1-(4-Sulfophenyl)-3-Carboxy-5-Pyrazolone

    • Product Name: 1-(4-Sulfophenyl)-3-Carboxy-5-Pyrazolone
    • Chemical Name (IUPAC): 5-oxo-1-(4-sulfophenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid
    • CAS No.: 156628-08-5
    • Chemical Formula: C10H7N2O5S
    • Form/Physical State: Solid
    • Factroy Site: No.968 Jiangshan Rd., Nantong ETDZ, Jiangsu, China
    • Price Inquiry: sales7@boxa-chem.com
    • Manufacturer: Nantong Acetic Acid Chemical Co., Ltd.
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    Specifications

    HS Code

    826829

    Product Name 1-(4-Sulfophenyl)-3-Carboxy-5-Pyrazolone
    Molecular Formula C10H8N2O6S
    Molecular Weight 284.24 g/mol
    Cas Number 138-43-0
    Appearance Yellow to orange powder
    Solubility Soluble in water
    Melting Point 270-274°C (decomposes)
    Purity Typically ≥98% (varies by supplier)
    Ph Of 1 Solution Approx. 3.5-4.5
    Storage Conditions Store at room temperature, protected from light and moisture
    Synonyms Sodium 1-(4-sulfophenyl)-3-carboxy-5-pyrazolone; Carboxy-PTZ
    Stability Stable under recommended storage conditions
    Usage Analytical reagent, especially for spectrophotometric determination of certain metal ions

    As an accredited 1-(4-Sulfophenyl)-3-Carboxy-5-Pyrazolone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 25g quantity of 1-(4-Sulfophenyl)-3-Carboxy-5-Pyrazolone is packaged in a sealed, amber glass bottle with tamper-evident cap.
    Container Loading (20′ FCL) 20′ FCL can load 8.4MT of 1-(4-Sulfophenyl)-3-Carboxy-5-Pyrazolone packed in 25kg bags on pallets, safely shipped.
    Shipping 1-(4-Sulfophenyl)-3-Carboxy-5-Pyrazolone is shipped in secure, airtight containers to prevent moisture absorption and contamination. The packaging complies with chemical safety regulations, ensuring safe transit. Shipping is typically via ground or air freight, with accompanying Material Safety Data Sheets (MSDS) and hazard labeling as required for laboratory chemicals.
    Storage **1-(4-Sulfophenyl)-3-Carboxy-5-Pyrazolone** should be stored in a tightly sealed container, protected from light, moisture, and incompatible substances. Store at room temperature in a well-ventilated, dry area away from strong oxidizing agents. Ensure proper labeling and avoid exposure to heat sources. Follow all relevant safety guidelines and local regulations for chemical storage.
    Shelf Life 1-(4-Sulfophenyl)-3-Carboxy-5-Pyrazolone has a typical shelf life of 2–3 years when stored in a cool, dry place.
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    Certification & Compliance
    More Introduction

    Introducing 1-(4-Sulfophenyl)-3-Carboxy-5-Pyrazolone: Factory Insights from the Manufacturer

    What Makes This Compound Stand Out

    After years spent at the intersection of bench research and scaled production, our team has learned to pay close attention to the real-world properties of specialty intermediates. 1-(4-Sulfophenyl)-3-Carboxy-5-Pyrazolone, also known around the plant as SCP, carries a profile that rewards attention to detail on the shop floor, not just in the lab notebook. Each batch is a direct reflection of the raw materials, reaction controls, and purification steps. Our experience with this molecule puts us in a position to discuss what it does—and what makes it different from similar compounds.

    Material Profile: Beyond the Technical Data

    Consistency matters in large-scale synthesis. Over hundreds of runs, we’ve come to recognize that the most common form of SCP delivered from our reactors is a pale yellow to beige powder. With purity fine-tuned over repeated crystallization and drying processes, losses from basic yield-improving tweaks mean little compared to the reliability our customers come to expect. We usually supply lots above 98% on HPLC, since anything below may introduce too much background noise for sensitive downstream applications. Moisture levels stay tightly controlled—our inspection process picks up even small deviations after vacuum drying, and loose or sticky samples never reach packaging.

    For solubility, technicians in both R&D and QC labs tell us that SCP dissolves readily in deionized water, and shows notable stability in buffered aqueous systems—an advantage during complexation or as a ligand in analytical protocols. We avoid milling to ultrafine particles unless requested, since some clients have explained that excess dust complicates handling or bottling on automated lines. The compound’s pKa and UV absorption profile, with strong chromophores around 355-360 nm, give it a defined niche among chelating agents. We monitor color index during processing as a practical quick-check for purity and to flag runs that need rework.

