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HS Code |
103875 |
| Name | 2-Pyridinecarboxaldehyde, 6-fluoro |
| Synonyms | 6-Fluoropicolinaldehyde |
| Cas Number | 349-10-8 |
| Molecular Formula | C6H4FNO |
| Molecular Weight | 125.10 |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 208-209 °C |
| Density | 1.251 g/cm3 |
| Purity | Typically ≥ 97% |
| Smiles | C1=CC(=NC(=C1)F)C=O |
| Inchi | InChI=1S/C6H4FNO/c7-5-1-2-6(4-9)8-3-5/h1-4H |
| Flash Point | 88.2 °C |
| Storage Temperature | 2-8 °C |
| Solubility | Soluble in organic solvents |
As an accredited 2-Pyridinecarboxaldehyde,6-fluoro factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle, 25 grams, screw cap with tamper-evident seal, GHS hazard labels, chemical name and CAS number clearly displayed. |
| Container Loading (20′ FCL) | Container Loading (20′ FCL) for 2-Pyridinecarboxaldehyde,6-fluoro involves secure, sealed drum packing to prevent spillage and ensure safe transit. |
| Shipping | 2-Pyridinecarboxaldehyde, 6-fluoro is shipped in tightly sealed containers, protected from moisture and light. It is classified as a hazardous chemical, requiring appropriate labeling and adherence to safety regulations during transport. Certified carriers handle the shipment, ensuring compliance with relevant local, national, and international shipping standards for hazardous substances. |
| Storage | 2-Pyridinecarboxaldehyde, 6-fluoro should be stored in a cool, dry, well-ventilated area, away from incompatible materials such as strong oxidizing agents and acids. Keep the container tightly closed when not in use. Store at room temperature, and protect from moisture and light. Ensure proper labeling, and follow all relevant safety protocols for handling hazardous chemicals. |
| Shelf Life | 2-Pyridinecarboxaldehyde, 6-fluoro should be stored tightly sealed, protected from light and moisture; typical shelf life is 2–3 years. |
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Purity 98%: 2-Pyridinecarboxaldehyde,6-fluoro with a purity of 98% is used in pharmaceutical intermediate synthesis, where it ensures high yield and product consistency. Melting point 48°C: 2-Pyridinecarboxaldehyde,6-fluoro with a melting point of 48°C is used in organic reaction setups, where it allows for easy handling and precise dosing. Molecular weight 139.11 g/mol: 2-Pyridinecarboxaldehyde,6-fluoro with a molecular weight of 139.11 g/mol is used in N-heterocyclic ligand preparation, where it contributes to accurate molar calculations and stoichiometry. Stability temperature up to 60°C: 2-Pyridinecarboxaldehyde,6-fluoro stable up to 60°C is used in high-temperature coupling reactions, where it maintains structural integrity during synthesis. Particle size <100 μm: 2-Pyridinecarboxaldehyde,6-fluoro with a particle size less than 100 μm is used in solid-phase synthesis protocols, where it enables efficient mixing and reaction rates. Water content <0.5%: 2-Pyridinecarboxaldehyde,6-fluoro with water content under 0.5% is used in moisture-sensitive chemical manufacturing, where it prevents side reactions and degradation. UV absorbance: 2-Pyridinecarboxaldehyde,6-fluoro exhibiting strong UV absorbance is used in analytical method development, where it enhances detection accuracy in HPLC analysis. |
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Building chemicals isn't a mysterious process filled with jargon and secrecy. In our plant, we're hands-on every day, handling real molecules for real-world demands. Among our lineup, 2-Pyridinecarboxaldehyde,6-fluoro stands out because customers come knocking for a reason: its core structure unlocks chemical reactions other products simply don’t manage as efficiently. Every bottle leaving our loading docks carries the results of our experience, testing, and attention to detail.
What makes 2-Pyridinecarboxaldehyde,6-fluoro so useful? Its chemical backbone—pyridine with a 6-fluoro substitution and an aldehyde group—creates reactivity not found in many common building blocks. The fluorine doesn't just sit there; it shifts electron density, impacting both chemical reactivity and downstream behavior in synthesis routes. Instead of just adding complication, that small change creates opportunities, letting chemists build things like specialty pharmaceuticals, fine chemicals, and crop protection agents with high purity yields.
