2-Nitroiso-1-Naphthol

    • Product Name: 2-Nitroiso-1-Naphthol
    • Chemical Name (IUPAC): 2-nitro-1-hydroxynaphthalene
    • CAS No.: 22301-44-2
    • Chemical Formula: C10H7NO3
    • Form/Physical State: Crystalline Powder
    • Factroy Site: No.968 Jiangshan Rd., Nantong ETDZ, Jiangsu, China
    • Price Inquiry: sales7@boxa-chem.com
    • Manufacturer: Nantong Acetic Acid Chemical Co., Ltd.
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    Specifications

    HS Code

    229805

    Productname 2-Nitroiso-1-Naphthol
    Casnumber 605-52-9
    Molecularformula C10H7NO3
    Molecularweight 189.17 g/mol
    Appearance Yellow solid
    Meltingpoint 135-139°C
    Boilingpoint No data available (decomposes)
    Solubility Slightly soluble in water, soluble in ethanol and organic solvents
    Density 1.45 g/cm³ (approximate)
    Purity Typically ≥98%
    Synonyms 2-Nitro-1-hydroxynaphthalene, 2-Nitro-1-naphthol
    Storageconditions Store in a cool, dry place, protect from light
    Safetyhazards Harmful if swallowed or inhaled, irritant

    As an accredited 2-Nitroiso-1-Naphthol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 100g amber glass bottle sealed with a screw cap, labeled with hazard warnings and product details for 2-Nitroiso-1-Naphthol.
    Container Loading (20′ FCL) Container Loading (20′ FCL): 14 metric tons (MT) of 2-Nitroiso-1-Naphthol, securely packed in 560 fiber drums, each 25 kg.
    Shipping **Shipping Description for 2-Nitroiso-1-Naphthol:** Ship in tightly sealed containers, protected from light, moisture, and incompatible substances. Handle as a hazardous material—use correct hazard labeling. Avoid sources of ignition. Comply with local, national, and international shipping regulations, including UN numbers and safety data requirements. Consult the SDS for additional precautionary measures.
    Storage **Storage of 2-Nitroiso-1-Naphthol:** Store in a cool, dry, and well-ventilated area, away from sources of ignition, heat, and direct sunlight. Keep the container tightly closed and protected from moisture and incompatible materials such as strong oxidizers. Store in an appropriately labeled, corrosion-resistant container, and avoid contact with acids and bases. Follow all relevant safety and local environmental regulations.
    Shelf Life 2-Nitroiso-1-Naphthol typically has a shelf life of 2-5 years when stored in a cool, dry, and tightly sealed container.
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    Certification & Compliance
    More Introduction

    Understanding the Value and Character of 2-Nitroiso-1-Naphthol

    Direct From Our Reactors: A Look Inside Our 2-Nitroiso-1-Naphthol Product

    Working on a chemical plant floor leaves no place for guesswork. Everything from the temperature of the reaction to the color of the finished powder tells a story about how well the batch turned out. Manufacturing 2-Nitroiso-1-Naphthol (CAS Number 607-85-2), often written as 2-nitro-1-naphthol, gives a good example of this hands-on process where both quality and predictable performance matter. For years, our team has honed this synthesis in large glass-lined reactors, watching everything from how quickly the nitro group attaches to the naphthol ring, to the exact shade that emerges during drying.

    The choice to specialize in 2-Nitroiso-1-Naphthol came after experiences with other naphthol derivatives and observing their quirks. This compound, specifically, fills a need that has resisted cheap substitutions or careless shortcuts. End-users from pigment manufacturers to pharmaceutical researchers have repeatedly described the headaches caused by off-spec batches, mystery impurities, or products sourced through convoluted middlemen. Having direct control has been our way of offering something more reliable and straightforward.

    Product Model, Specifications, and Insights from the Plant

    The material comes off our lines as a bright yellow crystalline powder, with a melting range typically in the 182–185°C window. We track particle size distribution actively, since too many fines slow down filtration, while large particles can hint at incomplete reaction or uneven mixing. Each drum is labeled by production lot, and while we archive full lab reports, the users we speak with care much more about how this behaves in practice rather than tidy tables of numbers.

    Most customers care about two technical markers: purity and solubility behavior. We produce material above 98% by HPLC as a rule, worked out by close control of nitration conditions and careful washing with neutral water to remove inorganic salts. A few buyers aim for even higher purity, especially those in the dye intermediate segment, so we offer select lots with purity upwards of 99%. The residual moisture drives complaints much quicker than any other parameter, so every stage up to final packaging uses nitrogen-blanketed dryers. A damp batch attracts clumping and makes it hard to dose accurately.

