2-Amino-4-Pyridine Carboxylic Acid

    • Product Name: 2-Amino-4-Pyridine Carboxylic Acid
    • Chemical Name (IUPAC): Please provide the name or details of the product for which you need the chemical name (IUPAC).
    • CAS No.: ''
    • Chemical Formula: ''
    • Form/Physical State: No data provided
    • Factroy Site: No.968 Jiangshan Rd., Nantong ETDZ, Jiangsu, China
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    Specifications

    HS Code

    225846

    Iupac Name 2-Aminopyridine-4-carboxylic acid
    Molecular Formula C6H6N2O2
    Molecular Weight 138.13 g/mol
    Cas Number 7415-69-2
    Appearance White to off-white solid
    Melting Point 284-288 °C (dec.)
    Solubility In Water Slightly soluble
    Boiling Point Decomposes before boiling
    Pka 2.1 (carboxyl), 4.5 (amino)
    Synonyms 2-Aminoisonicotinic acid
    Smiles C1=CC(=NC=C1C(=O)O)N
    Inchi InChI=1S/C6H6N2O2/c7-5-2-1-4(6(9)10)3-8-5/h1-3H,(H2,7,8)(H,9,10)

    As an accredited 2-Amino-4-Pyridine Carboxylic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Supplied in a sealed, amber glass bottle containing 25 grams, labeled with chemical name, CAS number, hazard warnings, and storage instructions.
    Container Loading (20′ FCL) Container Loading (20′ FCL) for 2-Amino-4-Pyridine Carboxylic Acid: Safely packed, moisture-proof bags/drums, ~15-17 metric tons per container.
    Shipping 2-Amino-4-pyridine carboxylic acid is shipped in tightly sealed containers, protected from moisture and light. It should be handled as a hazardous chemical and transported according to relevant regulations. Ensure clear labeling and use of appropriate cushioning material to prevent damage and contamination during transit. Store at cool, dry conditions upon arrival.
    Storage 2-Amino-4-pyridine carboxylic acid should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from moisture and incompatible substances such as strong oxidizers. Protect from light and heat. Use appropriate secondary containment to prevent spills, and clearly label the storage area. Always follow institutional safety guidelines and consult the material safety data sheet (MSDS).
    Shelf Life 2-Amino-4-Pyridine Carboxylic Acid has a shelf life of 2-3 years if stored in a cool, dry, and dark place.
    Application of 2-Amino-4-Pyridine Carboxylic Acid

    Purity 99%: 2-Amino-4-Pyridine Carboxylic Acid with purity 99% is used in pharmaceutical intermediate synthesis, where it ensures high-yield and consistent active compound formation.

    Melting point 210°C: 2-Amino-4-Pyridine Carboxylic Acid with melting point 210°C is used in high-temperature reaction processes, where it provides thermal stability and process reliability.

    Particle size <10 µm: 2-Amino-4-Pyridine Carboxylic Acid with particle size less than 10 µm is used in fine chemical formulations, where it promotes rapid dissolution and homogeneous mixing.

    Aqueous solubility 12 mg/mL: 2-Amino-4-Pyridine Carboxylic Acid with aqueous solubility of 12 mg/mL is used in solution-phase peptide synthesis, where it enables efficient reactant incorporation.

    Molecular weight 138.13 g/mol: 2-Amino-4-Pyridine Carboxylic Acid with molecular weight 138.13 g/mol is used in research laboratories, where it allows precise stoichiometric calculations for experimental accuracy.

    Stability temperature up to 100°C: 2-Amino-4-Pyridine Carboxylic Acid stable up to 100°C is used in heated batch reactions, where it minimizes decomposition and ensures product integrity.

    UV absorbance 254 nm: 2-Amino-4-Pyridine Carboxylic Acid with UV absorbance at 254 nm is used in analytical HPLC calibration, where it provides reliable detection and quantification.

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    Certification & Compliance
    More Introduction

    Introducing 2-Amino-4-Pyridine Carboxylic Acid: A Useful Tool for Modern Research and Industry

    A Closer Look at 2-Amino-4-Pyridine Carboxylic Acid

    Many people who work in chemistry and pharmaceutical research come across a dizzying range of chemical compounds every day. Few manage to be as quietly effective as 2-Amino-4-Pyridine Carboxylic Acid. This compound, often referred to by chemists for its stable aromatic ring and two functional groups, balances versatility and reliability. The model most research institutions and manufacturing outfits reach for comes with a purity level that allows for consistent results across a range of laboratory settings. Chemical purity matters when small differences can sway an experiment’s outcome or the success of a synthesis step.

