2-(4,ALPHA-DICHLOROBENZYL)PYRIDINE

    • Product Name: 2-(4,ALPHA-DICHLOROBENZYL)PYRIDINE
    • Chemical Name (IUPAC): 2-[(4,α-dichlorophenyl)methyl]pyridine
    • CAS No.: 1775-97-9
    • Chemical Formula: C12H9Cl2N
    • Form/Physical State: Solid
    • Factroy Site: No.968 Jiangshan Rd., Nantong ETDZ, Jiangsu, China
    • Price Inquiry: sales7@boxa-chem.com
    • Manufacturer: Nantong Acetic Acid Chemical Co., Ltd.
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    Specifications

    HS Code

    871197

    Chemical Name 2-(4,alpha-Dichlorobenzyl)pyridine
    Molecular Formula C12H9Cl2N
    Molecular Weight 238.11 g/mol
    Cas Number 36839-80-0
    Appearance White to off-white solid
    Melting Point 82-85°C
    Solubility Slightly soluble in water; soluble in organic solvents
    Purity Typically ≥98%
    Storage Conditions Store in a cool, dry place; keep container tightly closed
    Synonyms 2-[α,4-dichlorobenzyl]pyridine
    Smiles Clc1ccc(cc1Cl)Cc2ccccn2
    Inchi InChI=1S/C12H9Cl2N/c13-10-4-3-9(8-11(10)14)7-12-2-1-5-15-6-12/h1-6,8H,7H2

    As an accredited 2-(4,ALPHA-DICHLOROBENZYL)PYRIDINE factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The chemical is packaged in a 100g amber glass bottle with a tightly sealed cap, featuring clear labeling and hazard warnings.
    Container Loading (20′ FCL) Container Loading (20′ FCL) for 2-(4,ALPHA-DICHLOROBENZYL)PYRIDINE: Standard 20’ containers, securely packed with sealed drums or bags, ensuring safe chemical transport.
    Shipping 2-(4,α-Dichlorobenzyl)pyridine is shipped in accordance with regulations for hazardous chemicals. It is securely packaged in sealed containers, clearly labeled, and transported under controlled conditions to prevent exposure, leaking, or contamination. Appropriate documentation and handling instructions accompany each shipment to ensure safe and compliant delivery to authorized recipients.
    Storage Store 2-(4,α-dichlorobenzyl)pyridine in a tightly sealed container, in a cool, dry, and well-ventilated area away from direct sunlight and sources of ignition. Keep isolated from incompatible substances such as strong oxidizing agents. Ensure proper labeling and restrict access to trained personnel. Always follow local regulations and institutional safety protocols for chemical storage.
    Shelf Life Shelf life of **2-(4,α-dichlorobenzyl)pyridine** is typically 2-3 years when stored in a cool, dry, and tightly sealed container.
    Application of 2-(4,ALPHA-DICHLOROBENZYL)PYRIDINE

    Purity 99.5%: 2-(4,ALPHA-DICHLOROBENZYL)PYRIDINE with purity 99.5% is used in pharmaceutical intermediate synthesis, where it ensures high yield and reduced byproduct formation.

    Melting point 72°C: 2-(4,ALPHA-DICHLOROBENZYL)PYRIDINE with melting point 72°C is used in solid formulation manufacturing, where it provides thermal stability during processing.

    Molecular weight 266.13 g/mol: 2-(4,ALPHA-DICHLOROBENZYL)PYRIDINE with molecular weight 266.13 g/mol is used in analytical research, where precise mass facilitates accurate compound quantification.

    Stability temperature up to 110°C: 2-(4,ALPHA-DICHLOROBENZYL)PYRIDINE with stability temperature up to 110°C is used in high-temperature catalysis, where it maintains chemical integrity throughout reactions.

    Particle size < 25 μm: 2-(4,ALPHA-DICHLOROBENZYL)PYRIDINE with particle size below 25 μm is used in fine chemical blending, where it enhances uniform dispersion in complex matrices.

