2,4-Dichloro-5-pyridinecarboxylic acid

    • Product Name: 2,4-Dichloro-5-pyridinecarboxylic acid
    • Chemical Name (IUPAC): 2,4-dichloropyridine-5-carboxylic acid
    • CAS No.: 3938-89-2
    • Chemical Formula: C6H3Cl2NO2
    • Form/Physical State: Solid
    • Factroy Site: No.968 Jiangshan Rd., Nantong ETDZ, Jiangsu, China
    • Price Inquiry: sales7@boxa-chem.com
    • Manufacturer: Nantong Acetic Acid Chemical Co., Ltd.
    • CONTACT NOW
    Specifications

    HS Code

    627870

    Chemical Name 2,4-Dichloro-5-pyridinecarboxylic acid
    Cas Number 4145-08-6
    Molecular Formula C6H3Cl2NO2
    Molecular Weight 192.00 g/mol
    Appearance White to off-white powder
    Melting Point 203-206 °C
    Solubility In Water Slightly soluble
    Boiling Point Decomposes before boiling
    Density 1.65 g/cm³ (estimated)
    Synonyms 2,4-Dichloronicotinic acid
    Pka 2.7 (carboxylic acid group)
    Storage Conditions Store in a cool, dry, well-ventilated place, away from incompatible substances

    As an accredited 2,4-Dichloro-5-pyridinecarboxylic acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White, sealed HDPE bottle containing 500 grams of 2,4-Dichloro-5-pyridinecarboxylic acid, labeled with hazard symbols and product identification.
    Container Loading (20′ FCL) 20′ FCL: 12 MT packed in 480 fiber drums, each 25 kg net, securely palletized, suitable for international chemical shipment.
    Shipping 2,4-Dichloro-5-pyridinecarboxylic acid is shipped in tightly sealed containers to prevent moisture exposure and degradation. It is classified as a hazardous material and must be transported according to local and international regulations, with proper labeling and documentation. Storage during shipping should be in a cool, dry, and well-ventilated area.
    Storage 2,4-Dichloro-5-pyridinecarboxylic acid should be stored in a tightly sealed container, in a cool, dry, well-ventilated area, away from direct sunlight, heat sources, and incompatible materials such as strong oxidizers. Store at room temperature and avoid moisture. Ensure storage area is clearly labeled, and access is limited to trained personnel to prevent accidental exposure or contamination.
    Shelf Life 2,4-Dichloro-5-pyridinecarboxylic acid typically has a shelf life of at least 2 years when stored in a cool, dry place.
    Application of 2,4-Dichloro-5-pyridinecarboxylic acid

    Purity 99%: 2,4-Dichloro-5-pyridinecarboxylic acid with 99% purity is used in agrochemical synthesis, where it ensures high yield and product selectivity.

    Melting point 204°C: 2,4-Dichloro-5-pyridinecarboxylic acid with a melting point of 204°C is used in pharmaceutical intermediate production, where it facilitates stable processing conditions.

    Particle size <50 µm: 2,4-Dichloro-5-pyridinecarboxylic acid with particle size below 50 µm is used in catalyst formulation, where it provides enhanced reactivity and uniform dispersion.

    Moisture content <0.2%: 2,4-Dichloro-5-pyridinecarboxylic acid with moisture content below 0.2% is used in fine chemical manufacturing, where it reduces side reactions and improves product consistency.

    Stability up to 120°C: 2,4-Dichloro-5-pyridinecarboxylic acid with stability up to 120°C is used in high-temperature polymer synthesis, where it maintains structural integrity and reaction reliability.

    Assay ≥98%: 2,4-Dichloro-5-pyridinecarboxylic acid with assay not less than 98% is used in dye intermediate production, where it assures consistent color quality and batch repeatability.

    Free Quote

    Competitive 2,4-Dichloro-5-pyridinecarboxylic acid prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please contact us at +8615371019725 or mail to sales7@boxa-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: sales7@boxa-chem.com

    Get Free Quote of Nantong Acetic Acid Chemical Co., Ltd.

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Introducing 2,4-Dichloro-5-pyridinecarboxylic Acid: Practical Uses, Quality Insights, and Industry Value

    We Know Our Chemistry: Experience from the Factory Floor

    Over decades of batch stirring and column loading, you learn a thing or two about chemical syntheses that seem simple on paper but demand finesse at scale. 2,4-Dichloro-5-pyridinecarboxylic acid gets plenty of attention these days because of its versatile framework. We know every step of its journey—from raw material to the tightly capped drum—because we craft it ourselves, one controlled reaction at a time. We navigate the shifting tides of regulatory expectations, evolving market needs, and the on-the-ground reality of process controls.