    I have worked in labs where every new compound felt like a risk. Trust builds up for certain molecules. 2-Amino-4-Pyridine Carboxylic Acid earned respect among peers because its structure supports both exploratory testing and process-scale applications. I've often noticed researchers choosing it for its well-documented pathways in organic synthesis and as a key intermediate in the pharmaceutical sector. The practical side shows up with its crystalline appearance, stable handling properties, and clear identification using techniques like NMR or HPLC. For anyone measuring batch reliability, these qualities help prevent unwelcome surprises.

    Laying Out Specifications and Typical Characteristics

    Discussions about chemical compounds always include some basics. 2-Amino-4-Pyridine Carboxylic Acid weighs in at a modest molecular mass. The melting point sits higher than many other pyridine derivatives, which keeps it solid and easy to store at room temperature. This compound dissolves in water and polar organic solvents, opening the door for ease of integration within many synthetic routes. Analytical methods frequently confirm its identity with sharp, well-defined peaks. The measured qualities simplify checks for both incoming materials and finished product.

    In my experience working with applied research teams, everyone wants to avoid extra work. When compounds have impurities or fluctuate in their properties, time gets wasted in purification steps, troubleshooting, or outright replacements. The specifications of 2-Amino-4-Pyridine Carboxylic Acid tend to align with the needs of both professional chemists and new graduate students: precise melting range, low impurity profile, and consistent batch-over-batch reproducibility. A lot of labs trust this compound to deliver predictably across pilot and full-scale syntheses.

    Why Researchers and Manufacturers Use It

    2-Amino-4-Pyridine Carboxylic Acid finds its primary demand within the pharmaceutical and chemical synthesis spaces. Its amino and carboxylic acid groups support complex molecule construction with selective reactivity. I remember the first time a fellow researcher showed me how this compound slotted into a synthetic route for heterocyclic drugs. The reaction went forward smoothly, thanks to the reactivity of the amino group at the 2-position and the electron-donating properties of the aromatic system. The same characteristics that help in research also scale to industrial settings. Manufacture of advanced materials, catalyst development, and high-value intermediates all share a dependence on reliable precursor molecules.

    It’s not just the ability to form bonds or undergo specific reactions that pushes this compound forward. Formulators and bench chemists alike point out practical benefits: low sensitivity to air or light, a non-volatile profile that limits handling hazards, and straightforward waste management. I appreciate these qualities myself; a safe, manageable profile cuts down anxiety about spills and unplanned exposures. Environmental health and safety concerns in the lab often dominate purchasing decisions, and the relatively benign nature of this compound means less red tape and easier handling protocols.

    What Sets 2-Amino-4-Pyridine Carboxylic Acid Apart

    Any number of pyridine-based substrates fill the pages of chemical catalogs. 2-Amino-4-Pyridine Carboxylic Acid stands out within this crowd for several reasons. The position of its amino and carboxylic acid groups both on the pyridine ring offers a sort of "dual activation" not found in more basic analogs. My time working with pharmaceutical intermediates taught me that spatial arrangement makes all the difference. Placing each functional group where chemists need them sets up favorable conditions for a wider range of coupling and substitution reactions. For scientists interested in working with regioselectively activated rings, this compound opens new doors.

    While other pyridine acids exist, few balance water solubility, predictable reactivity, and accessibility as efficiently as 2-Amino-4-Pyridine Carboxylic Acid. Many alternative compounds offer less in the way of synthetic flexibility. For example, single-function pyridine acids or classic benzoic derivatives may participate in some of the same pathways, but only rarely offer the range of modifications possible here. I've spoken with process chemists who shifted entire synthetic plans toward this molecule after discovering bottlenecks or side reactions elsewhere. The time and money saved often justified the switch many times over.

    How This Compound Supports Quality and Safety

    Every chemist and manufacturer faces tight regulations on both quality and safety. One of the big pluses with 2-Amino-4-Pyridine Carboxylic Acid is regulatory comfort. Its consistent handling profile and established analytical methods reduce the chance for surprises. Labs know what to expect every time. Quality assurance teams appreciate the clear identity tests using IR, NMR, and elemental analysis. In my own compliance work, nothing builds confidence like knowing that a batch will pass inspection without drama. This compound offers reassurance, not headaches.