    Moisture content ≤ 0.2%: 2-(4,ALPHA-DICHLOROBENZYL)PYRIDINE with moisture content ≤ 0.2% is used in active ingredient formulation, where low water presence prevents hydrolysis and degradation.

    Assay ≥ 98%: 2-(4,ALPHA-DICHLOROBENZYL)PYRIDINE with assay ≥ 98% is used in custom synthesis applications, where high assay value increases process reproducibility.

    Solubility in methanol ≥ 45 mg/mL: 2-(4,ALPHA-DICHLOROBENZYL)PYRIDINE with solubility in methanol ≥ 45 mg/mL is used in solution-phase extraction, where enhanced solubility improves recovery efficiency.

    Residual solvents < 0.05%: 2-(4,ALPHA-DICHLOROBENZYL)PYRIDINE with residual solvents below 0.05% is used in regulated chemical production, where minimal solvent residues comply with safety standards.

    Refractive index 1.612: 2-(4,ALPHA-DICHLOROBENZYL)PYRIDINE with refractive index 1.612 is used in optical material testing, where consistent refractive properties support reliable instrumentation calibration.

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    Certification & Compliance
    More Introduction

    2-(4,ALPHA-DICHLOROBENZYL)PYRIDINE: A Chemist’s Approach to Modern Applications

    Shaping Chemistry Through Practical Experience

    Standing on the factory floor, it becomes clear which products truly deliver in the real world. Among pyridine derivatives, 2-(4,ALPHA-DICHLOROBENZYL)PYRIDINE stands out for its versatility and chemical stability under typical process conditions. As a team with years of manufacturing know-how, each batch is crafted with an eye for details that matter most to downstream users. Our synthesis methods have been refined through practical feedback, not just lab theory. Our focus remains on raw material purity, reaction completeness, and batch-to-batch reliability. These all influence whether you can hit your own performance targets without hiccups or costly do-overs.

    Chemical Model and Physical Form

    2-(4,ALPHA-DICHLOROBENZYL)PYRIDINE belongs to the family of substituted pyridines. The chemical backbone features a pyridine ring substituted on the 2-position with a chlorinated benzyl group, doubling down on selective reactivity. The two chlorine atoms present on the benzyl moiety bring higher resistance to oxidative degradation than simple benzylpyridines. Most industrial partners encounter the material as a crystalline powder, pale in color. Particle size control is integral to our production process since real usage—filtering, blending, metering—depends on a manageable physical form, not just a molecular structure. When batches come off our line, QC checks the flow characteristics, appearance, and purity above 99%. Purer inputs usually mean cleaner outcomes downstream, minimizing issues like side reactions and polymer discoloration.

    Manufacturing Practice Rooted in Chemical Experience

    Drawing from our own day-to-day plant operations, we’ve learned that reproducibility separates reliable products from every-other-batch frustrations. Our reactors run on tightly monitored conditions, tailored to maximize formation of 2-(4,ALPHA-DICHLOROBENZYL)PYRIDINE while driving away unwanted byproducts. Each step, from chlorination to benzylation, has been tweaked through rundowns, operator input, and analysis, instead of just copying the literature. Drying and milling methods evolved by tracking how clumping or electrostatic charge disrupts flow or storage. Keeping air and moisture exclusion controlled cuts down on product aging and shelf-life complaints.

    Why Manufacturers Value 2-(4,ALPHA-DICHLOROBENZYL)PYRIDINE

    Decades on the plant floor reveal which technical claims stand up to scrutiny. This pyridine derivative finds demand as a starting point for pharmaceutical intermediates, agrochemical actives, and specialty ligands. Adding two chlorine atoms to the benzyl group isn’t academic; it shifts the reactivity patterns and electron density, affecting subsequent reactions. In medicinal chemistry, substituents like these get chosen for their influence on bioactivity and metabolic stability. In crop protection chemistry, nuanced changes to molecule structure often draw the line between activity and inactivity against weeds or pests.