    Solubility tends to be a dividing line between applications. In most common organic solvents, 2-Nitroiso-1-Naphthol dissolves well enough at room temperature, but not so aggressively that it creates handling risks during weighing or transfer. The compound’s particular solubility characteristics have earned it a favored spot in those seeking to develop azo dyes or metal complex colorants, mainly because it allows a sharp precipitation and clean filtration during synthesis. We’ve had multiple discussions with formulators who value this predictable behavior, especially when scaling up from the lab to the pilot plant phase.

    Field Experience Sets This Naphthol Apart

    Anyone who has run a reaction using lower-grade naphthol derivatives knows the hassle of unexpected side-color, tarry residues, or persistent odors. Our production approach limits secondary reactions, delivering a consistent color and clean profile batch after batch. We keep impurity profiles tight: most other products in the market carry traces of isomers or incomplete nitration byproducts, which later creep into the customer’s own finished work. In house, we run gas chromatography alongside thin-layer chromatography to identify trouble long before final packing.

    Handling stability often gets overlooked. We heard stories from clients who—after buying from import resellers—opened drums to find caked product or a strong acidic odor indicative of runaway hydrolysis. To address that, our process dries material to below 0.3% weight moisture and uses double-sealed, lightproof packaging. Feedback from pigment plants confirmed they were able to store opened drums for weeks without performance losses, which makes inventory management more forgiving.

    Unlike some naphthol intermediates, our 2-Nitroiso-1-Naphthol contains tightly controlled trace metals. Color chemistry is sensitive to even small iron or copper contaminants. Some sector standards tolerate up to 100 ppm, but we’ve pushed our process to keep this well under 10 ppm. In field use, this results in more reliable hues, fewer surprises during shade matching, and a lower need for corrective rework.

    Applications: What We’ve Learned in Real-World Use

    The most frequent application requests revolve around azo pigment synthesis, especially orange and red shades used in plastics or ink formulations. Our partners in the pigment industry use 2-Nitroiso-1-Naphthol to anchor the nitro group’s effect on color vibrancy. Working on joint projects, we’ve measured the difference in light fastness and migration resistance between batches made with well-controlled intermediates and those sourced irregularly. Even slight variations in naphthol purity can mean a full point difference in fade-resistance statistics after accelerated weathering.

    Dye makers value the way this molecule’s solubility and reactivity balance out during coupling. They report sharper cut points and quicker filtration during diazotization. In the few pharmaceutical research projects involving this naphthol, the focus shifts toward avoiding trace byproducts, so we share not just final purity but also side-product fingerprints to help qualify material for projects running under pharma GMP.

    Another steadily growing area turns up in specialized research labs. Our team has seen requests for 2-Nitroiso-1-Naphthol in catalyst studies, photochemical work, and niche organic transistor research. In those environments, the demand is more about reproducibility between lots. We routinely supply small-batch specialty cuts with full analytical disclosure, since even subtle differences in melting point or ash content can derail these experiments. Our ability to match chromatographic profile across yearly campaigns often wins the repeat business.

    Direct communication with end-users has taught us that easy traceability, prompt documentation, and being able to answer detailed questions about plant procedures matter more than any generic web page claim. We offer not just standard SDS and CoA, but written background on how particular lots were processed. This openness meets growing buyer concern around regulatory compliance and supply chain transparency, especially for those aligning new R&D with REACH or US TSCA guidelines.

    Why Not All Competing Products Measure Up

    While some suppliers claim high purity or consistent lots, much of the global supply relies on older plant equipment, batch-to-batch variability, or independent traders mixing materials from different sources. We invested in standardized reactor controls, validated filtration sequences, and trained staff who have run hundreds of campaigns with the same feedstocks and process logic. This tight integration reduces the risk of contamination or mislabeling, an issue industry insiders know too well.

    In a market driven by price and speed, corners sometimes get cut. Broad-purity ranges, barrels relabeled en route, or poor-quality documentation lead to headaches downstream—especially during regulatory inspections or critical project phases. Our experience with root-cause investigations proves that consistent, well-characterized chemical intermediates prevent downtime or scrapped product shipments. One large pigment producer described trimming their finished lot reject rate by 40% after transitioning to direct-purchase from our plant.

    While some products attract attention for their cost-saving, downstream issues often cancel out any notional savings. Blotchy color runs, difficult dissolutions, or reworking filter cakes cost far more in the long run. The time saved by using a consistent product—plus the security of traceable origin—often outweighs a lower unit price. Direct clients, especially those regulated under international chemical safety regimes, told us product recalls due to impurity flags have dropped sharply. Here, verified batch histories and unaltered analytical reports carry significant weight.