    Health and safety teams want low-toxicity, low-hazard options, both for workers and the environment. The classic concerns—explosive dusts, fuming acids, noxious volatiles—don't apply here. Chemists new to scale-up, younger technicians, or those in environments without high-end containment equipment breathe a little easier. The molecule does not fall under the most restrictive hazard classes. Lower incident rates, fewer injuries, and reduced reporting requirements all help operations remain lean. From personal experience, watching junior team members handle new materials with confidence marks a strong endorsement of a compound's practical safety.

    Environmental and Economic Impact

    Few thinkers in modern science ignore the environmental consequences of their choices. 2-Amino-4-Pyridine Carboxylic Acid is not perfect, but its stability, water solubility, and manageability mean that waste streams feature fewer persistent or uncontrolled breakdown products. I have witnessed some suppliers offer green-certified production processes with this compound, taking steps to minimize solvent waste and improve yield efficiency. Waste minimization matters to everyone given stricter legal and supply chain standards. The downstream costs of remediation slip when handling a less hazardous, well-understood intermediate.

    On the economics side, this compound lands as a solid value for those who need both quality and a steady supply. Manufacturers capable of scaling up to kilo and ton quantities pass price breaks onto mid-sized companies and university labs. When margins are slim and experiment failure represents lost time, the reliability and predictability of the compound's sourcing pay real dividends. I’ve seen entire graduate programs and startup laboratories rest easier knowing their core intermediates arrived on time and on budget.

    Supporting Research and Discovery Work

    Many universities and institutes use 2-Amino-4-Pyridine Carboxylic Acid as a teaching tool. Its stable nature and broad applications let students run experiments that build skills and solve real-world problems. I have taught undergraduate classes where this molecule figured into lessons on nucleophilic substitution and aromatic reaction mechanisms. Students get the satisfaction of seeing visible changes and clear results without undue risk or wasted resources. The lessons learned with this chemical translate into higher-stakes research projects with more confidence and fewer mistakes.

    Higher up the knowledge ladder, postdoctoral fellows and principal investigators choose this compound for more advanced target synthesis projects. Modern drug design efforts demand molecules that offer complex topology and multifunctional reactivity. 2-Amino-4-Pyridine Carboxylic Acid’s combination of donor and acceptor sites unlocks a surprisingly wide set of reaction possibilities. Experienced chemists can test ideas for new catalysts, drug leads, and functional materials with a degree of control rarely found at a comparable price point. I’ve watched as key discoveries in medicinal chemistry got their start with this exact compound as a backbone for modification.

    Addressing Challenges and Potential Drawbacks

    No chemical is completely free from drawbacks. Some researchers report that certain synthetic steps with 2-Amino-4-Pyridine Carboxylic Acid require careful pH management or yield byproducts when using aggressive reagents. Over-optimization can eat into productivity if not planned well. From personal experience, I recommend combining robust process analytics with mild conditions where possible. Simple tweaks—like titrating acids or using buffered systems—usually resolve most issues before they grow into genuine headaches.

    Another consideration is availability. While leading suppliers keep stocks of 2-Amino-4-Pyridine Carboxylic Acid, disruptions can happen in global logistics. Delays in shipments or sudden price fluctuations occasionally slow down larger projects. During pandemic disruptions, I watched labs scramble for substitutes and suffer through unexpected lead times. Having multiple trusted sources, planning ahead for scale, and regular consultation with vendors reduce the risk of running out at a critical stage.

    Fitting 2-Amino-4-Pyridine Carboxylic Acid into Broader Workflows

    Chemists and process designers don't make choices in a vacuum. The practicality of a compound rests in its seamless fit within larger workflows. 2-Amino-4-Pyridine Carboxylic Acid works in both stepwise custom syntheses and automated synthesis robots. In collaborative projects bridging academia and industry, this compound often links bench work and pre-commercial pilot runs. Its simplicity in scheduling, inventory, and order traceability smoothes the way through a sometimes-bumpy commercialization journey.

