2-PYRIDINECARBONITRILE, 3,5-Dichloro-

    • Product Name: 2-PYRIDINECARBONITRILE, 3,5-Dichloro-
    • Chemical Name (IUPAC): 3,5-dichloropyridine-2-carbonitrile
    • CAS No.: 40046-26-6
    • Chemical Formula: C6H2Cl2N2
    • Form/Physical State: Powder Solid
    • Factroy Site: No.968 Jiangshan Rd., Nantong ETDZ, Jiangsu, China
    • Price Inquiry: sales7@boxa-chem.com
    • Manufacturer: Nantong Acetic Acid Chemical Co., Ltd.
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    Specifications

    HS Code

    542494

    Chemical Name 2-Pyridinecarbonitrile, 3,5-dichloro-
    Molecular Formula C6H2Cl2N2
    Molecular Weight 173.00
    Cas Number 884494-18-4
    Appearance Pale yellow to light brown crystalline powder
    Melting Point 93-98°C
    Purity Typically ≥98%
    Solubility Slightly soluble in water, soluble in organic solvents
    Smiles N#Cc1ncccc1(Cl)Cl
    Inchi InChI=1S/C6H2Cl2N2/c7-4-1-5(8)10-6(2-4)3-9
    Storage Conditions Store in a cool, dry place, tightly closed
    Synonyms 3,5-Dichloro-2-cyanopyridine

    As an accredited 2-PYRIDINECARBONITRILE, 3,5-Dichloro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The chemical comes in a sealed, amber glass bottle containing 25 grams, featuring a hazard label and clearly marked compound identification information.
    Container Loading (20′ FCL) Container Loading (20′ FCL) for 2-PYRIDINECARBONITRILE, 3,5-Dichloro-: Packed securely in drums or bags, maximizing space efficiency and safety.
    Shipping **Shipping Description for 2-PYRIDINECARBONITRILE, 3,5-Dichloro-:** Ships as a hazardous chemical, typically in tightly sealed containers to prevent moisture or air exposure. Requires clear labeling, proper documentation (SDS included), and packaging compliant with local, national, and international regulations. Handle with gloves and eye protection. Transport under ambient temperature unless specified otherwise. Avoid direct sunlight and physical damage during transit.
    Storage Store **3,5-dichloro-2-pyridinecarbonitrile** in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible materials such as strong acids or bases. Keep the container tightly closed and properly labeled. Protect from moisture and direct sunlight. Use secondary containment to prevent spills, and ensure storage complies with local chemical safety regulations.
    Shelf Life The shelf life of 2-Pyridinecarbonitrile, 3,5-dichloro- is typically 2-3 years when stored in a cool, dry place.
    Application of 2-PYRIDINECARBONITRILE, 3,5-Dichloro-

    Purity 98%: 2-PYRIDINECARBONITRILE, 3,5-Dichloro- with purity 98% is used in pharmaceutical intermediate synthesis, where it ensures high yield and product purity.

    Melting Point 97°C: 2-PYRIDINECARBONITRILE, 3,5-Dichloro- with a melting point of 97°C is used in solid-state organic synthesis, where it provides thermal stability during reactions.

    Molecular Weight 172.02 g/mol: 2-PYRIDINECARBONITRILE, 3,5-Dichloro- with molecular weight 172.02 g/mol is used in agrochemical research, where it facilitates accurate formulation and dosing.

    Stability Temperature 25°C: 2-PYRIDINECARBONITRILE, 3,5-Dichloro- with a stability temperature of 25°C is used in ambient storage facilities, where it minimizes degradation and preserves reactivity.

    Particle Size <50 µm: 2-PYRIDINECARBONITRILE, 3,5-Dichloro- with particle size less than 50 µm is used in fine chemical synthesis, where it enhances dispersion and reaction kinetics.

    Reactivity Profile – Nitrile Group: 2-PYRIDINECARBONITRILE, 3,5-Dichloro- with a reactive nitrile group is used in advanced heterocycle construction, where it enables efficient functional group transformations.

    Low Water Content: 2-PYRIDINECARBONITRILE, 3,5-Dichloro- with low water content is used in moisture-sensitive catalysis, where it prevents undesired hydrolysis and maintains catalyst activity.

