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HS Code |
443541 |
| Product Name | 3,6-Dichloro Pyridine |
| Cas Number | 583-65-1 |
| Molecular Formula | C5H3Cl2N |
| Molecular Weight | 148.99 g/mol |
| Appearance | White to light yellow crystalline powder |
| Melting Point | 49-52 °C |
| Boiling Point | 210-212 °C |
| Density | 1.38 g/cm³ |
| Purity | Typically ≥98% |
| Solubility | Slightly soluble in water, soluble in organic solvents |
| Flash Point | 97 °C |
| Refractive Index | 1.567 |
| Storage Conditions | Store in a cool, dry place, tightly closed |
As an accredited 3,6-Dichloro Pyridine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 3,6-Dichloro Pyridine is supplied in a 250g amber glass bottle with a tamper-evident cap and clear hazard labeling. |
| Container Loading (20′ FCL) | Container Loading (20′ FCL) for 3,6-Dichloro Pyridine: Approximately 12 metric tons packed in 200kg HDPE drums, securely loaded for safe transport. |
| Shipping | **3,6-Dichloro Pyridine** is shipped in tightly sealed, chemical-resistant containers to prevent leaks and contamination. The packaging complies with international transport regulations, and the chemical is clearly labeled as hazardous. During transit, it should be kept away from incompatible substances, heat, and direct sunlight, with appropriate safety documentation accompanying the shipment. |
| Storage | Store 3,6-dichloropyridine in a tightly sealed container in a cool, dry, well-ventilated area away from direct sunlight, sources of ignition, and incompatible materials such as strong oxidizing agents. Use appropriate chemical-resistant containers and maintain proper labeling. Protect from moisture and prevent physical damage. Ensure access to safety equipment such as eyewash stations and maintain proper spill containment procedures. |
| Shelf Life | **3,6-Dichloro Pyridine** typically has a shelf life of 2-3 years when stored in a cool, dry, tightly sealed container. |
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Purity 99%: 3,6-Dichloro Pyridine with Purity 99% is used in pharmaceutical intermediate synthesis, where it ensures high-yield and low impurity final products. Melting Point 61°C: 3,6-Dichloro Pyridine with Melting Point 61°C is utilized in chemical process development, where it allows reliable thermal processing without decomposition. Molecular Weight 162.00 g/mol: 3,6-Dichloro Pyridine of Molecular Weight 162.00 g/mol is used in agrochemical formulation, where it provides precise stoichiometric control in active ingredient design. Stability Temperature 120°C: 3,6-Dichloro Pyridine with Stability Temperature 120°C is employed in high-temperature synthesis, where it maintains chemical integrity under reaction conditions. Moisture Content <0.5%: 3,6-Dichloro Pyridine with Moisture Content below 0.5% is used in catalyst preparation, where low water content prevents unwanted side reactions. Particle Size <100 μm: 3,6-Dichloro Pyridine with Particle Size below 100 microns is applied in fine chemical manufacturing, where homogenous mixing and rapid dissolution are critical. Appearance White Crystalline Powder: 3,6-Dichloro Pyridine as a White Crystalline Powder is chosen for solid dosage drug formulation, where consistent physical form ensures uniformity in product blends. |
Competitive 3,6-Dichloro Pyridine prices that fit your budget—flexible terms and customized quotes for every order.
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Chemists rarely agree on everything, but ask folks in the lab about reliable building blocks, and 3,6-Dichloro Pyridine usually makes the list. With a simple molecular formula of C5H3Cl2N, this compound stands tall in the pyridine family for a reason. Through years of blending tradition with advancement, I’ve leaned on it for the tough challenges that come with complex synthesis projects. Its dual chlorine substitution, right at the 3 and 6 positions, not only changes reactivity—it shapes possibility.
It’s easy to say two chlorine atoms don’t make much difference, but here, they really do. In many cases, chemical structure decides everything about a reaction—yield, purity, speed, even the hassle involved in purification later on. In the real world of R&D or manufacturing, that means more consistent results and fewer costly surprises. Finding bumps in the road halfway through a multi-step synthesis doesn’t help anyone, so this structural predictability matters.