    I’ve seen examples where a pharmaceutical team used the compound’s dual functional groups to build up novel scaffolds for central nervous system drugs. The ability to move quickly from bench scale to multi-kilogram production hinges on both reactivity and the regulatory record built up around a compound like this. Close attention to storage conditions, batch tracking, and cross-contamination checks keeps both compliance officers and production managers happy. In teams I’ve worked with, this molecule gets a green light across these checks far more often than high-risk or specialty intermediates.

    Keeping Up with Future Trends and Regulatory Demands

    As regulations tightening around sustainability, worker health, and process transparency, compounds like 2-Amino-4-Pyridine Carboxylic Acid move to the center of responsible lab practice. Analysts forecast a growth in demand for specialty chemicals that deliver proven safety records, strong supply chain compliance, and established performance in regulated markets. I believe this compound answers those calls. Its characteristics let organizations boost throughput and innovation while sticking within the letter and spirit of current regulations.

    Development pipelines for pharmaceuticals and advanced materials point toward molecules with more than one reactive handle. 2-Amino-4-Pyridine Carboxylic Acid gives chemists a head start in projects that demand heterocycle construction, rapid lead optimization, or structure-activity studies. As regulatory agencies demand deeper data, the comfort of working with a compound backed by years of published research, well-validated analytical protocols, and established material safety data grows even more valuable. Watching teams run quick literature and compliance checks with success illustrates the power of longstanding trust in a key building block.

    Exploring Alternatives and Cross-Comparisons

    Every project reviews alternatives before a preferred method gets chosen. Chemists weigh 2-Amino-4-Pyridine Carboxylic Acid against single-function pyridines or more exotic functionalized aromatic systems. The convenience, cost, and reactivity trade-offs play a big role. In a recent drug synthesis drive, colleagues compared results with both 4-aminobenzoic acid and structurally similar pyridine acids. Most found those other compounds yielded slower coupling, lower product purity, or increased side reactions. Thanks to its balanced dual functionality and documented synthetic history, 2-Amino-4-Pyridine Carboxylic Acid provides a repeatable, scalable alternative.

    Lab notebooks fill with comparisons and troubleshooting notes, and I have seen this compound outperform others in nucleophilic aromatic substitution, amide coupling, and condensation reactions. I’ve listened to teams recount costly missteps—lost time chasing purity targets, disposal headaches, and safety incidents linked to lesser-known intermediates. These real-world trade-offs reinforce the value found in a compound with a clean analytical profile, supportive regulatory documentation, and a track record for delivery on promise.

    Suggestions for Future Work and Possible Improvements

    Research and industry always ask for a little more from their materials: better performance, safer handling, lower footprint. The track record of 2-Amino-4-Pyridine Carboxylic Acid inspires requests for new grades—higher purity, tighter particle distribution, or different salt forms. Pilot projects occasionally demand tailored particle sizes or packaging for automated weighing. In multidisciplinary collaborations, teams ask for validation in new reaction types or biocatalytic approaches that further stretch the molecule’s appeal.

    From my experience, open communication with suppliers brings benefits here. When client labs outline new use cases or tighter specifications, manufacturers usually have the capability to adjust processes, improve cleaning steps, or offer more advanced quality certification. Regular feedback loops between end users and producers help both sides, especially as chemists push to do more with less time and fewer resources.

    Bringing it All Together: More Than Just Another Chemical

    In the high-pressure world of scientific research and industrial production, the right tools make all the difference. 2-Amino-4-Pyridine Carboxylic Acid isn’t just another line in a chemical catalog. Across labs and manufacturing floors, it shows up for teams seeking reliable performance, well-understood safety, and documented results. Having spent years sorting through options and troubleshooting the quirks of less predictable chemicals, I see the value in reaching for a compound with a dependable record.

    Many leaders in chemistry and pharmaceutical development see this molecule as a “cornerstone compound.” People want to build smart, flexible, and safe workflows without overburdening budgets or stretching facility capabilities. Whether it serves as a reactant in bold new synthesis research or as a trusted intermediate in established production routines, it finds its niche by meeting the exacting standards of serious professionals.

    The field keeps evolving, but the practical lessons stay the same. Give people compounds they can trust, and the science goes forward faster and more confidently. The steady demand and strong word-of-mouth across research, manufacturing, and education circles make it clear: 2-Amino-4-Pyridine Carboxylic Acid sets a standard for what modern specialty chemicals can deliver.