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    Certification & Compliance
    More Introduction

    2-PYRIDINECARBONITRILE, 3,5-Dichloro-: Experience and Perspective from the Manufacturer

    Understanding 2-PYRIDINECARBONITRILE, 3,5-Dichloro- in Real Practice

    Surrounded by glassware, technical drawings, and stacks of lab notes, we work with 2-PYRIDINECARBONITRILE, 3,5-Dichloro- every day. This fine crystalline compound comes out of our reactors with consistency and a pale off-white or faintly grey color that tells us the chemistry has run right. Our team watches every batch from start to finish. With each kilo we produce, there’s a sense of responsibility, knowing how crucial it is to control every variable in such a nuanced synthesis. The world of pyridine chemistry can be demanding. Out there, plenty of products vie for the chemist’s attention, but not all reach the level of purity and physical character we have stabilized through years of incremental tweaks. Now, end users count on a reliable batch that blends into their process without much trouble. They look for free-flowing powder, with low moisture and residue. We understand these needs because we’ve stood in their shoes and heard their feedback directly.

    Our Approach to Crafting Each Batch

    Here, you won’t find automated shortcuts or cost-driven substitutions that compromise the product’s critical properties. Every process stage—right from weighing out raw materials through to final drying—is handled by people who have seen what can go wrong. Moisture creeping in during rainy seasons threatens yields. Trace metal contamination lurks if equipment fails basic checks. We’ve developed routines for batch sampling at intervals that confirm the key chemistries stay true, and we open every lot certificate to real scrutiny, not just paperwork. When the product comes out, it gets deliberately stored on-site to ensure lots stabilize before packing. By doing so, we avoid clumping and agglomerates, which would cause handling headaches at your end.

    Why Purity and Batch Integrity Truly Matter

    Open discussions with downstream formulators led us to a simple truth: even a few tenths of a percent in impurity can obstruct yields or introduce regulatory review headaches. The 2-PYRIDINECARBONITRILE, 3,5-Dichloro- we offer stays within tight specifications. Typical assays reach above 99.5% by HPLC, and by keeping residual solvents far below detection, we dodge problems that might otherwise appear during critical intermediate reactions. In some larger plants, stray metals leftover from catalyst use show up late, after long reaction chains. In our case, repeated washing and careful choice of reagents nearly wipes that threat out. Every extraction gets monitored for organics and inorganics, and each staff member has hands-on knowledge of the separation process.

    Knowing actual end use cases helps keep us practical. Colleagues have shared stories about difficult filtrations or poorly crystalline off-grade from other sources, which wastes resources. We avoid unnecessary dust or a product that doesn’t wet properly, because those little details add hours to a production timeline. Agglomerates, uneven crystal sizing, and moisture spikes can spell real downtime. So we focus on a consistent particle size distribution and manage drying until nothing sticks or cakes. We always set aside a sample from each lot, so if issues come up six or twelve months later, we have traceability, and you can show that to auditors with confidence.

    Supporting Complex Synthesis—Our Product at the Core of Value Chains

    2-PYRIDINECARBONITRILE, 3,5-Dichloro- sits up front in many demanding synthesis routes. It has become a preferred choice as a building block in specialty and pharma sectors because of its dual chloro functionality and the reactivity profile that comes from the nitrile group. Several major agrochemical actives rely on this molecule as an early intermediate, where a stable, reproducible scaffold is crucial. Because we produce at scale, our supply helps anchor these value chains against sudden changes in quality or availability, which can ripple through downstream plants.

    In pharma, timing is everything. If crystallization behaves unpredictably or if trace amounts of side products drift into the batch, the time and cost to troubleshoot grows out of hand. Over the years, we’ve been approached to troubleshoot stuck reactions and filtration failures that clear up only after switching to a cleaner, tighter grade. The certainty in our process creates the breathing space for chemists to do their work with confidence.