The aldehyde function on the pyridine ring serves as both a site for reaction and as a handle for more complex transformations. In our production batches, the difference between a pure, predictable 2-Pyridinecarboxaldehyde,6-fluoro and lesser versions is seen in the bottom line—yields go up, downstream separations get simpler, by-products decrease, and waste streams become easier to treat. On the ground, it cuts costs and saves troubleshooting time.
Our manufacturing team doesn’t use an off-the-shelf recipe. Years of pilot work taught us how this compound likes to behave. Getting the substitution pattern correct—always with the functional groups in the right orientation—takes consistent conditions, close monitoring, and raw materials we trust. It’s a highly controlled process, not just shuffling reactants together and hoping for the best.
In the lab, we looked at dozens of possible routes, tracked side reactions, and rejected more than a few approaches that seemed good on paper but didn’t deliver the purity or scale real-world formulators demand. Today, our batches run under continuous monitoring with in-process checks at every stage. We keep residual moisture low, manage side products, and test for trace impurities. Our chemists handle each lot with deliberate adjustments to temperature, solvent quality, and reaction timing. Every process tweak was driven by direct customer feedback: problems seen in their plants, not just ours.
We see 2-Pyridinecarboxaldehyde,6-fluoro pulled most often by labs and companies working on modern pharmaceutical scaffolds. Its aldehyde group lets medicinal chemists form imines, oximes, and other derivatives with less risk of overreaction or clutter from unwanted side reactions. The 6-fluoro modification changes binding in biological tests. In crop science, our customers are building innovative active ingredients that need subtle shifts in electron balance. This molecule’s structure gets them there faster, with fewer iterative steps.
Early on, a group working on CNS drugs in custom synthesis ran into dead-ends when using unsubstituted or methyl-substituted analogues. Yields were low, isomer ratios unpredictable, and purification was tedious. Switching to our 6-fluoro variant streamlined their process. Final products came out cleaner, and pilot batches scaled smoothly. That result didn’t just come from theoretical chemistry; it came from reproducibility in the bottle. We’ve seen similar stories from agrochemical formulating partners, whose final formulations gain improved shelf life thanks to the enhanced stability of intermediates built from this base.
We don’t treat each specialty chemical as just another item code. For each product, including 2-Pyridinecarboxaldehyde,6-fluoro, every batch is backed by our in-house QA routines tracing all the way back to raw material sourcing. We don’t subcontract out the key steps that determine quality. If there’s ever a hiccup, our technical support team is the same crew who run the reactors and troubleshoot every step. On a personal level, nothing is left to chance—each shift hands off tight records, and everything is double-checked, from raw material intake to packaging.
The product leaves our plant in clear, secure packaging, labeled every step of the way. We know customers have specification sheets in hand, but from our side, it’s the unseen details that matter. Each batch synthesis gets traced, with analytical work that covers not only purity and composition but also parameters like volatility, trace metals, and water content. We even keep retention samples for post-delivery peace of mind. That hands-on approach means, if a question arises a month—or a year—later, we have honest, detailed records to go back to. Our pride comes from personal oversight, not just meeting paperwork minimums.
You’ll find pyridinecarboxaldehydes in most chemical supplier catalogs, but adding the 6-fluoro group is more complicated. The differences show up in the nitty-gritty of synthetic work. Many customers have worked with unsubstituted 2-pyridinecarboxaldehyde or those with methyl, chloro, or nitro substitutions. Each brings a new reactivity profile, but the 6-fluoro variant nudges electronic effects in a direction that’s tough to mimic artificially. Side reactions common with other substitutions drop off. Final products show better selectivity on chromatography. We’ve seen how the spectral fingerprint of our product lets analytical chemists spot it among impurities, which saves analytical time and cuts lost batches.
Another concrete difference: storage and handling. With some analogs, especially those with bulkier or more reactive substituents, instability means shorter shelf lives, more degradation on storage, or more hazardous side-products. Through years of shelf testing in both our plant storerooms and at customer sites, we’ve tracked container compatibility and product longevity. The 6-fluoro compound resists breakdown, minimizes container leaching, and maintains reactivity without building up unwanted by-products.