3,6-Dichloro Pyridine handles itself differently compared with its relatives, such as 2,6-Dichloro Pyridine or mono-chlorinated pyridines. Chlorine atoms at the 3 and 6 spots shape its electron density in a way that’s tough to duplicate. This helps avoid unwanted side reactions, especially when making intermediates for pharmaceuticals or crop protection agents. Personally, I’ve found my product yields and purities stay higher and headache rates lower, especially when scaling up.
Despite the fancy chemical name, its real-world uses feel down to earth for anyone who's spent time at the bench. Many rely on it to create key intermediates for medicines, agricultural treatments, and specialty chemicals. It’s often the starting gate for reactions that will eventually build everything from cancer treatment ingredients to advanced materials for electronics.
If you picture a pharmaceutical chemist staring at a whiteboard, mapping out a new molecule, there’s a good chance they’re counting on selective transformations—stick a group here, swap a bond there—all of which depend on manageable, reproducible starting points. 3,6-Dichloro Pyridine’s clean substitution pattern makes it ideal for these “let’s make a new medicine” stories. For crop science, the same principle applies, since pyridine rings anchor so many modern herbicides and pesticides. The fact that this compound resists overreacting or breaking apart during tough chemistry means fewer failed batches, and that can translate to thousands, sometimes millions, in savings for large-scale operations.
Those who’ve ordered a bottle of this compound know it usually comes as a colorless or slightly yellowish liquid, but purity levels matter as much as appearance. Quality checks for water content and byproduct levels keep surprises low in the lab. I check for purity above 98 percent for critical synthesis work, and higher still for pharmaceutical applications. Impurities, even in small amounts, can tangle a reaction and throw off reliability. The compound’s moderate boiling point helps when distillation plays a role in purification, adding an extra layer of control.
In my experience, proper handling makes all the difference. 3,6-Dichloro Pyridine can irritate skin or eyes, so protective gear isn’t just for show here—it’s common sense. Containers must close tightly to keep the material from picking up water vapor, which not only affects purity but can slowly affect reactivity and shelf life. Used straightforwardly, though, and stored in a cool, dry area, it behaves well over months or even years.
Every year brings new pyridine derivatives and related compounds to the market, each promising better performance. Still, many chemists stick with 3,6-Dichloro Pyridine for projects where reliability matters more than chasing new trends. Some alternatives, like 2,3,5,6-tetrachloropyridine, tempt with altered reactivity, but often introduce more complexity in downstream chemistry or waste management. Others might offer better solubility or lower cost, but that only helps if the starting material actually cooperates with the sequence you’re designing.
In the push-pull between innovation and proven results, I skew toward stability, especially when every experiment means thousands of dollars and days of work on the line. My teams have compared several chloropyridines side by side. We’ve seen faster reactions with heavily substituted rings but run into more difficult purifications or inconsistent performance batch to batch. The straightforward, predictable pattern of 3,6-Dichloro Pyridine outperforms fancier chemistry in many pharmaceutical and agrochemical applications, especially at scale. For research projects, time saved on troubleshooting—reactions that go as planned, not off in unexpected directions—frequently justifies sticking with this compound.
Academic curiosity often rewards novelty, but in industry, consistency is king. Strict regulations for drug and food safety mean that even small impurities can shut down a process or, in worst-case scenarios, trigger recalls. That’s one reason why the top suppliers of 3,6-Dichloro Pyridine invest so much in tight production standards and batch testing. I’ve walked factory floors in Asia, Europe, and North America where managers monitor chromatograms as closely as sales numbers.
Achieving repeatable, scalable results comes from more than just knowing the formula. Actual labs need reagents that act the same way, every time. Variability in starting materials ripples all the way through a supply chain. It’s not just about passing one batch of quality control. Trust in 3,6-Dichloro Pyridine builds from watching hundreds of successful syntheses, knowing that what comes in the bottle today will deliver the same results tomorrow.
As with most chlorinated organics, proper environmental management matters—a lot. No one enjoys dealing with hazardous waste protocols, but byproduct disposal and emissions control shape every decision around production and use. My time as an EH&S coordinator taught me that even efficient processes need oversight, from air vent scrubbers in large manufacturing plants, to ensuring that lab-scale waste doesn’t slip into public water systems.
Dealing with toxic or persistent chemicals puts extra pressure on everyone handling 3,6-Dichloro Pyridine. Manufacturers that gather and recycle solvent waste, rather than dumping or incinerating it, draw my respect. Green chemistry isn’t just a buzzword; it offers concrete savings and safety. Encouraging suppliers to improve their own downstream handling, and checking third-party audit trails, helps keep environmental promises from becoming hollow PR claims.
