|
HS Code |
840133 |
| Cas Number | 3938-89-0 |
| Molecular Formula | C6H7N3O |
| Molecular Weight | 137.14 |
| Iupac Name | 2-amino-5-carbamoylpyridine |
| Appearance | Off-white to light yellow solid |
| Melting Point | 185-190°C |
| Solubility In Water | Moderate |
| Smiles | C1=CC(=NC=C1C(=O)N)N |
| Inchi | InChI=1S/C6H7N3O/c7-5-2-1-4(3-9-5)6(8)10/h1-3H,(H3,8,10)(H2,7,9) |
| Pubchem Cid | 179900 |
| Synonyms | 5-Pyridinecarboxamide, 2-amino- |
| Storage Temperature | Store at room temperature |
As an accredited 2-Amino-5-carbamoylpyridine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The 25g of 2-Amino-5-carbamoylpyridine is supplied in a sealed, amber glass bottle with a secure screw cap and detailed labeling. |
| Container Loading (20′ FCL) | 20′ FCL container can load approximately 10-12 metric tons of 2-Amino-5-carbamoylpyridine, securely packed in drums or bags. |
| Shipping | 2-Amino-5-carbamoylpyridine is shipped in a tightly sealed container, clearly labeled with hazard and handling information. It is protected from moisture, heat, and incompatible substances. The package complies with relevant chemical transportation regulations, ensuring safe delivery. Proper documentation and Material Safety Data Sheet (MSDS) accompany the shipment for safe handling upon receipt. |
| Storage | 2-Amino-5-carbamoylpyridine should be stored in a tightly sealed container, away from moisture and incompatible substances. Keep it in a cool, dry, and well-ventilated area, protected from direct sunlight and sources of ignition. Label the storage area properly and ensure access is restricted to trained personnel. Follow local regulations and safety guidelines for chemical storage and handling. |
| Shelf Life | 2-Amino-5-carbamoylpyridine typically has a shelf life of 2-3 years if stored in a cool, dry, and airtight container. |
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Purity 99%: 2-Amino-5-carbamoylpyridine with purity 99% is used in pharmaceutical intermediate synthesis, where it ensures high yield and minimal impurity formation. Melting Point 192°C: 2-Amino-5-carbamoylpyridine with melting point 192°C is used in solid-state drug formulations, where it provides enhanced thermal stability during processing. Molecular Weight 136.14 g/mol: 2-Amino-5-carbamoylpyridine with molecular weight 136.14 g/mol is used in custom chemical synthesis, where it enables precise stoichiometric calculations. Particle Size <50 µm: 2-Amino-5-carbamoylpyridine with particle size less than 50 µm is used in high-surface-area catalyst supports, where it improves reaction efficiency. Water Solubility 12 g/L: 2-Amino-5-carbamoylpyridine with water solubility 12 g/L is used in aqueous formulation development, where it facilitates homogeneous mixing. Stability Temperature up to 120°C: 2-Amino-5-carbamoylpyridine with stability temperature up to 120°C is used in heat-intensive synthesis processes, where it prevents decomposition and ensures product integrity. UV Absorption λmax 275 nm: 2-Amino-5-carbamoylpyridine showing UV absorption at λmax 275 nm is used in analytical reference standards, where it allows accurate spectroscopic quantification. |
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For people who spend time around high-performance materials, advanced pharmaceutical research, or specialty chemistry, new ingredients aren’t just names and numbers on a label. Each one tells a real story about progress. 2-Amino-5-carbamoylpyridine is a prime example—a compound that keeps appearing on the shoulders of bigger discoveries, making a notable difference without grabbing the spotlight. This isn’t the type of chemical that gets headlines in mainstream media, but in quiet labs and technical settings, it’s well known for showing up when precision truly matters.
This compound draws interest because its structure fits right into the sweet spot for researchers seeking versatility. Its molecular formula—C6H7N3O—places a pyridine ring at the core, with both amino and carbamoyl groups adding extra avenues for reaction and application. The pure powder comes off white to light yellow, which usually signals a high level of purity. Experienced researchers spot that color and know they’re dealing with something that’s ready for more than just routine use.
In the lab, it helps to pay attention to more than just a melting point (which usually lands around 270°C for this compound). Solubility tells another part of the story—2-Amino-5-carbamoylpyridine mixes well with water, so it’s easy to incorporate into aqueous systems. When you look for purity, you’ll often see products within 98–99% range, reassuring chemists that variability won’t get in the way of sensitive syntheses. That matters when the stakes climb in pharmaceutical work and complex organic chemistry, where even modest contamination starts a chain reaction of headaches.
The reputation of this compound stretches beyond textbook synthesis. Medicinal chemists lean on 2-Amino-5-carbamoylpyridine when piecing together active pharmaceutical ingredients. Some use it to build antitumor agents or to set structural frameworks for antibiotics. I’ve spoken to a few people in materials science who rely on it to prepare unique ligands for metal complexes. These applications share a thread: each relies on selective reactivity, and the structural features of 2-Amino-5-carbamoylpyridine give scientists more control when they’re working toward specific outcomes.