Down the line, those who purchase our product aren’t just checking in for paperwork. They rely on real, batch-to-batch consistency for scale-up and regulatory submission. Losing a batch to variability means time, money, and—on tight development timelines—lost opportunities. We’ve seen companies forced to start over when they try switching sources, but those who stick with our product rarely double back to troubleshoot batch surprises. That consistency stems from simple factors: careful plant management, operator experience, robust maintenance, and a refusal to compromise on raw material selection. If a supplier’s lot seems “off,” we reject and re-source rather than passing a headache downstream.
Another day-to-day challenge? Shipping schedules. Chemical manufacturing can grind to a halt when specialty intermediates are stuck in customs, delayed by paperwork, or subject to unplanned audits because of regulatory ambiguities. Over the years, we’ve built in reliable contingency planning. Stocking policies, document tracking, and communication with logistics partners got honed from hard lessons. Our clients benefit from that predictability: with a dependable pipeline, they can schedule their own runs with confidence.
Talking about “regulatory compliance” only makes sense if it’s integrated into production, not just an afterthought for the compliance office. Our plant’s control systems track each raw material, reaction parameter, and analytic result. Waste handling doesn’t stay theoretical—we devote real effort to minimizing solvent emissions and processing by-products efficiently. Because 2-Pyridinecarboxaldehyde,6-fluoro often lands in late-stage synthesis just before formulation or active ingredient finalization, there’s no room for cross-contamination or mislabeling.
Traceability comes down to more than batch numbers and signed-off release forms. Each unit can be tracked back to individual shifts and specific operators. We’ve invested in both digital and hard-copy backup systems: even in a network outage, there’s always a paper trail. Over the long haul, product recalls, customer audits, and market stewardship all flow smoothly because these protocols aren’t bolted on—they’re woven into our culture. From our perspective, environmental stewardship isn’t a forced checkbox, but a survival requirement: our operators live in the same communities our plant serves, and real spills or hazardous emissions aren’t just hypothetical problems. Investing in safe equipment, local containment, and responsible disposal makes good business sense and keeps everyone safe.
A new batch of 2-Pyridinecarboxaldehyde,6-fluoro moves straight from our reactors to downstream testing. Before that first shipment, we test it in a handful of prototype reactions, both in our lab and with trusted synthesis partners. Our team evaluates not just purity, but how easily it dissolves, reacts, and isolates in the most common synthetic pathways. We’ve run side-by-side comparisons with other available sources, flagging not only minor impurity peaks, but also subtle differences in reactivity and color stability. Where off-brand products failed or required endless tweaking, our batches ran cleaner every time.
These lessons mattered most for customers who run automated synthesis lines. Robots don’t forgive batch drift or changing impurity profiles. More than one pharmaceutical group shared stories of entire libraries built faster once they landed reliable 2-Pyridinecarboxaldehyde,6-fluoro. We take pride in being the logical choice for streamlining automation—the workhorse feedstock that makes high-throughput development possible.
What we've learned comes straight from the field. Users talk to our support chemists about filtration times, residue build-up, or subtle delays in reaction runs. Our process engineers review these reports and send valuable feedback all the way back to batch design. Our plant always looks for ways to tweak operating conditions, fine-tuning temperature ramps, mixing speeds, and reagent ratios. Even seemingly minor changes, such as the purity of a key precursor, can drive down process costs or boost product shelf life.
Open communication sets us apart. New requests for specialty purities or tightly specified impurity profiles prompt experiments in our pilot plant, not just apologies or excuses. Creative problem-solving forms the core of our approach, and our product keeps evolving based on real feedback—not just top-down management decrees or abstract sales pitches.
Nothing about producing fine chemicals allows shortcuts. Building a reliable supply of 2-Pyridinecarboxaldehyde,6-fluoro demanded years of know-how, hands-on innovation, and commitment to quality that never wavers. Our real-world approach rewards users: less troubleshooting, consistent output, and smooth integration with downstream processes. Those benefits aren’t just luck—they reflect an entire company’s effort, from the receiving dock to the technical desk.
Each day, users count on us to do more than fill an order—they expect honest support and genuine technical partnership. We put our experience into every batch, knowing full well that reputation, safety, and innovation all grow together. For anyone seeking more than a basic supply, 2-Pyridinecarboxaldehyde,6-fluoro exemplifies what dedicated manufacturing brings to the table: reliability, performance, and a relentless push to do the job right.