    Process Quality and Traceability as the Backbone of Reliability

    Our plant teams learned long ago that controlling temperature and pH at the right points in the synthesis keeps side-products to a minimum. Regular in-process controls—sampling the reaction mass, testing for color strength, following the aroma profile—allow us to predict and steer each batch. We learned that not all analytical labs have experience distinguishing the relevant isomers; by working closely between plant and lab, subtle mistakes get noticed and corrected far earlier.

    The manufacturing know-how accumulated over years—like skillful washing to remove unreacted acids, careful solvent swaps, and controlled drying—translates to a naphthol intermediate that carries fewer surprises. Every time we see a customer return for multiple campaigns, the importance of granular process discipline gets reinforced. Regulatory changes also keep raising the bar, so traceability and full batch logging, right down to which reactors and operators handled a lot, have become nonnegotiable.

    Shipping hazardous intermediates internationally is not just paperwork. Properly stabilizing 2-Nitroiso-1-Naphthol for export—especially under new IMDG and IATA regulations—requires both experience and anticipation. Each batch is logged, with certificates of analysis and supplementary quality packages available on request. Real-world packaging feedback—handling drums in unheated warehouses, customs inspections, and on-site decanting—all feed back into how we label, seal, and reinforce containers.

    Supporting Your Work: Real Answers for Real Processes

    We recognize the practical questions chemists and engineers face every day. Will a new lot dissolve the same way as the last? Does the product flow well through my automated loaders? Has the batch picked up unwanted odorous traces? Can I track it if there is any issue downstream in my process? These are not just checkboxes but daily concerns. Hearing back from users, we adjust our operating procedures to match both market changes and new regulatory expectations.

    Industry experience tells us that sharing not just purity specs, but also detailed impurity catalogs, lot histories, and even full reactor logbooks for audit purposes helps build user confidence. Buyers balancing price, performance, and compliance care more about avoiding surprises than chasing marginal cost savings. In direct conversations, we often walk through both the chemistry and the logistics, helping customers qualify new lots and trouble-shoot unexpected reactivity or shading changes.

    We make a point to avoid claims we cannot trace through our own hands. Every kilo leaving our gate comes with a story—not only of the chemistry behind it, but the people and processes that shaped it. Users who have faced risk from unknown suppliers see the value in being able to call up details about a specific lot years after shipment. Industry shifts toward sustainable sourcing and chemical control make this approach not just attractive, but essential.

    Comparing Against Other Products: Details Matter

    Sourcing 2-Nitroiso-1-Naphthol directly from a manufacturing plant, rather than through intermediaries or re-labelers, offers several real-world advantages. Key among these is confidence that supply isn’t vulnerable to sudden quality drops caused by switching origin. Many customers talk about the frustration of variability when re-sourced goods suddenly show new analytical quirks or diminished performance. For companies aiming for process consistency and regulatory assurance, this direct traceability is non-negotiable.

    Comparing to similar naphthol derivatives, the unique nitro positioning (at the 2-side of the 1-naphthol) changes both reactivity and behavior during downstream synthesis steps. In practical use, this causes differences in coupling speed with diazonium salts, chromatic purity in the resulting pigments, and precipitation properties in water or organic systems. Engineers focused on reducing steps in color filtration or simplifying product workup have commented on the “clean break” and reproducible color hues, even over long production runs.

    While substitutions exist for some applications—say, other nitro-naphthols or different ring-isomer ratios—customers in fields like pigment manufacture or specialty dye research report frequent problems using alternate products. Challenges include unexpected color drifts, lower pigment yield, or slower processing times. Years of supplying to these sectors taught us that shortcuts in intermediate quality create costs elsewhere in the plant—costs often measured in lost batches or line downtime.

    For investigators at the bench, repeatable analytical profiles between lots are essential when comparing new catalyst systems or photochemical reactions. Research groups return to our product not simply for published specification, but because each batch matches the last, letting them troubleshoot using chemical logic rather than wondering if the starting material changed.

    Closing Observations from the Production Line

    The naphthol field rewards those with a long view. Our teams have stood next to reactors through power failures, supply chain gluts, regulatory reviews, and export bottlenecks. What endures through all this is a focus on reproducibility, honesty about process variables, and an open channel to the users committing their own resources downstream.

    Direct production of 2-Nitroiso-1-Naphthol continues to prove that close control, detailed records, and willingness to adjust according to feedback earns more trust than any abstract marketing. Enthusiasm comes more from the quiet satisfaction of hearing that a specific pigment run, a dye development project, or a next-generation research effort succeeded thanks to reliable starting materials. That sense of shared success, measured not in grand gestures but in kept commitments and problem-free campaigns, defines the difference we try to bring to every shipment.