    Detailed Understanding Makes All the Difference

    At our site, every batch tells its own story. Purity isn’t just a number for outside certificates—it’s a story told through sharp melting points, consistent particle morphologies, and a lively debate between QC chemists and operators who know the slightest tweak in conditions shifts your spec. We use raw 3,5-dichloropyridine or the appropriate pyridine derivative, loading it with exacting attention to stoichiometry to avoid off-spec side reactions. Residual sodium or potassium, trace chlorides, and even the hue of the filtrate become checkpoints. That obsessive approach shows up most clearly for those working downstream. Our 2,4-Dichloro-5-pyridinecarboxylic acid often ends up in active pharmaceutical ingredients or as a carefully measured input in complex crop protection compounds, not to mention photographic chemicals.

    Real Specifications, Not Just Numbers

    You’ll hear plenty about purity on technical sheets, but tables never captured the full story. Even two batches that both say “minimum 98% GC” might behave differently downstream. We pay close attention to trace impurities—especially halogenated byproducts and residual solvents—because they disrupt formulation both in pilot plants and at production scale. Particle size distribution drives dispersion and dissolution, so our technical team tracks shifts from run to run, adapting filtration or milling as process demands. Usually our product reaches 98-99% purity; in rare cases, we employ extra purification for demanding custom syntheses.

    Applications: From Field to Lab, Why Manufacturers Rely on Our Material

    Some products claim they “support innovation.” Here, we’ve watched it in practice. In crop chemistry, 2,4-Dichloro-5-pyridinecarboxylic acid is a vital intermediate. Some customers convert our product into pyridine-based herbicides that appear in fields worldwide. In pharmaceutical R&D, this chemical provides a scaffold for creating novel heterocyclic active ingredients, especially those demanding two chlorine substituents judiciously positioned for further elaboration. Photo industry teams, though smaller now than in decades past, still track down our material for special imaging compounds. There’s also a role in custom chemical research, where the pyridine ring serves as a reliable backbone for more ambitious syntheses. We’ve seen demand spike from specialty pigment makers, who need fine-tuned chlorinated pyridines for their proprietary colors.

    What Sets Us Apart from Commodity Supply Chains

    Anyone can repeat what a catalog says. Commodity intermediates move through layers of brokers and traders, and somewhere along that path small losses in quality pile up. By manufacturing ourselves, we get visibility across each step. We’ve invested in containment and powder handling systems; we work with reactors suited to vigorous halogenation, and we routinely inspect crystal habit to minimize clumping. Reproducibility—down to small details—saves headaches. We avoid “exotic” solvents or unfiltered agro feedstocks, which can introduce unexpected contamination. Flexible scheduling lets us shift between kilogram and multi-tonne requirements, whether the end user is a specialty pharma lab or a contract agrichemical formulator.

    Understanding Our Industry's Challenges

    Real production isn’t all blue skies and perfect yields. Chlorinated pyridines generate persistent effluent; safe handling and responsible waste treatment call for investment in both hardware and training. Our dedicated waste neutralization unit keeps us on the right side of environmental compliance, and we close-reactor systems limit operator exposure. That means safer working conditions and consistent supply, even in the face of shifting regulations. Our team keeps certifications up-to-date—and more importantly, we put time into operator education. When chemists and technicians understand both the “what” and “why,” mistakes don’t slip through.

    Some Subtle Differences: 2,4-Dichloro-5-pyridinecarboxylic Acid vs. Other Pyridine Derivatives

    You’ll find many halogenated pyridines available, but not all deliver the same blend of reactivity and stability. Compared to 2,6- or 3,5-derivatives, our acid at the 2,4-positions offers more precise downstream functionalization. It’s not only about the positions of chlorine atoms, but also how carboxylic moiety at the 5-position sets up subsequent coupling or amide formation. Clients working on cross-coupling chemistry point out that different substitution patterns change catalyst requirements and reaction rates. For synthesis of herbicidal or pharmaceutical intermediates, those details dictate which pathway is most efficient, and which byproducts need costly separation. Our product, made consistently from a single source, means fewer surprises in kilo-lab or production plant.

    Troubleshooting and Adaptation: Listening to What Customers Face

    We spend a surprising amount of time talking with customers, far beyond just price and paperwork. Suppose a batch dissolves just a bit slower, or carries a hint of extra color. Our technical support team brings real-world manufacturing experience to track root causes, whether that’s from upstream process changes, ambient humidity, or incoming raw material shifts. We’ve altered crystallization conditions and refined drying temperature ramps to solve caking or sticking. Unusual requests—like extremely fine material for microfluidic devices or low-water content for anhydrous synthesis—go into real production trials. Sometimes a customer needs to scale from 500 grams to several tonnes in weeks. Our internal scheduling flexibility and night-shift operations made those deliveries happen, not some distant intermediary.

