists use it to add new twists to heterocyclic frameworks. Early-stage scale-ups appreciate that its chemical behavior doesn’t change under higher volumes, and analytical teams benefit from predictability in NMR and mass spectrometry profiles. That means faster regulatory documentation, clearer analytical trails, and cleaner data for patent submissions.
Agrochemical researchers also find value here. Plant protection agents and next-generation insecticides demand scaffolds tuned for both activity and environmental persistence—sometimes with tailored halogen patterns and amino functionality. Counting on a compound with both proven supply and trustworthy reactivity becomes a strategic decision, not just a technical one. Having worked in the demanding timelines of crop protection projects, I know the sting when an unreliable intermediate knocks progress off track just ahead of a demonstration trial.
Then comes specialty materials. Electronics and OLED manufacturers have a soft spot for pyridine cores with strategic halogen and amino groups. Thermal stability, purity, and minimal contamination aren’t academic—they make the difference between functional devices and costly rejections at quality control. A supplier who puts quality front and center adds true value, letting material scientists move from lab-scale proof-of-concept to viable products on shelves—without surprise setbacks.
The battle over purity is never-ending. Any chemist who’s had to clean up a noisy chromatogram or trace subtle impurities knows how fast confidence erodes. For 3-Amino-5-bromo-2-fluoropyridine, labs report consistently high purity, often above 98% by HPLC and NMR, even as production volumes scale up. That kind of result doesn’t happen by accident. Vendors who make quality control a real priority—sourcing high-grade raw materials, using validated synthesis protocols, double-checking output through modern analytics—reduce unpleasant surprises. Over the years, I’ve found that the upfront investment in reliable product pays off. Rework costs sink, repeated purifications fall off, and the conversation shifts from troubleshooting to innovating.
It’s easy to treat chemistry as something neat and isolated on a lab bench. But scaling up, you quickly learn how every extra impurity or batch inconsistency ripples outward—affecting mixing, filtration, or even regulatory paperwork. The journey from milligrams in glassware to kilograms in reactors can break projects if intermediates can’t handle the pressure. I’ve stood in process suites where unexpected foaming, color changes, or exothermic profiles from off-the-shelf intermediates triggered unplanned downtime. A molecule like this, documented and trusted through many scale-ups, doesn’t just drop your risk—it keeps timelines on track. Having predictable density, melting range, and solubility means equipment is easier to clean, processes run smoothly, and teams can forecast resource needs without layers of contingency planning.
Training new staff also benefits. Straightforward handling and proven safety data (with sensible storage and standard PPE) set up teams to move confidently. Nobody wants a “mystery box” on the shelf—especially in environments governed by Good Manufacturing Practice and regulatory oversight. Detailed certificates of analysis and traceable batch histories allow QA/QC to do their jobs properly and let production staff focus on making product, not firefighting.
The catalog pages for pyridine derivatives stretch on. Yet, only a subset combine high functional group tolerance, robust supply chains, steady price points, and documented performance in demanding syntheses. Many competitors offer single-halogen pyridines or unadorned aminopyridines. These alternatives hit walls when chemists need both selectivity and functional compatibility for downstream cross-couplings or derivatizations. Through my own collaborations, I’ve seen less functionalized analogues force extra reaction steps, create waste, and rack up regulatory headaches.
Some suppliers try to score points with ultra-high-purity versions, but these often come at a premium cost with diminishing returns for most applications. Others lower prices by trimming process controls, leading to inconsistent lots and longer qualification cycles. 3-Amino-5-bromo-2-fluoropyridine threads the needle—balancing accessibility with performance. Any research team with tight budgets, looming deadlines, and a mission to move ideas forward without compromise, finds that difference meaningful. It’s about time and confidence, not just molecular structure.
Nobody likes being held hostage by one supplier, especially after investing months qualifying an intermediate. Today’s global supply chains face real threats—natural disasters, shifting regulations, geopolitical crosswinds. A well-regarded supplier network, with local warehousing, multi-site production capability, and clear documentation, keeps projects moving. I’ve witnessed first-hand the scramble that starts when an intermediate becomes backordered without warning. Your project, once ahead of schedule, suddenly begins fighting to recover lost ground. With a proven compound like 3-Amino-5-bromo-2-fluoropyridine, security of supply isn’t wishful thinking. Teams gain clarity—whether for gram-scale R&D or commercial deployment—and can justify ordering extra material with less risk of write-off if plans change.
