|
HS Code |
522502 |
| Chemical Name | 2-Amino-5-nitropyridine |
| Cas Number | 4487-56-7 |
| Molecular Formula | C5H5N3O2 |
| Molecular Weight | 139.11 |
| Appearance | Yellow to brownish-yellow solid |
| Melting Point | 138-141°C |
| Boiling Point | 404.1°C at 760 mmHg |
| Solubility | Slightly soluble in water |
| Density | 1.49 g/cm³ |
| Purity | Typically ≥98% |
| Synonyms | 5-Nitro-2-pyridinamine |
| Smiles | NC1=NC=CC(C1)=O[N+](=O)[O-] |
| Inchi | InChI=1S/C5H5N3O2/c6-5-2-1-4(8-3-5)7(9)10/h1-3H,(H2,6,8) |
| Storage Temperature | Store at room temperature |
| Hazard Statements | Irritant to skin, eyes, and respiratory system |
As an accredited 2-Amino-5-nitropyridine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The packaging contains 100 grams of 2-Amino-5-nitropyridine, sealed in an amber glass bottle with a secure screw cap and hazard labeling. |
| Container Loading (20′ FCL) | Container Loading (20′ FCL) for 2-Amino-5-nitropyridine involves bulk packaging, secure drums or bags, maximizing space, and ensuring safe chemical transport. |
| Shipping | 2-Amino-5-nitropyridine is shipped in tightly sealed containers to prevent moisture ingress, typically using glass or HDPE bottles. It is classified as a hazardous chemical and must be packaged according to regulatory guidelines, with proper labeling and documentation. Transport follows local and international hazardous materials regulations to ensure safe delivery. |
| Storage | 2-Amino-5-nitropyridine should be stored in a tightly sealed container, in a cool, dry, well-ventilated area away from sources of ignition. Keep away from incompatible materials such as strong oxidizers and acids. Protect from direct sunlight and moisture. Recommended storage temperature is typically room temperature, but refer to the supplier’s safety data sheet (SDS) for specific storage guidelines. |
| Shelf Life | 2-Amino-5-nitropyridine has a shelf life of at least 2 years if stored in a cool, dry, tightly sealed container. |
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Purity 99%: 2-Amino-5-nitropyridine with purity 99% is used in pharmaceutical intermediate synthesis, where high purity ensures minimal impurities in final active ingredients. Melting Point 140°C: 2-Amino-5-nitropyridine with a melting point of 140°C is used in organic chemistry research, where precise thermal characteristics enhance reproducibility in compound formation. Particle Size < 50 µm: 2-Amino-5-nitropyridine with particle size below 50 µm is used in dye formulation, where fine particle distribution improves color uniformity and dispersion. Moisture Content < 0.5%: 2-Amino-5-nitropyridine with moisture content less than 0.5% is used in electronics material synthesis, where low moisture prevents unwanted side reactions. UV Absorbance (λmax 350 nm): 2-Amino-5-nitropyridine exhibiting UV absorbance at λmax 350 nm is used in photoinitiator development, where optimal absorbance enhances photoreactivity efficiency. Stability Temperature up to 60°C: 2-Amino-5-nitropyridine stable up to 60°C is used in agrochemical formulation, where high stability ensures consistent bioactivity during storage. Assay ≥ 98% (HPLC): 2-Amino-5-nitropyridine with assay ≥ 98% by HPLC is used in fine chemical manufacturing, where precise assay delivers reliable batch-to-batch consistency. |
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Some chemical compounds quietly drive industries forward, connecting laboratories, factories, and medical innovators. Among these is 2-Amino-5-nitropyridine. Known for its balanced structure, this aromatic heterocycle makes a difference in more ways than most realize. For scientists, its C5H5N3O formula means possibilities, not just numbers. Each mole brings the backbone for new molecules in dyes, pharmaceuticals, and niche chemicals.