    Experience in Production: Lessons Learned

    Our process rarely runs on autopilot. Raw material choice, particularly for the phenylsulfonic acid precursor, changes the outcome. Early on, batches using crude or merchant-grade precursors resulted in off-color or non-crystalline SCP—something we traced back to trace organics or varied sulfonation degrees. A clean supply chain for starting materials means fewer production hiccups and minimal filtration difficulties. Our plant operators know that the correct temperature profile during ring closure defines product consistency. Deviations, even a few degrees, show up as loss of product or more colored by-products. Many of our improvements have come at the suggestion of the crew measuring volumes every day, who have learned to spot when a batch is “off” before the analytics confirm it.

    Different drying conditions matter. Extended oven drying, compared to vacuum, leads to subtle changes in appearance and hygroscopicity. Early on, we ran some test lots through each route, and found that vacuum drying consistently resulted in powder that stored better and packed well for shipment. Some customers, especially those reconstituting SCP at high concentrations, gave direct feedback: lots kept under tight humidity control responded far better, with fewer clumps and minimal degradation.

    Applications: Real-World Uses and Client Stories

    Feedback from our customer base covers a surprising gamut of uses. In dye and pigment research, SCP forms a key intermediate for azo dye synthesis—its dual functionality, with both the carboxyl and sulfonic acid groups, allows for diverse couplings. We have seen textile labs favor this molecule for its superior water solubility compared to standard pyrazolone derivatives. These users have noted that SCP offers brighter shades and easier filtration in their process streams, saving both time and resources.

    Laboratory chemical suppliers, many of whom prefer buying from the original manufacturer, have explained that SCP’s structure, especially with its electron-withdrawing sulfonic group, delivers higher selectivity during metal complexation. Those in water treatment chemistry echo similar advantages. Complexes built from SCP frequently outperform simpler ligands when precise detection or scavenging is required. A few industrial metal analysis companies use SCP to chelate a specific set of transition metals, noting that alternatives—such as carboxyphenyl pyrazolones lacking a sulfonic acid—fall short under lower pH or in high-salt matrices.

    Our R&D customers in medical diagnostics have given practical feedback on stability. Unlike less polar analogs, SCP maintains its structure during prolonged storage, even when open vials or in dissolved form. A client once detailed a side-by-side accelerated aging trial, finding that related compounds broke down, while SCP still delivered accurate calibration signals. This kind of feedback tells us the synthetic route, purification, and packaging standards are delivering real benefits, not just theoretical ones.

    What Sets SCP Apart from Similar Pyrazolones

    Chemists familiar with 3-carboxy-5-pyrazolones quickly spot the unique addition of the para-sulfonic acid group. In our own bench trials, we have compared SCP with its unsubstituted and meta-sulfonated cousins. Most notably, we’ve found that the para-sulfonic group shifts both reactivity and handling. It dramatically enhances water solubility at neutral and alkaline pH. Teams working with low ionic strength applications prefer SCP, since it resists precipitation under conditions where other analogs form suspensions or poorly dissolving crystals.

    During our own development phase, we tried replacing SCP with structurally similar compounds. Many of them failed key performance checks. For instance, unsubstituted pyrazolones or those lacking the carboxylic acid show lower metal binding at relevant pH. In dye chemistry, these alternatives produced duller or more unstable coloration. SCP’s unique structure allows for consistent and reproducible results, especially in analytical and coating applications. Colleagues who run instrument calibration for process analyzers say SCP’s spectral fingerprint stands out, giving them confidence in both quantitation and trace detection work.

    Another key difference turns up in environmental handling. After a few accidental spills, our safety and cleanup teams noted that SCP’s water solubility simplifies containment and removal compared to oilier pyrazolones. Because we handle cleanouts ourselves, any reduction in persistent residues translates to both time and cost savings on the plant floor.

    Working with SCP: Direct Experience from the Factory Floor

    Producing 1-(4-Sulfophenyl)-3-Carboxy-5-Pyrazolone isn’t just a matter of setting up a reaction and walking away. Operators at the blending station learned that proper agitation speed ensures a uniform reaction, while over-stirring triggers unnecessary foaming. Early runs that overlooked the significance of pH control faced low yields and difficult filtering. After a few lessons earned the hard way, we built continuous monitoring of both pH and temperature into our standard protocols. Yields improved and batch-to-batch variation dropped sharply.

    Our packaging division sees the final stages. Any exposure to ambient air can introduce clumping, so every container runs through double-sealed lines. On more than one occasion, long-term customers have sent back unused material for quality checks, and in every case, SCP that’s been packed right holds its texture and purity even after lengthy storage.

    Shipping practices changed after a few initial export orders arrived with caked product. We overhauled the inner packing layer and added silica gel packets based on feedback from hot and humid regions. The change reduced post-shipment complaints and, in many cases, brought direct thanks from clients whose workflows depend on predictable reconstitution and dosing.