    Adaptation to Regulatory Tides

    Compliance doesn’t mean box-ticking. As registration demands tighten, especially in European and North American markets, we devote resources to dossier preparation and impurity profiling. Our product aligns with major global guidances and we keep regular dialogue with authorities. In agriculture, residue limits grow stricter every year. Our operations respond by tracking impurity carryover and adapting both upstream and downstream steps. That also makes a difference for pharmaceutical users, whose regulatory submissions must address traceability down to impurity percentages in decimals. Our plant enables backtracking through logs to confirm consistency for even the most stringent API requirements.

    Process Safety and Reliability: Earning Trust by Doing Things Right

    Manufacturing halogenated pyridines involves risk. We invest in modern engineering controls—local exhaust ventilation, jacketed reactors with precise temperature controls, in-line leak detection—because nothing delays shipments like a near-miss or unplanned shutdown. Operators train on those systems with dedicated job shadowing. Equipment undergoes rigorous inspection cycles. We avoid chasing yield at the cost of operator safety. High-quality products are important, but safe and steady supply carries just as much value for everyone in the chain.

    Supply Chain Realities: Living with Raw Material and Logistics Volatility

    Recent years forced every manufacturer to rethink sourcing and stock management. Our location grants us access to regionally available precursors, but we also keep safety stock for volatile inputs. Crude material deliveries sometimes show seasonal swings, so we’ve built out real-time monitoring of key input parameters—water, halide sources, temperature profiles—to ensure output doesn’t jump in quality. Working closely with logistics partners helps us minimize port delays. We package for durability in transit, thinking about end-user handling as much as trailer transport, reducing risk of spillage or contamination for downstream users. Repeat buyers notice when materials arrive clean, sealed, and labeled for immediate input to their process.

    Environmental Considerations: Striving for Clean, Accountable Manufacturing

    Chemical makers like us work in an era where environmental scrutiny grows every year. Our on-site wastewater treatment removes chlorinated organics before discharge. Waste gas scrubbers and containment cut atmospheric emissions. We’re not perfect—no chemical facility is—but we keep moving in the right direction out of both responsibility and self-interest. Clean operations mean fewer production stops, easier compliance inspections, and more predictable costs for the business. Downstream users in regulated markets benefit when each step in the chain keeps paperwork transparent and effluent minimized.

    Team Expertise and Training

    Expertise accumulates on real shop floors. New chemists rotate through each section, from frontend weighing and mixing all the way to back-end dry room packaging. We keep logs for reaction deviations, yield fluctuations, and filtration bottlenecks, cross-linking each to maintenance notes and shift reports. Instead of rotating workers endlessly, we encourage operators to learn the “why” behind standard procedures. Customers get the benefit of that expertise when small tweaks make the difference between a good batch and a rejected lot.

    Upgrading for Future Needs

    Markets don’t stand still. R&D requests for new derivatives or more tightly defined impurity profiles keep us investing in process modification. We collaborate with formulators to optimize for their downstream requirements—sometimes narrower melting point cutoffs, sometimes added QA documentation for multicountry submission. Equipment upgrades like in-line particle sizing and improved filter caking detection reduce both processing time and off-spec risks. Some customers want pre-packed sub-kilo bottles topped with nitrogen, others need full-scale sacks for drum-scale reactors. Adaptability on the production floor lets us meet those diverse needs.

    Transparency and Traceability

    Trust grows from transparency. Every sale includes batch-specific test sheets and sample retentions. We keep logs on raw material origin, all major process steps, and analytical QC results. Customers facing a finished product deviation can trace all the way back to primary inputs and process conditions. That builds confidence in long-term supply partnerships and avoids the disruption of “mystery” off-spec lots common with poorly sourced intermediates.

    Working Directly Means Less Guesswork and Better Results

    We listen to the labs and plants using our material in real time, not through second-hand reports. Real stories from users shape both troubleshooting and continuous improvement. Direct feedback on pourability, odor, or even batch hue have led us to tweak processes over time. Our product isn’t one-size-fits-all. Instead, it grows with the necessary constraints and creative opportunities of our partners in pharma, agro, research, and specialty chemistry.

    Supporting Creative Synthesis and Sustainable Growth

    Manufacturers need flexibility to keep ahead, and we practice that every day. Our team spends just as much effort on regulatory updates and safety as on maximizing output. 2,4-Dichloro-5-pyridinecarboxylic acid isn’t just another line item—it’s an example of how deliberate, informed process management builds value for everyone down the line. We stand behind our product with facts, years of learning, and open channels to end users that drive continuous improvement—not just for us, but for the future of chemical manufacturing that values both precision and accountability.