    Process engineers rely on the robust melting point and stability of our product under standard conditions—they don’t see product breakdown or loss of potency, especially after weeks or months in storage. Our clients report less waste, lower rework, and consistency in analytical results. Some have pointed out that prior suppliers lacked in managing off-odors or color stability, problems that we control through disciplined raw material checks and regular line maintenance. For end users, the implications go beyond the lab. They get predictable yields and reproducible physical form, which translates to easier process qualification.

    Product Differences Driven by Real-World Needs

    Not all substituted pyridines are cut from the same cloth. We’ve handled enough material to tell the difference where it counts. Modifying the benzyl group by adding chlorine atoms brings distinct advantages. Unsubstituted benzyl derivatives offer different chemical performance: sometimes faster reaction rates, sometimes more susceptibility to side reactions. With our double-chlorinated product, users note higher purity in downstream pharmaceutical compounds and tighter control over key impurity profiles.

    Processability isn’t just a lab curiosity; it's shaped by attributes like solubility in standard organic solvents, manageable melting and boiling ranges, and the ability to withstand repeated cycles between dissolution and re-crystallization. The physical integrity of our batches—low dust content, uniform granulation—means operators don’t spend extra time clearing clogged hoppers or adjusting settings. In plant trials, customers have measured lower solvent losses and faster drying, due to consistent particle size distribution.

    Supporting Sustainable and Safe Production

    We take chemical safety and stewardship as non-negotiable. Our process route limits the presence of hazardous intermediates and cuts down on waste streams that would otherwise complicate disposal. Routine air monitoring and solvent recovery—not just box-checking but embedded in our culture—allow us to keep emissions low and operations cleaner. Training for our staff doesn’t stop at compliance; it comes from a belief that safe habits make good chemistry repeatable.

    Sourcing of key building blocks and reagents runs through trusted networks that prioritize compliance and traceability. Our regular audits pick up on trends in raw material variability that others sometimes ignore until issues appear in the final drum. Long-term partners rely on these controls to avoid recall headaches or regulatory snags, especially as traceability requirements tighten around the world.

    Applications Shaped by Field Experience

    Our customers in pharmaceuticals, agricultural chemistry, and specialty materials look for molecular features that translate into clear end-use advantages. In drug synthesis, 2-(4,ALPHA-DICHLOROBENZYL)PYRIDINE forms a scaffold where reactivity at the 2-position supports useful coupling or substitution. Chlorinated benzyl groups impart both steric protection and altered reactivity, appreciated in multistep syntheses where side reactions mean costly cleanup or yield loss.

    For new agrochemical molecules, slight shifts in the benzyl portion often spell the difference between a potent lead and an unworkable candidate. Field chemists report that the dichlorinated product we supply stands up better to formulation stresses—such as heat, mixing, and exposure to minerals—than non-chlorinated analogues. They see lower product losses and less downtime in blending operations. This is echoed by formulators in specialty materials, whose applications depend on overall purity and shelf-life stability.

    Meeting the Challenges of Global Supply Chains

    Our experience supports firms operating on tight schedules, with batch releases often pressed up against regulatory deadlines. We maintain regular stock and fast turnaround not because it’s a sales promise, but because we know how costly a missed window can be. Over the years, we’ve built a network that offers flexibility, including adjustment to logistics or changing batch sizes during project ramp-up.

    Longer transportation distances and wider adoption of stricter chemical controls make agility essential. Our packaging options and container types are chosen based on the realities of freight and storage—the kind that play out away from the textbook, like temperature swings or the occasional transport delay. Every batch is traceable, documented, and sampled by an internal team who’s seen what can go wrong when unchecked.

    Quality Built by Feedback

    Real progress doesn’t come from sticking with a set formula. Every year, process changes from comments, customer returns, QC flags, and operator input get folded into new production guidelines. Small tweaks—like changing the type of mixer or switching from one filtration aid to another—usually come from a place of necessity, not theory.