    How We Handle Quality and Sourcing

    No discussion of SCP would be complete without mentioning the importance of predictable raw material supply. We work directly with our trusted upstream partners, always running incoming analysis that matches the rigor of our own output checks. In one memorable case, new lots of a key starting aldehyde from a less established source passed supplier checks but failed on our internal screening for trace impurities. After isolating the issue—a tertiary organic contaminant—we returned the entire consignment. Since then, we rely only on those suppliers whose analytical results hold up after weeks of high-throughput production.

    We often revisit our process documentation, based on both internal audits and customer outcomes. On a few occasions, input from teams downstream of our operations uncovered subtle but important points; for instance, a recurring minor impurity pattern traced back to a cleaning solvent that left low-level residues. Adjusting the wash protocol eliminated the impurity and, as a result, increased end user confidence.

    Handlers in the warehouse note that storage temperatures matter: SCP shows optimal shelf life at ambient cool and dry conditions. On hot, humid summer days, they monitor storage chambers more closely, and rotate inventory to keep supplies as fresh as possible. Clients large and small have come to value direct shipping from our controlled warehouse facilities rather than third-party logistics operators, as this keeps chain of custody uncomplicated.

    Supporting Real People in Real Operations

    A technician in a spectrophotometry lab once called seeking explanation for a sporadic spectral baseline jump when using unopened bottles. Our technical support manager walked through their entire process, traced the deviation to local water quality issues, and suggested using high-purity pre-mixed buffer kits alongside the SCP. Subsequent runs came out flawless. This level of support can only come from those who understand both the chemistry and the realities of downstream workflow. Over dozens of such interactions each season, we build up not just a service record, but a true knowledge base grounded in day-to-day experience.

    Even in small pilot facilities, users share how tight batch records, full synthesis transparency, and open technical dialogue help avoid missed steps or out-of-spec results. Direct communication between our manufacturing plant and the end users avoids the guesswork that often happens when material passes through several hands before reaching its destination.

    The Value of Working With the Originator

    Original manufacturers don’t just produce and ship: we live the lifecycle of the molecule day in and day out. If an unplanned stoppage comes up—such as supply interruption of a key input—teams meet on the floor to rework schedules and work up alternatives. Onsite know-how ensures contingency batches retain expected purity and performance. One lesson learned: having every instrument and protocol linked to a specific line operator’s experience leads to fewer errors when unexpected process drifts arise.

    Supply chain managers reporting to the plant highlight order-to-shipment lead times, which, while not always the shortest, provide a degree of reliability that batch brokers or resellers rarely match. Customers seeking special packing, mill size, or documentation can touch base directly and receive personalized solutions, not just templated answers.

    Environmental Practices and Practical Outcomes

    Waste management is part of our process from start to finish. All liquids, even rinse water from the finishing room, go to in-house treatment. We target recovery rates for byproducts at over 90% and routinely send effluent for verification at independent labs. Once, after spot-checks indicated a trace spike in sulfonate residues, the team changed up downstream treatment—result: all readings well below allowed endpoints.

    Packaging improvements also came from operator feedback: shifting to recyclable, moisture-sealed containers in all pack sizes led to less breakage, reduced customer waste, and fewer in-process spills on our own lines. We log and trace all outgoing shipments, which helped resolve a case where a client puzzled over minor product loss—the culprit proved to be old-style bottle seals, which we have since replaced.

    Reliable SCP: More Than a Commodity Chemical

    In this business, every kilogram tells part of the story. Customers in industries from analytical kit manufacturing to dye research report direct benefits from quality consistency, rapid technical support, and a supply chain that connects raw materials to end-product with no gaps. 1-(4-Sulfophenyl)-3-Carboxy-5-Pyrazolone sits in a class of its own not simply due to its molecular structure but because of the hands-on commitment of those who make, ship, and stand behind it.

    We see daily proof that real manufacturing experience matters: from the way a technician seals a drum to the speed of answers when a process change needs confirmation. This level of reliability does not spring from generic data sheets, but from ideas and labor turned directly into tangible results. Customers know they can call with a practical question or application oddity and receive advice based in hands-on understanding—something only possible with a manufacturer’s perspective.

    A Collaborative Future

    Our relationship with 1-(4-Sulfophenyl)-3-Carboxy-5-Pyrazolone spans decades, rooted in test runs, improved controls, process tweaks suggested by operators, and direct discussion with end users. Every improvement serves the next batch, and every client story adds another data point that sharpens both our process and the product itself. From robust supply lines to fast, authoritative support, we build not just batches, but a foundation for continued discoveries and applications.

    With specialty intermediates, the full story never fits on a spec sheet. It lives in the shared experience of those who make, refine, and apply the molecule—from the first raw materials arriving in the yard to the finished product reaching laboratories all over the world. Our promise is that each drum, box, and bottle reflects not only chemical purity but also the constant attention and improvement that define real manufacturing.