    Differentiating from Other Pyridine Derivatives

    Chemically, 2-PYRIDINECARBONITRILE, 3,5-Dichloro- distinguishes itself not just by its substituents, but in function. Many competitors in the pyridine market produce generic nitriles or mono-chloro versions with a similar name but quite different behaviour in real-world applications. During cross-coupling or halogen exchange chemistry, the difference shows up immediately. Dual chlorination at the 3 and 5 positions tunes the molecule’s reactivity—halogen exchange progresses at a controlled pace, allowing for predictable yields and minimal byproducts. Mono-chloro variations show wider batch-to-batch outcome swings, with some process runs generating more colored or greasy residues.

    Trying to substitute with a generic pyridinecarbonitrile almost always costs more in process correction than any upfront savings. The shelf stability, solubility profile, and integration into automated dosing setups also differ. Our product delivers a level of stability under storage conditions that results from years spent tweaking drying and handling methods. In contrast, off-brand imports can arrive with moisture-loading, fine dust, or color shifts that betray poor handling or rapid, bulk synthesis that skips intermediate quality checks.

    Meeting Regulatory and Safety Expectations

    Being a direct manufacturer, not a trader, exposes us to all the documentation and due diligence from regulatory authorities. We run documentation audits and pre-delivery checks in response to REACH and other relevant frameworks. Risk assessments are performed with practical knowledge—understanding that minute phosphorus levels, trace metals, or unanticipated degradation products can trigger recalls or extra registrations for our customers. Our safety and environmental management systems grew out of decades of operating under real world constraints, not from one-size-fits-all handbooks.

    Long-term storage tests showed us that polyethylene-lined drums, sealed with tamper-proof gaskets, work best for this material. During a heatwave one year, an attempt to switch to generic bags resulted in caking and discoloration, an expensive lesson in material compatibility. We started logging ambient warehouse humidity and tracking delivery temperature history as part of our quality assurance, so every shipment carries a record of the conditions it endured. This level of traceability matters in regulated sectors; it also lets us stand behind our product during audits.

    Usage Realities—In the Lab and on the Plant Floor

    2-PYRIDINECARBONITRILE, 3,5-Dichloro- steps into a range of intermediate chemistries—Suzuki couplings, nucleophilic substitutions, or as a platform for complex ring assemblies. Working directly with process engineers, we realized subtle differences in solubility or powder behavior change mixing speeds and solvent loadings. We keep an open line to technical teams at end users' plants to discuss such matters, improving not only our own workflow but theirs too.

    Chemists often push for product that dissolves quick, disperses without forming stubborn clumps, and resists static. We learned that granulation and careful sieving favor smooth batch charging, so we implemented dedicated steps instead of sending all material through a single universal mill. Consistency pays back: during automated dosing, the avoided blockages and dust buildup translate directly to fewer maintenance checks and downtimes, something operators appreciate far more than any statistics from the lab.

    Continuous Improvement Guided by Hands-On Feedback

    Over the years, not every batch met our ambitions. Early runs sometimes reached spec but felt “off”—too musty, tendencies to yellow, or just hard to weigh out quickly. Feedback from users pushed us toward new purification steps. An off-odour batch prompted a closer look at trace amines, which we traced to a vendor shift in an upstream reagent. Some attempts to save energy during drying led to stubborn humidity issues in some drums, so we adapted our drying curves and lengthened vacuum drying time.

    By seeing our customers’ production floors firsthand, we realized the impact of even small changes in our internal standards. A small tweak in crystal habit, achieved by changing stirring geometry, drastically reduced caking at several downstream facilities. Our quality team invites back direct feedback, offering custom sample runs with different sieve sizes or drying endpoints, something not often available from bulk traders. Even as regulations tighten or customers scale up, we fine-tune to keep step.

    Supply Chain Stability and Scale for Industrial Consistency

    Large-scale formulators and multinational production facilities rely on smooth and uninterrupted supply. Our operations balance capacity with inventory management. We run continuous manufacturing schedules with enough buffer to keep lead times short, even during surge periods. Seasonal demand spikes push some producers to drop standards or buy from unvetted suppliers; we keep a rolling buffer and multi-sourced precursors so our quality doesn’t slip under pressure.