Stacking 2-Amino-5-carbamoylpyridine next to more basic pyridine derivatives, the real difference lies in the added functional groups—the amino and carbamoyl. They open up a broader palette for forming hydrogen bonds, connecting to other fragments, and flipping between chemical states as reactions unfold. As a result, chemists can guide molecules down different pathways, landing on products that might prove stubborn with a more rigid or less forgiving starting block.
Not long ago, a colleague explained how swapping in 2-Amino-5-carbamoylpyridine transformed a test reaction by bumping up yields and lowering the energy needed during synthesis. Adding the carbamoyl group let his team fine-tune hydrogen bonding and play with reaction rates in a way that would be tough with simpler pyridine options. These seemingly tiny tweaks piled up, letting the end product stand out for its purity and reproducibility. That’s the kind of edge that stays with you the next time you’re mapping out a multi-step synthesis or troubleshooting why an old recipe no longer works as intended.
For anyone considering a purchase, the question isn’t just “does it do the job?” Instead, it’s more about “what can this provide that my old standbys can’t?” Classic pyridine often offers a cheap and reliable backbone, while 2-Amino-5-carbamoylpyridine stands out when project demands stretch toward specialized drug candidates, ligands, or catalysts. The presence of two separate, reactive sites changes the dynamic—not only in upstream synthesis, but also when these intermediates move toward final products with exacting performance standards.
Every researcher knows the trouble a contaminated or off-specification reagent can cause. Missteps here risk sending whole batches of product out of specification. When aiming for regulated pharmaceutical ingredients, the margin for error shrinks to almost nothing. With 2-Amino-5-carbamoylpyridine, vendors who guarantee and clearly report on analytical data prove invaluable. Assays, high-performance liquid chromatography, and spectral analysis must be taken seriously. From an ethical and professional perspective, skipping these checks means gambling with the reliability of downstream results, which nobody in serious research or production wants.
Cost pressures hit every field, leading some buyers to chase the lowest number and ignore the question of where savings come from. In my experience, repeated issues trace back to false economies: plastic containers, questionable storage, poor traceability, and confusing or undescribed impurity profiles. It’s true for 2-Amino-5-carbamoylpyridine as it is for any specialty reagent—sourcing from reputable producers always pays off. The security of buying with full transparency not only supports better outcomes but also builds good habits for students and colleagues, setting a standard across the lab bench.
In medicine, innovation hinges on building blocks that respond well under pressure. 2-Amino-5-carbamoylpyridine serves as a launch point for several drug discovery campaigns, especially when targeting nitrogen-heterocycle scaffolds where functional diversity is crucial. It’s not about solving every problem, but rather about unlocking molecular shapes and interactions that less complex chemicals simply can’t deliver. This flexibility finds value not just with discovery, but also during optimization, scale-up, and compliance checks, making the compound a behind-the-scenes supporter for teams aiming to address real-world health questions.
Materials chemists see unique value in this compound for the way it supports tailored ligand environments in coordination chemistry. Applications might include base layers for catalysts, frameworks for sensors, or even as a handle to tune the response of new materials to outside triggers—heat, light, chemical environment. These aren’t obvious at first glance, but after attending industry conferences and talking with some specialists, I can vouch for the growing interest. Recent research highlights suggest new catalysts and sensors could lean on the dual reactivity and strong coordination properties of this molecule.
Anyone watching the global shift toward green chemistry knows that small steps can add up quickly. 2-Amino-5-carbamoylpyridine lets chemists skip otherwise hazardous steps by offering a pre-built scaffold with ideal functionalization. The more we adopt building blocks that don’t demand harsh reagents or conditions, the more we avoid unnecessary waste and reduce energy draw. This advantage is subtle, but more labs shifting to sustainable practices recognize that taking care with intermediate selection pays off long-term, supporting both scientific and environmental progress in tandem.
Supply chain hiccups, unexpected shortages, or sudden spikes in demand add tension for those relying on specialty chemicals. Nobody likes realizing that a batch is delayed due to customs holdups or global disruptions. Some teams mitigate these risks by partnering closely with established suppliers, keeping safety stock on hand, or training staff to adjust syntheses when substitution becomes necessary. Information sharing—both between labs and from suppliers—goes a long way toward smoothing out these bumps. The pandemic drove home the value of this collective approach, reinforcing the need for planning and resilience in sourcing chemicals like 2-Amino-5-carbamoylpyridine.
Anyone who’s handled specialty reagents will tell you that storage and handling protocols aren’t a formality—they’re vital for product integrity. Exposure to the elements and poor shelf discipline turn even the purest samples into problems later. Standard practice with 2-Amino-5-carbamoylpyridine involves sealed containers, cool and dry conditions, and careful transfer to avoid moisture uptake. My own rookie mistake, leaving a cap loose on a humid day, led to hard lumps that were tough to dissolve and analyze. Small errors here echo through expensive projects, so good habits save money and protect data quality for everyone involved.