Every scientist knows real quality sits in the details. I’ve seen researchers lean on 2-Amino-5-nitropyridine for its consistent crystalline form and the reliable nitro and amino group positions on the pyridine ring. This specific substitution lets it serve as a springboard for hundreds of chemical reactions. In pharmaceutical synthesis, it can build anti-infective agents, treat specialized diseases, and introduce new functional groups for targeted therapies. The accuracy of its melting point, its clarity on the chromatography readings, and the absence of sticky byproducts bring certainty to workflows.
Dye manufacturers appreciate how it deepens color fastness in final products. Its presence in the molecular mix gives dyes a unique stability, holding up to sunlight, sweat, and repeat washes. With high purity—often quoted upwards of 98% from trusted suppliers—formulators gain confidence for their next big experiment. Purity isn’t just a number, either. Trace impurities will ruin yields, gum up equipment, or fail regulatory checks, but a well-prepared batch of 2-Amino-5-nitropyridine won’t cause those headaches.
Crammed inside a lab for days on end, I remember how much smoother experiments ran when this compound showed up in the right form. Its stability in room conditions saves anxious midnight trips to the refrigerator. Its crystalline nature means dosing is accurate, whether weighing milligrams or layering reaction vessels. Compared to more volatile reagents, 2-Amino-5-nitropyridine survives the handling of a beginner just as well as a seasoned technician. Technicians barely complain about dustiness or the static mess that comes with lighter powders.
Batch scans through NMR, HPLC, or IR spectra tell stories about real-world performance—traces of solvents or isomeric shifts will change the results downstream. This is where having a model specification dedicated to higher standards turns burdensome reruns into confident, publishable chemistry. In teaching, students grab onto the recognizable odor, the yellow crystalline hue, and the melting point around 164–168 °C, learning to connect numbers to tactile experience. For seasoned professionals, these traits signal reliability, making planning more precise and less stressful.
Some might be curious about how this compound stacks up next to similar nitro-substituted pyridines or other aminated heterocycles. From direct experience, most alternatives either lack the flexible reactivity or prove more toxic to handle. For example, placing the nitro or amino groups in other spots on the ring changes electron flow, impacting reaction speed and selectivity. Even small changes in molecular orientation make a big difference. I once swapped in a 4-nitro-pyridine variant, and the entire reaction mix changed color, forcing hours of troubleshooting. Materials with close names don’t always do the job.
Cost figures into it, too. While high-purity specialty chemicals run up bills quick, cost per gram drops as yields improve and reactions need less clean-up. Alternative compounds sometimes show up cheaper on paper, but the post-processing costs—chromatography, purification, even waste disposal—eat away at the bottom line. For experienced buyers, value means fewer headaches, not just a lower invoice.
A quick note on handling. Lab veterans respect 2-Amino-5-nitropyridine's low volatility and relative mildness, but nothing ever replaces gloves and goggles. No one forgets a spill, even with low-toxicity powders. Water doesn’t degrade it easily, and its reactivity with acids or bases means technicians need to plan cleanup in advance. Each new user picks up protocols fast, which means fewer accidents—a clear win for both safety records and staffing budgets.
Long-term users know how pain-free storage can save money in lost inventory, especially if a compound keeps its integrity over months or years. No one enjoys scraping brown goo from old bottles: with proper storage, this compound keeps its edge, staying usable for multiple projects or remote site deliveries.
Natural curiosity leads many to ask about disposal and environmental impact. From my work with waste officers and compliance inspectors, 2-Amino-5-nitropyridine holds a middle ground; it doesn’t leach quickly or cause major ecological headaches, but any lab running production-scale work sorts out collection and treatment with care. Solubility profiles distribute it evenly in solvents, so managing rinse-outs and filtration means pulling together the right team and having standard procedures.
I’ve seen older colleagues chase after green chemistry principles, swapping to this compound for more targeted synthesis with fewer byproducts. Switching to more selective reagents does more than just cut emissions—it drives a culture of responsibility through the whole organization. Tools like dedicated waste streams and solvent recycling take a little extra time, but they meet consumer pressure for lower-impact production and industry regulations on chemical discharge.