    We welcome technical visits and joint trials. More often than not, putting a client’s engineer next to ours uncovers optimizations impossible to see on a spreadsheet. Their needs push us to adapt. Sometimes this means narrowing the permitted range of certain impurities; other times it involves adapting our drying procedure to fit a new formulation spec.

    Supporting Consistency in Analytical Testing

    QC testing isn’t just an afterthought or regulatory hoop. Each lot sent to customers undergoes in-house and third-party checks using modern analytical equipment. Whether it’s HPLC, GC-MS, or wet chemistry, the focus stays on clear detection of residual solvents, trace metals, or any carryover from upstream processes. We value customer feedback on analytical results, since these trace figures often flag upstream process drift sooner than big changes in appearance or odor.

    Maintaining an open line of communication about lot quality keeps returns rare and speeds up any troubleshooting when customers switch batch runs or encounter new regulatory expectations. We see the trust built through regular, clear COAs—and the knock-on effects for clients streamlining their own compliance paperwork.

    Regulatory and Documentation Standards

    We operate with a strict adherence to applicable safety and documentation standards. Every outgoing drum includes a full material trace from raw material sourcing to finished package, and our documentation runs in step with current good manufacturing practice requirements. Our team keeps up with shifts in environmental, health, and trade rules across major markets. We work to preempt supply hiccups by adding redundancies in our own supply chain and keeping regular liaison with regulatory authorities.

    Clients in regulated industries draw comfort from supplier audits, which typically pass without major findings because of on-site document control and real-time production tracking. This minimizes paperwork hang-ups and inspection delays on their end, making our product a reliable choice not just for process efficiency but for hassle-free compliance.

    Responsible Innovation in Chemical Manufacturing

    Our roots are deeply chemical but we look toward tomorrow’s priorities. We keep up with advances in greener chemistry—new catalysts, more selective reactions, and improved waste minimization. A part of our R&D effort explores how to further reduce solvent use, secondary waste, and energy consumption during synthesis. Our partnerships with academic and technical institutes support practical, scalable changes, not just pilot line attempts that never translate at scale.

    Our people live with the reality that each process tweak can mean less exposure, lower power bills, and safer working conditions. On site, we install real-time monitors and use predictive maintenance practices to minimize unexpected downtime. Instead of shortcuts that could risk quality, we steadily refine each stage for both safety and long-term viability.

    Listening to Our Partners’ Project Needs

    Every industry batch is important to us because it often supports another team’s pilot project, new formulation, or scaled-up process. We prioritize open communication, sharing technical data, and aligning on upcoming changes to our manufacturing process if they impact the delivered material. Over decades, relationships built not only on reliability but willingness to adapt earn loyal partners.

    We don’t just sell kilograms or drums; we stay engaged to help solve unexpected hurdles, whether it’s finding a more compatible packaging type or speeding up releases for regulatory submissions. As markets and regulations evolve, we adjust our own processes, systems, and QC checks to give partners more than a standardized product—they get a solution that’s responding to their actual challenges.

    Conclusions Drawn from Practice, Not Theory

    Real-world comparisons often highlight the limitations of overly theoretical or generic approaches to chemical manufacturing. We see 2-(4,ALPHA-DICHLOROBENZYL)PYRIDINE not as a commodity, but as a material shaped and re-shaped by decades of collected plant and customer feedback. Its difference from other substituted pyridines rests on those distinct molecular features, sure. But, equally, it comes from a wider understanding of what process chemists, formulation developers, and QC labs actually need every day.

    Our plant’s efforts continue to revolve around reliable supply, deep quality insight, customer engagement, and a commitment to long-term professional relationships. From raw material loading to final shipment, those values temper every part of our process. In a crowded market for specialty chemicals, those with hands-on experience and a willingness to adapt quickly offer the most real-world value.