Younger researchers often gain experience by weighing, dissolving, and preparing this compound for multi-step syntheses. These hands-on lessons teach more than chemistry—they ground people in foundational lab discipline and introduce the crucial interplay of structure, function, and safety. Teaching assistants and mentors share that introducing a versatile, well-understood reagent like 2-Amino-5-carbamoylpyridine builds lasting confidence for tackling trickier projects down the line. Good records, eye for consistency, and curiosity about why purity matters are all habits that serve teams well no matter the final destination for the research.
Product listings that commit to real-time documentation of lot analysis, third-party verification, and genuinely clear documentation win trust. Which vendor actually shows spectra instead of summarizing with generic platitudes? Real numbers, including batch impurities, shelf-life information, and changes over time, help labs manage risk and compliance. The chemical business can seem opaque to outsiders, but the shops and distributors who show their math and prove their claims—especially with specialty mid-stage reagents—deserve loyal business.
Scientific progress means new applications and methods show up regularly. Patent filings over the last decade illustrate the growing toolkit surrounding 2-Amino-5-carbamoylpyridine, from click chemistry reactions to bioactive compounds that take advantage of its specific substitution pattern. Research publications also suggest a growing adoption in peptide coupling and nucleoside analog synthesis, where unique hydrogen bonding and adaptability shine. Staying on top of these trends means watching the literature closely, as well as learning from conference abstracts and community feedback from peers who report their own wins and setbacks.
Serious labs take safety guidance to heart. For most pyridine derivatives, that means vigilant personal protective equipment, good ventilation, and swift cleanup of any spills. While 2-Amino-5-carbamoylpyridine doesn’t present exotic hazards, it shares the class’s common risks. Training for new students always includes direct conversations on proper weighing, transfer, and waste handling. Sharing almost-missed accidents keeps teams mindful, so nobody underestimates the routine hazards. My own approach, after a scare involving an unexpected skin contact, has become: gloves up, focus on the task, and double-check before signing off a batch.
Pressure to cut costs threatens careful research. Some administrators or purchasing agents, removed from day-to-day work, push for cheaper options. Results don’t always show the damage immediately. It might take three or four months before patterns of low productivity or data inconsistency catch someone’s attention. On reflection, reworking syntheses or running extra tests burns more time and money than the short-sighted cost savings ever saved. Most seasoned chemists can recount a tale of batches ruined or experiments repeated due to a single off-specification lot. Quality reagents, including 2-Amino-5-carbamoylpyridine, deserve upfront respect, not after-the-fact regret.
Regulatory landscapes keep tightening, especially with biologically active intermediates and pharmaceutical precursors. Regulatory reviews scrutinize batch records, traceability, and chain of custody. This reality isn’t just a headache; it underpins the whole structure of public trust and scientific credibility. Companies that document, trace, and verify shipments of compounds like 2-Amino-5-carbamoylpyridine don’t just keep auditors happy—they form the backbone of a culture where mistakes can be caught early and fixed, rather than discovered in the finished product or, worse, after release. Adopting this mentality serves both compliance and the spirit of good stewardship.
Look ahead, and the map of novel applications keeps widening. As synthetic strategies advance, new uses for scaffolded pyridines pop up, drawing on increased customization and functional complexity. Teams in drug discovery tap this flexibility as they build analogs targeting antibiotic resistance, cancer, and rare diseases. On the industrial side, next-generation sensors, catalysts, and advanced coatings bring more demand for refined, precisely modified building blocks. It’s not a sudden revolution, but a steady, incremental progress that transforms the landscape without fanfare.
For anyone considering whether to add 2-Amino-5-carbamoylpyridine to their research or production workflows, the final verdict won’t come from an abstract or a pitch deck. It arrives through real projects, tested again and again under varied conditions. Trust in the process, patience in evaluating data, and relentless attention to detail all play a part. This compound, though niche, rewards such habits by enabling more robust advances and insulating results from surprise setbacks. Every time a protocol lines up with expectations, every time a student nails the synthesis, every time a team scales up from milligrams to kilograms without a hitch, that’s where the value truly emerges—a combination of chemistry’s rigor and the wisdom gained from experience.
Research teams considering new routes and methodologies should weigh a product like 2-Amino-5-carbamoylpyridine not just in isolation, but in conversation with broader project demands. It’s about meeting regulatory requirements, enabling selectivity and efficiency, streamlining process safety, and supporting teams who depend on reliable building blocks. The closer suppliers and users work—auditing data, requesting documentation, and reporting real-world feedback—the stronger the outcomes for every stakeholder. Scientific advancement isn’t just about molecules; it’s about the structures and relationships that help those molecules deliver for the real world.
Most breakthroughs owe at least part of their success to unsung intermediates and carefully chosen starting materials. Every chemist who’s worked late on a stubborn synthesis, every student who’s puzzled over a new mechanism, every engineer who’s traced a bad batch to its source knows this truth. 2-Amino-5-carbamoylpyridine won’t make headlines, but in the daily rhythm of scientific work it plays a reliable, empowering role. Its strength lies in the ways it helps real people—from seasoned veterans to first-year undergrads—move from promising idea to finished product, again and again.