Modern chemistry comes with real-world responsibilities. Beyond just shipping bottles and stacking invoices, producers who put thought into greener processes, safer reagents, and responsible waste management help push the entire field forward. 3-Amino-5-bromo-2-fluoropyridine sits at the intersection where efficient synthesis meets sustainability. Availability of greener production protocols—reducing harsh solvents or embracing recyclable catalysts—means customers aren’t forced to choose between quality and conscience. Regulatory attitudes now demand traceability for origins, waste, and even carbon intensity. Proactive suppliers share process transparency, giving buyers the tools they need for compliance, safer handling, and better workplace hygiene. As someone who’s dealt with audits and internal reviews, I know peace of mind is worth more than a lower per-kilo cost. This mindset reflects how chemistry should be practiced—in accountability to our teams and the world outside.
No one expects to have every answer lined up before a project starts. The reality of modern science means confronting setbacks, needing odd documentation, or coming up against unexpected interactions in the lab. Top-tier suppliers back their compounds with responsive support, often staffed by people who’ve hammered out their own PhDs and run their own campaigns under pressure. With 3-Amino-5-bromo-2-fluoropyridine, technical service includes sharing reference reactions, offering insight on purification, or flagging bottlenecks seen in other industries. You get access to application notes, shared experiences, and a network that extends beyond the box itself. That personal connection becomes a lifeline. I’ve leaned on this kind of support more times than I can count—it drives efficiency and opens doors to trying bolder synthetic routes, maximizing a lab’s creativity without endless troubleshooting.
Zooming out from the beakers and spreadsheets, what 3-Amino-5-bromo-2-fluoropyridine really represents is steady progress in the way science serves society. Each successful batch, validated run, and safe shipment moves more than company profits or PI careers. It means new cancer drug candidates reach clinical trials earlier; advanced diagnostics make doctors’ jobs easier; and material scientists build solutions we barely imagined a decade ago. This compound joins a lineage of fine chemicals that, by getting the basics right—reliability, supply, purity, and technical trust—help innovation move from hope to reality.
So much of my own work has been slowed down by preventable hiccups: a contaminated lot, a missing data sheet, a supplier going silent when things get tricky. Seeing a standard-bearer rise in a crowded field cuts through the noise and turns focus back to building, refining, and discovering the next step forward. It’s more than just adding a chemical to a catalog; it’s shaping the landscape of scientific progress for the better.
Here’s how you tell value apart from hype: Tenured lab managers, procurement professionals, and risk officers look at total cost. That means factoring in product reliability, staff hours saved troubleshooting, cleanup averted, scale-up effort trimmed, and regulatory work simplified. Through that lens, a compound like 3-Amino-5-bromo-2-fluoropyridine shines brighter than flashier-sounding alternatives that deliver less in the heat of real work. Product consistency, ample documentation, supply assurance, and good old-fashioned customer support foster faith in long-term partnerships, not just transactions.
Procurement teams with years of cycles behind them know what it’s like to chase after rogue batches or wrangle with customs paperwork in the middle of critical trials. A chemical that checks the right boxes and arrives with predictable results isn’t just a convenience—it becomes a key pillar in keeping programs on pace and budgets under control. Having navigated these waters myself, I know the premium suppliers place on earnest communication and upfront problem-solving, not just price points and fancy catalogs.
So much of chemical supply is about more than molecules. Real solutions come from engaging with the field, adapting to better synthetic routes, and meeting customer needs before problems turn into lost grants, missed milestones, or abandoned discoveries. With 3-Amino-5-bromo-2-fluoropyridine, the clear path forward involves maintaining robust supply chains, doubling down on sustainable synthesis, listening to feedback from the bench, and integrating smarter support with technical documentation. Continual investment in quality control and process efficiency naturally pays dividends in efficiency and safety. After years of experience watching industries pivot and adapt, it’s clear that the suppliers making this kind of commitment shape the future.
If there’s a bottom line in choosing specialty chemicals, it’s about the value added between bottle and breakthrough. I’ve encountered countless compounds promising the world and coming up short when timelines slip or documentation wobbles. Here’s a molecule that consistently delivers—easing the technical journey from R&D curiosity to commercial reality. Scientists in search of reliability, support, and forward-thinking production processes find their expectations matched by what 3-Amino-5-bromo-2-fluoropyridine brings to the table. In a world where chemistry remains both an art and a science, that’s the kind of partner worth relying on.