Personal protective equipment and well-written standard operating procedures go further than a warning label on a drum. In the labs I’ve managed, training new staff to respect both chemical risk and process details prevents accidents and keeps compliance officers satisfied during their regular visits. The compound’s reactivity means it often works under milder conditions than older reagents, cutting down on energy demand and the amount of hazardous waste generated at each step.
As much as the headlines are about new cancer drugs or next-generation herbicides, the bread-and-butter of discovery depends on what starting materials can do. 3,6-Dichloro Pyridine shines as a flexible option; its routine use across different industries reflects broad practicality. In my experience with collaborative chemistry teams, one day might bring a pharmaceutical team looking to make new CNS-active molecules, the next, an agrochemical group aiming for selective weed control. Both lean on this compound for easy substitution, creating space to experiment without constant setbacks.
Academic research benefits, too. Students and postdocs who learn solid technique with classic reagents like this gain an intuitive sense of reactivity that translates to more complex work. The compound’s dependable performance helps educators focus on teaching deeper ideas, not just troubleshooting stubborn reactions. Across oceans and disciplines, from inexpensive generic drugs to luxury consumer products, the subtle balance of reactivity and stability marks 3,6-Dichloro Pyridine as a reliable toolkit staple.
For companies wanting shorter time-to-market cycles, the lower risk of synthetic choke points has real value. Their development chemists know how much time gets lost troubleshooting unexpected impurities or cross-reactions. Faster routes to active ingredients or specialty compounds mean quicker market launches. For smaller startups, limited budgets and tighter timelines leave little space for the gamble of more temperamental intermediates.
Global demand for pharmaceutical and agrochemical intermediates keeps the supply chains for these compounds under pressure. Every few years, changes in export controls or raw material shortages can cause hiccups. My own labs have experienced delays tied to bottlenecks in transporting hazardous precursors, or tight customs rules in countries with heavy restrictions on chlorinated compounds. Building reliable supplier networks, with backup plans and alternate sourcing, often spells the difference between a missed deadline and a smooth delivery.
Spot shortages also highlight the importance of transparency over batch data and third-party verification. More customers demand to know about every aspect of compound sourcing, from starting material origin to final transport routes. Reliable suppliers willing to share this information deliver a level of reassurance that every reaction begins with the right product. Businesses launching high-value patented products sometimes engage their own auditors, working closely with chemical vendors to reduce risk and ensure that future scaleups stay as smooth as R&D-scale tests.
Research teams interested in more sustainable pathways push for greener starting materials, especially for large-scale applications. While 3,6-Dichloro Pyridine remains favored for reliability, greener synthesis using catalytic processes—avoiding harsh reagents—shows signs of progress. Some efforts turn to bio-derived feedstocks, or to computer-guided optimization that designs new routes with fewer steps and less waste. I’ve seen incremental gains from process tweaks, like using advanced filtration and improved solvent recovery, but most new alternatives still face challenges matching the price and reproducibility of current production.
Chemists are a practical bunch, often balancing ideals with daily pressures. Even those pursuing green chemistry face tough choices—does a seemingly “sustainable” route really help if it drops yields, increases cost, or leads to new safety questions? Reviewing lifecycle analyses, rather than just upfront “green” claims, steers decisions in the right direction. I encourage teams to collaborate not only with suppliers, but also with academic researchers and regulatory experts. Honest conversations, shared data, and willingness to adjust methods can bring bolder improvements. Over time, building on sound science and reliable peer-reviewed advances moves the whole field ahead.
In practical chemistry, the real work comes down to what a material can do where it matters most—in the lab, the plant floor, the manufacturing suite. 3,6-Dichloro Pyridine, despite a history that feels almost mundane, sets a standard through performance, reliability, and flexibility that new candidates struggle to outdo. Users with years of hands-on experience still value proven results over marketing claims and untested alternatives.
The future for specialty chemicals lies in balancing consistency, safety, sustainability, and cost. Whether you’re working in global pharmaceuticals or local research labs, making these choices thoughtfully means progress won’t stall. The next breakthrough may use fancier, more sustainable intermediates. For now, trusted tools like 3,6-Dichloro Pyridine keep discoveries moving forward—one thoughtful reaction at a time.