    Long-term relationships built with purchasers who value repeatability helped us align logistics for global shipments. Honestly, a hard-won lesson was that shipment conditions could undo hard work upstream. A shipment crossing hot, humid climates in basic containers can undergo subtle degradation. After learning this firsthand, we made climate-sensor-logging routine and built stronger links with shipping partners to schedule at-risk routes more carefully. These are the visible signs of a producer who doesn’t pass the buck; ultimately, the end user feels the benefit in uncompromised performance and worry-free audits.

    Environment, Safety, and Employer Values

    In chemical manufacturing, reputation grows not from advertising but reliability and responsibility. Our direct oversight covers local environmental oversight; we treat our effluent ourselves and self-monitor for byproducts. Communities near production sites watch us and expect attention to detail not just in products but in how we handle wastes and emissions. That accountability carries into our everyday thinking: plant staff have a direct line to supervisors to report errors or near-misses, and retraining becomes a matter of pride, not penalty. Sometimes this draws out a batch cycle, but it prevents shortcuts.

    We avoid solvent swaps or shortcutting filtration just to shave costs if it might alter safety parameters or leave new residue. Every staff member handling this product trains directly in the plant, not just the classroom. This experience ripples through in the final product, which supports the safety claims made on paperwork. The market has grown to expect not just the right physical characteristics but the story and proof behind it.

    Working with Partners Committed to Progress

    Collaboration with others working at the frontier—those piloting novel synthetic routes, trialing new actives, or building out next-generation APIs—drives our progress. Direct discussions about required modifications to base specifications or integrating tighter controls on trace elements keep us invested and responsible. Some projects asked for ultra-low sodium or fine-tuned polymorphs; we adjust our process, knowing how much is at stake in scale-up.

    We resist trend-following for its own sake; instead, we test novel purification and granulation approaches based on actual process engineer feedback, ensuring the product never just meets but slightly exceeds expectations of performance in actual chemistry. That loop of short, direct communication builds mutual accountability, sharpens our quality, and keeps us innovating without falling prey to the unpredictability of generic market players.

    Responsiveness in a Changing Industry

    Shifts in end-market demand, changing regulatory environments, and new competitive entrants all challenge established producers to stay ahead. Our practice, built from actual failures and learned lessons, positions us to anticipate—not just react to—what end users need in a changing regulatory context. Recent years brought new scrutiny on process contaminants and evolving tolerance limits on elemental profiles. Tightening safety and transport rules led us to overhaul our packing and shipping protocols, all implemented far ahead of regulatory deadlines.

    Having staff with years of hands-on chemistry experience helps. Instead of relying solely on generic guidelines, our lab investigates new impurities proactively, controls stability and ensures that the chemistry holds up under the latest stress test scenarios. By staying active in working groups and industry consortia, we stay aware of trends and challenges impacting both chemicals manufacture and practical synthesis at scale.

    The Real Value of Transparent Practice

    Anyone can claim high purity in an online listing, but real value shows up when users call about an unexpected process result and discover direct access to our technical team. Traceability, knowledge of supply chain origin, and real people to answer each question are marks of a genuine manufacturer. We retain every lot sample for long-term reference and keep detailed batch histories. Each customer audit gets welcomed as a partnership, not an inconvenience—we learn as much from these exchanges as our clients do.

    Every challenge, from batch coloration to crystallinity, is familiar territory. Because we control each stage internally and never outsource, we correct faster and communicate openly about improvements. This honest, decade-built approach to manufacturing 2-PYRIDINECARBONITRILE, 3,5-Dichloro-, guided by real-world use cases and sustained by responsive feedback, forms the foundation for the reliability and trust clients return to year after year.

    Looking Ahead—Innovation, Reliability, and Partnership

    Our journey with this compound reflects the best lessons of chemical production: maintain hands-on vigilance, adapt with evidence, respect feedback, and innovate only as fast as the real world demands. Standing as a manufacturer at the center of this niche, we work hard to make 2-PYRIDINECARBONITRILE, 3,5-Dichloro- not just a commodity but a true enabler for those pushing the boundaries of discovery and production.

    Direct experience tells us that attention to every small detail, from warehouse humidity to documentation transparency, acts as an investment in your success and trust. We make every effort to raise the baseline for quality and service, not just for ourselves but on behalf of everybody relying on the invisible strengths of our process to carry their projects further.