In practice, the difference between working with a trusted batch and an unknown one makes or breaks a research project. Anyone serious about consistent results keeps strong relationships with reliable vendors, monitoring lots via certificates of analysis and in-house double-checks. From personal connections with purchasing teams, stories circulate about rogue batches that turned out yellowish-brown, sparking urgent calls for reshipments and re-qualification. Having a dependable supply saves time, money, and—most of all—the morale of every scientist in the chain.
Modern regulatory compliance pushes suppliers to share extended info about sourcing, content, and contaminant levels. This goes beyond ticking boxes for audits. Every detail, from label to last gram, shapes an operation’s reputation. When final product inspections run smooth, no one grumbles about paperwork—a sure sign of a chemical that delivers more than just molecular function.
As industries chase ever-higher yields and greener workflows, standard compounds like 2-Amino-5-nitropyridine prove how thoughtful molecular design drives improvement across sectors. Each step in a research chain introduces fresh variables, yet using proven intermediates means fewer unknowns. Years ago, I watched how a single switch in reagents led to an uptick in failed batches. That hard-won lesson underscored the need for reliability and consistency—the same strengths delivered by this compound.
Pharmaceutical engineers point out the compound’s role as a precursor for active molecules that shape new therapies. Dye developers latch onto its influence over color quality, stretch resistance, and compatibility with complex polymer systems. With conversations about automation and machine learning creeping into every field, the demand for consistency will only rise. Standardized reagents support data-driven optimization, which means the science can move further, faster.
Every compound, no matter how tried-and-true, runs into limits. For 2-Amino-5-nitropyridine, opinions differ about solubility in specific media, especially as green solvents gain popularity. Blending with modern, bio-based solvent systems sometimes takes longer or gives less pronounced yields. As regulatory agencies rethink exposure limits for nitroaromatics, manufacturers face real work updating their protocols and monitoring systems.
Improvement isn’t just about tinkering in labs. It demands dialogue across research, manufacturing, and environmental admins. The push toward higher purity, better yield, and safer handling spurs partnerships with instrument makers, process chemists, and sustainability teams. Lab managers constantly check for new supply options, greener reaction routes, and waste-reduction strategies. Open communication with regulatory bodies lights the path toward updated best practices—and delivers future-ready chemical products.
My own perspective reflects countless conversations around lab benches, conference tables, and late-night group chats. Learning how 2-Amino-5-nitropyridine adapts across fields makes it clear: no chemical exists in a vacuum. From educators introducing students to the basics of functional group chemistry to scientists pushing the boundaries in drug discovery, the compound delivers lessons in adaptability and resourcefulness.
With new research emerging on functionalized heterocycles, innovation draws on the old standbys like 2-Amino-5-nitropyridine for custom synthesis, bioactive exploration, and material breakthroughs. Teams balance price, reliability, and environmental costs, drawing on both published data and hard-won, real-life lab experience. Feedback cycles between users and suppliers reinforce the shared goal of progress with responsibility, aiming for safer, smarter, and cleaner chemistry.
Rising costs, changing regulations, and global supply uncertainty can disrupt even the most stable workflows. The solution often lies in redesigning sourcing strategies, investing in training, and taking feedback from the floor seriously. By fostering partnerships across disciplines—synthetic chemists, analytical specialists, and logistics teams working together—organizations tap deeper wells of experience and insight.
Updating storage facilities, monitoring real-time environmental footprints, and extending process validation all make a difference for users of 2-Amino-5-nitropyridine. Leaning on established best practices prevents costly recalls and environmental penalties. There’s wisdom in documenting each success and setback, sharing methods, and creating practical checklists for new staff. Building up this shared experience encourages new solutions and keeps teams pushing ahead.
In my own work, the lessons drawn from repeated, careful use of 2-Amino-5-nitropyridine shape both teaching and research. Real learning comes through repeated trials, open mistakes, and the patient development of protocols that survive real-world pressure. Innovation in the chemical sector won’t come from shortcuts or quick fixes, but from a culture that values shared success and hard evidence. Compounds like 2-Amino-5-nitropyridine prove that tradition and progress can align, giving next-generation scientists the tools, context, and confidence to make chemistry safer and smarter.
